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Hypotheticals Return - not actual results!   Base Value: $431,205,565 Current Value: $470,569,868 Change: $39,364,303 Performance: 9.12 %

Name: Perceptive Advisors Llc Last Trade: 2010-02-16 Owner Class: Institution Address: 499 Park Avenue, 25th Floor,New York Ny 10022,, Phone: 646-205-5340 Fax: Website:

Stock Trading Hypotheticals

Hypotheticals use the owners holdings and changes reported as a model portfolio combining with stock price changes between the base price date and end price date. All results/returns are hypothetical and are not actual results!

Worst Move:	Lost $-5,333,212 on changes made with Medivation Inc (MDVN) buying shares when price went down.
Best Move:	Made $14,934,759 on changes made with Intermune Inc (ITMN) buying shares when price went up.
Best Save:	Saved $-5,049,000 on changes made with Osi Pharmaceuticals Inc (OSIP) selling shares when price went down.
Missed Move:	Missed $315,000 on changes made with Amag Pharmaceuticals Inc (AMAG) selling shares when price went up.

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Perceptive Advisors Llc Stock Trading

Show ALL transactions instead of just the most recent 10:
Use 'As-Of/On' instead of 'Filed' for dates:		Begin date:		End date:
A begin price of 1900-01-01 will use the date filed for begin price:		Begin Price date:		End Price date:
- report date span limited to 100 days, all dates in format of yyyy-mm-dd, all fields required!

Transactions: Currently showing holdings/transactions Filed between 2009-11-18 and 2010-02-16

Prices: Currenty using base stock prices on Filing Date compared to stock prices on 2010-03-19

Show/Hide Columns Of Stock Trading Details

Filed	As-Of/On	Form	FullName
Symbol	Country	Industry	Shares
Activity	Shares Change	Shares Change Pct.	Hypothetical Old Value
Hypothetical New Value	Hypothetical Value Change	Hypothetical Return	Hypothetical Results
Director	Ten Pct	Other	Officer
Officer Title	History

Stock Trading: Ten Trades Most Recently Reported

Filed	As-Of/On	Form	Fullname	Symbol	Country	Industry	Shares	Activity	Shares Change	Shares Pct. Change	Hypothetical Old Value	Hypothetical New Value	Hypothetical Value Chg.	Hypothetical Return	Hypothetical Results	Director	Other	Ten Pct	Officer	Officer Title	History
2010-02-16	2009-12-31	13F-HR	Penwest Pharmaceuticals Co	PPCO	US	Drug Delivery Systems	6,476,446	Added More	1,850,000	39.98 %	$15,932,057	$22,797,090	$6,865,033	43.08 %	$1,961,000						History of Perceptive Advisors Llc Ownership Of Penwest Pharmaceuticals Co
2010-02-16	2009-12-31	13F-HR	Poniard Pharmaceuticals Inc	PARD	BE	Medical-Drugs	2,050,000	Sold Some	-1,476,300	-41.86 %	$3,300,500	$3,198,000	$-102,500	-3.10 %	$73,815						History of Perceptive Advisors Llc Ownership Of Poniard Pharmaceuticals Inc
2010-02-16	2009-12-31	13F-HR	Amylin Pharmaceuticals Inc	AMLN	US	Therapeutics	1,200,000	Added More	1,000,000	500.00 %	$21,780,000	$26,988,000	$5,208,000	23.91 %	$4,340,000						History of Perceptive Advisors Llc Ownership Of Amylin Pharmaceuticals Inc
2010-02-16	2009-12-31	13F-HR	Genvec Inc	GNVC	US	Medical-Biomedical/Gene	0	Sold All	-950,000	-100 %	-	-	-	17.08 %	$-389,500						History of Perceptive Advisors Llc Ownership Of Genvec Inc
2010-02-16	2009-12-31	13F-HR	Supergen Inc	SUPG	US	Medical-Biomedical/Gene	864,227	New Holding	864,227	100 %	$2,480,331	$2,800,095	$319,764	12.89 %	$319,764						History of Perceptive Advisors Llc Ownership Of Supergen Inc
2010-02-16	2009-12-31	13F-HR	Vivus Inc	VVUS	US	Therapeutics	513,000	Sold Some	-859,000	-62.60 %	$4,447,710	$4,514,400	$66,690	1.49 %	$-111,670						History of Perceptive Advisors Llc Ownership Of Vivus Inc
2010-02-16	2009-12-31	13F-HR	Cell Therapeutics Inc	CTIC	US	Medical-Biomedical/Gene	1,300,000	Added More	850,000	188.88 %	-	-	-	- %							History of Perceptive Advisors Llc Ownership Of Cell Therapeutics Inc
2010-02-16	2009-12-31	13F-HR	Wyeth	WYE	US	Medical-Drugs	0	Sold All	-775,000	-100 %	-	-	-	- %							History of Perceptive Advisors Llc Ownership Of Wyeth
2010-02-16	2009-12-31	13F-HR	Avi Biopharma Inc	AVII	US	Therapeutics	2,841,019	Added More	630,000	28.49 %	$4,147,888	$3,664,915	$-482,973	-11.64 %	$-107,100						History of Perceptive Advisors Llc Ownership Of Avi Biopharma Inc
2010-02-16	2009-12-31	13F-HR	Intermune Inc	ITMN	US	Medical-Biomedical/Gene	956,396	Added More	594,300	164.12 %	$14,967,597	$39,001,829	$24,034,231	160.57 %	$14,934,759						History of Perceptive Advisors Llc Ownership Of Intermune Inc

Returned 10 Records!

Stock Trading Sources
Form Type	Filed	As-Of/On	Sec Filename
13F-HR	2010-02-16	2009-12-31	edgar/data/1224962/0000909012-10-000152.txt

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Note: All amounts are based on price of stock at date reported versus the current price! They do not represent actual profit/loss! There has been no adjustmentsfor splits!

Note: All amounts in USD, converted using Intrabank Exchange Rate on Date Reported/Today

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