Adage capital partners gp llc - see footnote investment history in Cardiome pharma corp

Filed on 2010-04-16 by Adage Capital Partners Gp Llc SEC CIK 1165408 Form 4

Accession 0000902664-10-002425.txt Sec File: edgar/data/1165408/0000902664-10-002425-index.htm

2010-04-14 Adage Capital Partners Gp Llc (CIK 1165408) through See Footnote

Invested in Cardiome Pharma Corp sold 650000 shares at $7.92 remaining shares owned 6700000

Common Shares No Par Value Cardiome Pharma Corp Crme Transaction code: S Open market or private sale of securities

f1 adage capital partners gp, l.l.c., a delaware limited liability company ("acpgp"), serves as the general partner of adagecapital partners, l.p. (the "fund"), and as such has discretion over the portfolio securities beneficially owned by thefund. adage capital advisors, l.l.c., a delaware limited liability company ("aca"), is the managing member of acpgp anddirects acpgp's operations. robert atchinson and phillip gross are the managing members of acpgp and aca and generalpartners of acp. acpgp, aca, robert atchinson and phillip gross disclaim beneficial ownership of the reported securitiesexcept to the extent of their pecuniary interest therein.


Filed on 2010-04-07 by Adage Capital Partners Gp Llc SEC CIK 1165408 Form 4

Accession 0000902664-10-002388.txt Sec File: edgar/data/1165408/0000902664-10-002388-index.htm

2010-04-05 Adage Capital Partners Gp Llc (CIK 1165408) through See Footnote

Invested in Cardiome Pharma Corp sold 500000 shares at $7.7601 remaining shares owned 7350000

Common Shares No Par Value Cardiome Pharma Corp Crme Transaction code: S Open market or private sale of securities

f1 adage capital partners gp, l.l.c., a delaware limited liability company ("acpgp"), serves as the general partner of adagecapital partners, l.p. (the "fund"), and as such has discretion over the portfolio securities beneficially owned by thefund. adage capital advisors, l.l.c., a delaware limited liability company ("aca"), is the managing member of acpgp anddirects acpgp's operations. robert atchinson and phillip gross are the managing members of acpgp and aca and generalpartners of acp. acpgp, aca, robert atchinson and phillip gross disclaim beneficial ownership of the reported securitiesexcept to the extent of their pecuniary interest therein.


Filed on 2009-04-13 by Adage Capital Partners Gp Llc SEC CIK 1165408 Form 4

Accession 0000902664-09-001546.txt Sec File: edgar/data/1165408/0000902664-09-001546-index.htm

2009-04-09 Adage Capital Partners Gp Llc (CIK 1165408) through See Footnote

Invested in Cardiome Pharma Corp bought 1000000 shares at $3.9195 remaining shares owned 7850000

Common Shares No Par Value Cardiome Pharma Corp Crme Transaction code: P Open market or private purchase of securities

f1 adage capital partners gp, l.l.c., a delaware limited liability company ("acpgp"), serves as the general partner of adagecapital partners, l.p. (the "fund"), and as such has discretion over the portfolio securities beneficially owned by thefund. adage capital advisors, l.l.c., a delaware limited liability company ("aca"), is the managing member of acpgp anddirects acpgp's operations. robert atchinson and phillip gross are the managing members of acpgp and aca and generalpartners of acp. acpgp, aca, robert atchinson and phillip gross disclaim beneficial ownership of the reported securitiesexcept to the extent of their pecuniary interest therein.