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 Fund Type: INSTITUTION Report Date: 2008-08-14 Current Value: $1,154,427,204 Total Performance: -7.19 %
 
Worst Move: Baker Bros Advisors Llc potentially lost $-2,908,814 on changes made with Auxilium Pharmaceuticals Inc (AUXL) buying shares when price went down.
Best Move: Baker Bros Advisors Llc potentially made $617,584 on changes made with Micromet Ag (MITI) buying shares when price went up.
Good Save: Baker Bros Advisors Llc potentially saved $8,727,384 on changes made with Celgene Corp (CELG) selling shares when price went down.
Missed Move: Baker Bros Advisors Llc potentially missed $-154,703 on changes made with Pharmacyclics Inc(PCYC) selling shares when price went up.
 
 
   

Baker Bros Advisors Llc Details

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Stock Country Symbol Industry Current Shares Current Value Value Chng. Return Activity Shares Chng. Shares Chg.% Results
Acadia Pharmaceuticals Inc (ACAD) US ACAD Medical-Drugs 2,798,951 $6,717,482 $-2,267,150 -25.23 % Added More 247,489 9.69 $-200,466
Acorda Therapeutics Inc (ACOR) US ACOR Medical-Biomedical ... 1,322,862 $38,402,684 $277,801 0.72 % Added More 37,187 2.89 $7,809
Adolor Corp (ADLR) US ADLR Medical-Drugs 254,515 $776,271 $-96,716 -11.07 % Sold Some -406 -0.15 $154
Alkermes Inc (ALKS) US ALKS Drug Delivery Syst ... 179,327 $2,447,814 $-462,664 -15.89 % Sold Some -653,710 -78.47 $1,686,572
Allos Therapeutics Inc (ALTH) US ALTH Therapeutics 11,248,621 $99,887,754 $-10,348,731 -9.38 % Added More 1,385,556 14.04 $-1,274,712
Alsius Corp (ALUS) US ALUS Medical Instrument ... 64,850 $94,033 $-36,965 -28.21 % No Change - - -
Altus Pharmaceuticals Inc (ALTU) US ALTU Therapeutics 40,477 $64,358 $-28,334 -30.56 % No Change - - -
Amicus Therapeutics Inc (FOLD) US FOLD Medical-Drugs 1,390,368 $19,479,056 $-4,018,164 -17.10 % Sold Some -2,294 -0.16 $6,630
Amylin Pharmaceuticals Inc (AMLN) US AMLN Therapeutics None - - - % Sold All -16,153 -100.00 $211,927
Ap Pharma Inc (APPA) US APPA Drug Delivery Syst ... 1,512,446 $2,238,420 $75,622 3.49 % Sold Some -2,731 -0.18 $-137
Ardea Biosciences Inc (RDEA) US RDEA Medical-Drugs 3,653,765 $50,896,946 $-2,776,861 -5.17 % Added More 410,611 12.66 $-312,064
Arena Pharmaceuticals Inc (ARNA) US ARNA Medical-Biomedical ... 27,246 $157,209 $-21,524 -12.04 % Sold Some -684 -2.44 $540
Array Biopharma Inc (ARRY) US ARRY Medical-Drugs 214,219 $1,424,556 $-267,774 -15.82 % Sold Some -47,709 -18.21 $59,636
Atherogenics Inc (AGIX) US AGIX Therapeutics 24,471 $9,299 $-11,012 -54.21 % Sold Some -886 -3.49 $399
Autoimmune Inc (AIMM.PK) US AIMM.PK Medical-Biomedical ... 26,100 $41,760 $-9,396 -18.36 % No Change - - -
Auxilium Pharmaceuticals Inc (AUXL) US AUXL Medical-Drugs 3,249,563 $120,363,814 $-14,298,077 -10.61 % Added More 661,094 25.53 $-2,908,814
Biocryst Pharmaceuticals Inc (BCRX) US BCRX Medical-Biomedical ... 5,918,411 $20,359,334 $1,716,339 9.20 % No Change - - -
Biomarin Pharmaceutical Inc (BMRN) US BMRN Therapeutics 71,021 $2,025,519 $75,282 3.86 % Added More 68,683 2937.68 $72,804
Cadence Pharmaceuticals Inc (CADX) US CADX Medical-Drugs 165,784 $1,621,368 $-14,921 -0.91 % Sold Some -316 -0.19 $28
Celgene Corp (CELG) US CELG Medical-Biomedical ... 1,127,593 $76,101,252 $-10,734,685 -12.36 % Sold Some -916,742 -44.84 $8,727,384
Cerus Corp (CERS) US CERS Medical Products None - - - % Sold All -19,136 -100.00 $5,358
Chelsea Therapeutics Intl Ltd (CHTP) US CHTP Medical-Drugs 1,136,263 $5,204,085 $-1,068,087 -17.02 % Sold Some -1,218 -0.10 $1,145
Critical Therapeutics Inc (CRTX) US CRTX Therapeutics 1,124,474 $258,629 $-89,958 -25.80 % Sold Some -3,007 -0.26 $241
Curagen Corp (CRGN) US CRGN Medical-Biomedical ... 156,013 $148,212 $1,560 1.06 % New Holding 156,013 100.00 $1,560
Cyclacel Pharmaceuticals Inc (CYCC) US CYCC Therapeutics 191,186 $225,599 $-89,857 -28.48 % Sold Some -68,700 -26.43 $32,289
Cytokinetics Inc (CYTK) US CYTK Medical-Biomedical ... 1,707,673 $8,470,058 $102,460 1.22 % Sold Some -4,191 -0.24 $-251
Dendreon Corp (DNDN) US DNDN Therapeutics 134,423 $778,309 $-16,131 -2.03 % Sold Some -285 -0.21 $34
Depomed Inc (DEPO) US DEPO Drug Delivery Syst ... 537,217 $2,304,661 $42,977 1.90 % Sold Some -1,006 -0.18 $-80
Genelabs Technologies Inc (GNLB) US GNLB Medical-Biomedical ... 154,937 $88,314 $15,494 21.27 % Sold Some -600,242 -79.48 $-60,024
Genomic Health Inc (GHDX) US GHDX Medical-Biomedical ... 5,200,387 $114,252,502 $-12,740,948 -10.03 % Added More 407,297 8.49 $-997,878
Halozyme Therapeutics Inc (HALO) US HALO Medical-Biomedical ... 3,304,796 $24,191,107 $-1,189,727 -4.68 % Added More 435,621 15.18 $-156,824
Icagen Inc (ICGN) US ICGN Medical-Drugs 59,473 $83,262 $-3,568 -4.10 % No Change - - -
Immunogen Inc (IMGN) US IMGN Medical-Biomedical ... 502,734 $2,443,287 $-392,133 -13.82 % Added More 223,556 80.07 $-174,374
Immunomedics Inc (IMMU) US IMMU Medical-Biomedical ... 75,244 $159,517 $-11,287 -6.60 % Sold Some -49,756 -39.80 $7,463
Incyte Corp (INCY) US INCY Medical-Biomedical ... 9,017,432 $86,837,870 $-5,500,634 -5.95 % No Change - - -
Indevus Pharmaceuticals Inc (IDEV) US IDEV Medical-Drugs 1,572,883 $3,114,308 $-62,915 -1.98 % Added More 403,154 34.46 $-16,126
Inhibitex Inc (INHX) US INHX Medical-Biomedical ... 155,964 $93,578 $7,798 9.09 % New Holding 155,964 100.00 $7,798
Inspire Pharmaceuticals Inc (ISPH) US ISPH Therapeutics 519,241 $2,295,045 $-10,385 -0.45 % Sold Some -978 -0.18 $20
Intermune Inc (ITMN) US ITMN Medical-Biomedical ... 1,427,494 $26,465,739 $913,596 3.57 % Sold Some -147,067 -9.34 $-94,123
Isis Pharmaceuticals Calif (ISIS) US ISIS Therapeutics 18,859 $321,735 $-36,586 -10.21 % No Change - - -
Kosan Biosciences Inc (KOSN) US KOSN Medical-Biomedical ... None - - - % Sold All -2,258,059 -100.00
Medarex Inc (MEDX) US MEDX Therapeutics 312,834 $2,158,555 $-613,155 -22.12 % Sold Some -365,208 -53.86 $715,808
Metabasis Therapeutics Inc (MBRX) US MBRX Medical-Biomedical ... 2,290,668 $3,665,069 $366,507 11.11 % Sold Some -43,798 -1.87 $-7,008
Micromet Ag (MITI) DE MITI Medical-Biomedical ... 2,689,114 $14,978,365 $3,253,828 27.75 % Added More 510,400 23.42 $617,584
Myriad Genetics Inc (MYGN) US MYGN Medical-Biomedical ... 349,528 $22,474,650 $-562,740 -2.44 % Sold Some -292,948 -45.59 $471,646
Neopharm Inc (NEOL) US NEOL Therapeutics None - - - % Sold All -35,938 -100.00 $-3,953
Neose Technologies Inc (NTEC) US NTEC Medical-Biomedical ... 2,251,191 $832,941 $45,024 5.71 % No Change - - -
Neurocrine Biosciences Inc (NBIX) US NBIX Therapeutics 50,000 $297,500 $62,500 26.59 % New Holding 50,000 100.00 $62,500
Neurogen Corp (NRGN) US NRGN Therapeutics 5,147,078 $1,647,065 $-411,766 -20.00 % No Change - - -
Onyx Pharmaceuticals Inc (ONXX) US ONXX Therapeutics 150,574 $5,745,904 $-998,306 -14.80 % Sold Some -242 -0.16 $1,604
Optimer Pharmaceuticals Inc (OPTR) US OPTR Medical-Biomedical ... 1,149,981 $9,176,848 $-1,287,979 -12.30 % Sold Some -127,519 -9.98 $142,821
Osi Pharmaceuticals Inc (OSIP) US OSIP Medical-Drugs 66,344 $3,193,800 $-281,962 -8.11 % Sold Some -209 -0.31 $888
Pdl Biopharma Inc (PDLI) US PDLI Medical-Biomedical ... 10,891 $128,623 $-1,416 -1.08 % New Holding 10,891 100.00 $-1,416
Pharmacyclics Inc (PCYC) US PCYC Therapeutics None - - - % Sold All -322,298 -100.00 $-154,703
Pharmasset Inc (VRUS) US VRUS Medical-Drugs 52,747 $1,068,654 $-50,110 -4.47 % Sold Some -118 -0.22 $112
Pozen Inc (POZN) US POZN Medical-Drugs 1,794,694 $19,239,120 $-3,876,539 -16.77 % Added More 311,754 21.02 $-673,389
Progenics Pharmaceuticals Inc (PGNX) US PGNX Therapeutics 961,306 $13,602,480 $624,849 4.81 % Added More 702,806 271.87 $456,824
Rigel Pharmaceuticals Inc (RIGL) US RIGL Medical-Drugs 55,560 $1,286,214 $-37,781 -2.85 % Sold Some -140 -0.25 $95
Salix Pharmaceuticals Ltd (SLXP) US SLXP Medical-Drugs 1,587,349 $10,698,732 $-3,349,306 -23.84 % Added More 60,405 3.95 $-127,455
Seattle Genetics Inc (SGEN) US SGEN Medical-Biomedical ... 12,912,124 $139,063,575 $-20,272,035 -12.72 % No Change - - -
Sequenom Inc (SQNM) US SQNM Medical-Biomedical ... 24,953 $571,424 $37,430 7.00 % New Holding 24,953 100.00 $37,430
Siga Technologies Inc (SIGA) US SIGA Medical-Drugs 932,837 $3,152,989 $867,538 37.95 % Sold Some -10,951 -1.16 $-10,184
Sirtris Pharmaceuticals Inc (SIRT) US SIRT Medical-Drugs None - - - % Sold All -13,843 -100.00
Spectrum Pharmaceuticals Inc (SPPI) US SPPI Therapeutics 421,349 $707,866 $-12,640 -1.75 % Sold Some -159,162 -27.41 $4,775
Supergen Inc (SUPG) US SUPG Medical-Biomedical ... 1,112,917 $1,791,796 $-367,263 -17.01 % Sold Some -26,932 -2.36 $8,888
Symyx Technologies (SMMX) US SMMX Chemicals-Specialt ... 325,442 $3,544,063 $-35,799 -1.00 % Sold Some -531 -0.16 $58
Tapestry Pharmaceuticals Inc (TPPH) US TPPH Therapeutics 1,939,453 % Sold Some -60,547 -3.02
Threshold Pharmaceuticals Inc (THLD) US THLD Therapeutics 2,263,600 $701,716 $-67,908 -8.82 % No Change - - -
Torreypines Therapeutics Inc (TPTX) US TPTX Medical-Biomedical ... 204,452 $126,760 $-47,024 -27.05 % Sold Some -13 0.00 $3
Trimeris Inc (TRMS) US TRMS Therapeutics 3,461,175 $13,498,583 $-1,903,646 -12.35 % No Change - - -
Vanda Pharmaceuticals Inc (VNDA) US VNDA Therapeutics 155,942 $163,739 $-37,426 -18.60 % New Holding 155,942 100.00 $-37,426
Vertex Pharmaceuticals Inc (VRTX) US VRTX Medical-Biomedical ... 66,262 $1,696,307 $-289,565 -14.58 % Added More 24,650 59.23 $-107,721
Via Pharmaceuticals Inc (VIAP) US VIAP Therapeutics 102,881 $175,927 $-2,058 -1.15 % No Change - - -
Viropharma Inc (VPHM) US VPHM Medical-Drugs 7,546,147 $107,985,364 $5,508,687 5.37 % Sold Some -18,662 -0.24 $-13,623
Xenoport Inc (XNPT) US XNPT Medical-Drugs 1,048,399 $50,207,828 $-2,442,770 -4.63 % Sold Some -123,844 -10.56 $288,557
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Listed 75 holdings.
   
 
Note: All amounts are based on price of stock at date reported versus the current price! They do not represent actual profit/loss!
There has been no adjustmentsfor splits!
Note: All amounts in USD, converted using Intrabank Exchange Rate on Date Reported/Today
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