| Filed | As-Of/On | Form | Fullname | Fund Class | Shares | Activity | Shares Change | Shares Pct. Change | Hypothetical Old Value | Hypothetical New Value | Hypothetical Value Chg. | Hypotheticals Return |
Hypotheticals Results |
Director |
Other |
Ten Pct |
Officer |
Officer Title |
News Article |
History |
|---|
| 2009-11-19 | 2009-09-30 | 13F-HR | Advent Capital Management | Institution | 115,500 | Added More | 65,500 | 131.00 % | $1,273,965 | $1,273,965 | $0 | 0.00 % | $0 | | | | | | News Article | History of Advent Capital Management Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-19 | 2009-09-30 | 13F-HR/A | Royal Bank Of Canada | Institution | | Sold All | -500 | -100 % | | | | 0.00 % | $0 | | | | | | News Article | History of Royal Bank Of Canada Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-18 | 2009-09-30 | 13F-HR | Jane Street Holding Llc | Institution | 16,959 | Added More | 3,767 | 28.55 % | $189,941 | $187,058 | $-2,883 | -1.51 % | $-640 | | | | | | News Article | History of Jane Street Holding Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-17 | 2009-09-30 | 13F-HR/A | Amvescap Plc | Institution | 1,014,998 | Added More | 53,451 | 5.55 % | $11,286,778 | $11,195,428 | $-91,350 | -0.80 % | $-4,811 | | | | | | News Article | History of Amvescap Plc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-17 | 2009-09-30 | 13F-HR/A | Credit Suisse First Boston | Institution | 45,491 | Sold Some | -92,767 | -67.09 % | $505,860 | $501,766 | $-4,094 | -0.80 % | $8,349 | | | | | | News Article | History of Credit Suisse First Boston Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-17 | 2009-09-30 | 13F-HR | Garrison Bradford And Associates Inc | Institution | 30,500 | No Change | 0 | 0 % | $339,160 | $336,415 | $-2,745 | -0.80 % | $0 | | | | | | News Article | History of Garrison Bradford And Associates Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-17 | 2009-09-30 | 13F-HR | Rothschild Asset Management Inc | Institution | 779,385 | Sold Some | -26,822 | -3.32 % | $8,666,761 | $8,596,617 | $-70,145 | -0.80 % | $2,414 | | | | | | News Article | History of Rothschild Asset Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-17 | 2009-09-30 | 13F-HR | Wells Fargo And Co | Institution | 436,725 | Sold Some | -68,331 | -13.52 % | $4,856,382 | $4,817,077 | $-39,305 | -0.80 % | $6,150 | | | | | | News Article | History of Wells Fargo And Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | American International Group Inc | Institution | 76,197 | Sold Some | -692 | -0.89 % | $1,021,040 | $840,453 | $-180,587 | -17.68 % | $1,640 | | | | | | News Article | History of American International Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Aqr Capital Management Llc | Institution | 72,503 | New Holding | 72,503 | 100 % | $971,540 | $799,708 | $-171,832 | -17.68 % | $-171,832 | | | | | | News Article | History of Aqr Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Bam Management Llc | No Data | 81,930 | Added More | 51,880 | 172.64 % | $1,097,862 | $903,688 | $-194,174 | -17.68 % | $-122,956 | | | | | | News Article | History of Bam Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Chilton Capital Management Advisors Inc | Institution | 61,540 | Sold Some | -6,050 | -8.95 % | $824,636 | $678,786 | $-145,850 | -17.68 % | $14,339 | | | | | | News Article | History of Chilton Capital Management Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Chilton Capital Management L P | Institution | 129,418 | Added More | 4,823 | 3.87 % | $1,734,201 | $1,427,481 | $-306,721 | -17.68 % | $-11,431 | | | | | | News Article | History of Chilton Capital Management L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Citadel L P | Institution | 36,449 | Added More | 35,702 | 4779.38 % | $488,417 | $402,032 | $-86,384 | -17.68 % | $-84,614 | | | | | | News Article | History of Citadel L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Dafna Capital Management Llc | Institution | 472,960 | Sold Some | -216,517 | -31.40 % | $6,337,664 | $5,216,749 | $-1,120,915 | -17.68 % | $513,145 | | | | | | News Article | History of Dafna Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Diker Management Llc | Institution | 493,719 | Sold Some | -109,490 | -18.15 % | $6,615,835 | $5,445,721 | $-1,170,114 | -17.68 % | $259,491 | | | | | | News Article | History of Diker Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Employees Retirement System Of Texas | Institution | 133,000 | Sold Some | -71,400 | -34.93 % | $1,782,200 | $1,466,990 | $-315,210 | -17.68 % | $169,218 | | | | | | News Article | History of Employees Retirement System Of Texas Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Fidelity International Ltd | Institution | | Sold All | -3,580 | -100 % | | | | -17.68 % | $8,485 | | | | | | News Article | History of Fidelity International Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Fifth Third Bancorp | Institution | 175 | Sold Some | -76 | -30.27 % | $2,345 | $1,930 | $-415 | -17.68 % | $180 | | | | | | News Article | History of Fifth Third Bancorp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Fmr Corp | Institution | 14,718,917 | Added More | 2,945 | 0.02 % | $197,233,488 | $162,349,655 | $-34,883,833 | -17.68 % | $-6,980 | | | | | | News Article | History of Fmr Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Ing Groep Nv | Institution | 35,720 | Sold Some | -51,480 | -59.03 % | $478,648 | $393,992 | $-84,656 | -17.68 % | $122,008 | | | | | | News Article | History of Ing Groep Nv Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Leuthold Weeden Capital Management Llc | Institution | 485,855 | Added More | 28,876 | 6.31 % | $6,510,457 | $5,358,981 | $-1,151,476 | -17.68 % | $-68,436 | | | | | | News Article | History of Leuthold Weeden Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Loomis Sayles And Co L P | Institution | 144,903 | Sold Some | -812 | -0.55 % | $1,941,700 | $1,598,280 | $-343,420 | -17.68 % | $1,924 | | | | | | News Article | History of Loomis Sayles And Co L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Madison Square Investors Llc | No Data | 37,646 | Sold Some | -46,611 | -55.32 % | $504,456 | $415,235 | $-89,221 | -17.68 % | $110,468 | | | | | | News Article | History of Madison Square Investors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Morgan Stanley | Institution | 1,245,412 | Added More | 242,482 | 24.17 % | $16,688,521 | $13,736,894 | $-2,951,626 | -17.68 % | $-574,682 | | | | | | News Article | History of Morgan Stanley Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Northern Trust Co Of Connecticut | Institution | | Sold All | -40,575 | -100 % | | | | -17.68 % | $96,163 | | | | | | News Article | History of Northern Trust Co Of Connecticut Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Northern Trust Corp | Institution | 1,121,233 | Added More | 64,848 | 6.13 % | $15,024,522 | $12,367,200 | $-2,657,322 | -17.68 % | $-153,690 | | | | | | News Article | History of Northern Trust Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR/A | Oppenheimer Funds Inc | Institution | 3,010,600 | Sold Some | -140,860 | -4.46 % | $40,342,040 | $33,206,918 | $-7,135,122 | -17.68 % | $333,838 | | | | | | News Article | History of Oppenheimer Funds Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Perimeter Capital Partners Llc | Institution | 400,843 | Added More | 119,843 | 42.64 % | $5,371,296 | $4,421,298 | $-949,998 | -17.68 % | $-284,028 | | | | | | News Article | History of Perimeter Capital Partners Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR/A | Rafferty Asset Management Llc | Institution | 19,532 | Sold Some | -9,411 | -32.51 % | $261,729 | $215,438 | $-46,291 | -17.68 % | $22,304 | | | | | | News Article | History of Rafferty Asset Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Sac Capital Advisors Lp | No Data | 39,012 | New Holding | 39,012 | 100 % | $522,761 | $430,302 | $-92,458 | -17.68 % | $-92,458 | | | | | | News Article | History of Sac Capital Advisors Lp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Shaw D E And Co Inc | Institution | 78,887 | Sold Some | -196,189 | -71.32 % | $1,057,086 | $870,124 | $-186,962 | -17.68 % | $464,968 | | | | | | News Article | History of Shaw D E And Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Two Sigma Investments Llc | Institution | 13,381 | New Holding | 13,381 | 100 % | $179,305 | $147,592 | $-31,713 | -17.68 % | $-31,713 | | | | | | News Article | History of Two Sigma Investments Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Ubs Global Asset Management Americas Inc | Institution | 507,700 | Added More | 3,700 | 0.73 % | $6,803,180 | $5,599,931 | $-1,203,249 | -17.68 % | $-8,769 | | | | | | News Article | History of Ubs Global Asset Management Americas Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-16 | 2009-09-30 | 13F-HR | Us Bancorp De | Institution | 400 | No Change | 0 | 0 % | $5,360 | $4,412 | $-948 | -17.68 % | $0 | | | | | | News Article | History of Us Bancorp De Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Ameriprise Financial Inc | Institution | 109,123 | Sold Some | -49,425 | -31.17 % | $1,430,603 | $1,203,627 | $-226,976 | -15.86 % | $102,804 | | | | | | News Article | History of Ameriprise Financial Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Axa | Institution | 403,914 | Sold Some | -169,271 | -29.53 % | $5,295,313 | $4,455,171 | $-840,141 | -15.86 % | $352,084 | | | | | | News Article | History of Axa Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Barclays Plc | Institution | 237,394 | Added More | 115,611 | 94.93 % | $3,112,235 | $2,618,456 | $-493,780 | -15.86 % | $-240,471 | | | | | | News Article | History of Barclays Plc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Batterymarch Financial Management Inc | Institution | 200,319 | Sold Some | -28,590 | -12.48 % | $2,626,182 | $2,209,519 | $-416,664 | -15.86 % | $59,467 | | | | | | News Article | History of Batterymarch Financial Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Bnp Paribas Arbitrage Sa | Institution | 33,590 | Added More | 19,984 | 146.87 % | $440,365 | $370,498 | $-69,867 | -15.86 % | $-41,567 | | | | | | News Article | History of Bnp Paribas Arbitrage Sa Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Capital Fund Management S A | Institution | 1,692 | New Holding | 1,692 | 100 % | $22,182 | $18,663 | $-3,519 | -15.86 % | $-3,519 | | | | | | News Article | History of Capital Fund Management S A Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Caxton Associates Llc | Institution | 29,872 | Added More | 7,036 | 30.81 % | $391,622 | $329,488 | $-62,134 | -15.86 % | $-14,635 | | | | | | News Article | History of Caxton Associates Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Clearbridge Advisors Llc | Institution | 2,255,838 | Sold Some | -93,414 | -3.97 % | $29,574,036 | $24,881,893 | $-4,692,143 | -15.86 % | $194,301 | | | | | | News Article | History of Clearbridge Advisors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Dekabank Deutsche Girozentrale | No Data | 177,000 | No Change | 0 | 0 % | $2,320,470 | $1,952,310 | $-368,160 | -15.86 % | $0 | | | | | | News Article | History of Dekabank Deutsche Girozentrale Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Fortaleza Asset Management Inc | Institution | 39,495 | Sold Some | -28,925 | -42.27 % | $517,779 | $435,630 | $-82,150 | -15.86 % | $60,164 | | | | | | News Article | History of Fortaleza Asset Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Gartmore Mutual Fund Capital Trust | Institution | 989 | Sold Some | -70,491 | -98.61 % | $12,966 | $10,909 | $-2,057 | -15.86 % | $146,621 | | | | | | News Article | History of Gartmore Mutual Fund Capital Trust Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Geode Capital Management Llc | Institution | 225,928 | Sold Some | -132,797 | -37.01 % | $2,961,916 | $2,491,986 | $-469,930 | -15.86 % | $276,218 | | | | | | News Article | History of Geode Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Goldman Sachs Group Inc | Institution | 599,406 | Sold Some | -256,825 | -29.99 % | $7,858,213 | $6,611,448 | $-1,246,764 | -15.86 % | $534,196 | | | | | | News Article | History of Goldman Sachs Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Hambrecht And Quist Capital Management Llc | Institution | 153,000 | New Holding | 153,000 | 100 % | $2,005,830 | $1,687,590 | $-318,240 | -15.86 % | $-318,240 | | | | | | News Article | History of Hambrecht And Quist Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Ironbridge Capital Management Llc | Institution | 1,324,299 | Added More | 277,718 | 26.53 % | $17,361,560 | $14,607,018 | $-2,754,542 | -15.86 % | $-577,653 | | | | | | News Article | History of Ironbridge Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Jacobs Levy Equity Management Inc | Institution | 510,616 | Sold Some | -139,377 | -21.44 % | $6,694,176 | $5,632,094 | $-1,062,081 | -15.86 % | $289,904 | | | | | | News Article | History of Jacobs Levy Equity Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Los Angeles Capital Management And Equity Research Inc | Institution | 36,586 | New Holding | 36,586 | 100 % | $479,642 | $403,544 | $-76,099 | -15.86 % | $-76,099 | | | | | | News Article | History of Los Angeles Capital Management And Equity Research Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Managed Account Advisors Llc | Institution | 33,094 | Added More | 32,639 | 7173.40 % | $433,862 | $365,027 | $-68,836 | -15.86 % | $-67,889 | | | | | | News Article | History of Managed Account Advisors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Martingale Asset Management L P | Institution | 37,100 | Sold Some | -39,800 | -51.75 % | $486,381 | $409,213 | $-77,168 | -15.86 % | $82,784 | | | | | | News Article | History of Martingale Asset Management L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | N-Q | Met Investors Series Trust - Metaim Small Cap Growth Portfolio | Small-Cap Growth | 226,477 | Added More | 5,794 | 2.62 % | $2,969,113 | $2,498,041 | $-471,072 | -15.86 % | $-12,052 | | | | | | News Article | History of Met Investors Series Trust - Metaim Small Cap Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR/A | Neuberger Berman Group Llc | No Data | 15,255 | Sold Some | -3,518 | -18.73 % | $199,993 | $168,263 | $-31,730 | -15.86 % | $7,317 | | | | | | News Article | History of Neuberger Berman Group Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | New York State Common Retirement Fund | Institution | 30,780 | No Change | 0 | 0 % | $403,526 | $339,503 | $-64,022 | -15.86 % | $0 | | | | | | News Article | History of New York State Common Retirement Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Panagora Asset Management Inc | Institution | 4,743 | Sold Some | -237,769 | -98.04 % | $62,181 | $52,315 | $-9,865 | -15.86 % | $494,560 | | | | | | News Article | History of Panagora Asset Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Paradigm Asset Management Co Llc | Institution | | Sold All | -18,900 | -100 % | | | | -15.86 % | $39,312 | | | | | | News Article | History of Paradigm Asset Management Co Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Pergamon Offshore Advisors L P | Institution | | Sold All | -66,065 | -100 % | | | | -15.86 % | $137,415 | | | | | | News Article | History of Pergamon Offshore Advisors L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Price T Rowe Associates Inc | Institution | 58,785 | Added More | 9,300 | 18.79 % | $770,671 | $648,399 | $-122,273 | -15.86 % | $-19,344 | | | | | | News Article | History of Price T Rowe Associates Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Rbc Capital Markets Arbitrage S A | Institution | 12,236 | New Holding | 12,236 | 100 % | $160,414 | $134,963 | $-25,451 | -15.86 % | $-25,451 | | | | | | News Article | History of Rbc Capital Markets Arbitrage S A Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Rbc Dain Rauscher Inc | Institution | 245,078 | Added More | 12,715 | 5.47 % | $3,212,973 | $2,703,210 | $-509,762 | -15.86 % | $-26,447 | | | | | | News Article | History of Rbc Dain Rauscher Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Renaissance Technologies Corp | Institution | 469,414 | Added More | 458,814 | 4328.43 % | $6,154,018 | $5,177,636 | $-976,381 | -15.86 % | $-954,333 | | | | | | News Article | History of Renaissance Technologies Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Sei Trust Co | Institution | 33,800 | Added More | 29,260 | 644.49 % | $443,118 | $372,814 | $-70,304 | -15.86 % | $-60,861 | | | | | | News Article | History of Sei Trust Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Sg Americas Securities Llc | Institution | 75,124 | New Holding | 75,124 | 100 % | $984,876 | $828,618 | $-156,258 | -15.86 % | $-156,258 | | | | | | News Article | History of Sg Americas Securities Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Vanguard Group Inc | Institution | 5,785,105 | Added More | 113,923 | 2.00 % | $75,842,727 | $63,809,708 | $-12,033,018 | -15.86 % | $-236,960 | | | | | | News Article | History of Vanguard Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-13 | 2009-09-30 | 13F-HR | Wolverine Asset Management Llc | Institution | 8,108 | New Holding | 8,108 | 100 % | $106,296 | $89,431 | $-16,865 | -15.86 % | $-16,865 | | | | | | News Article | History of Wolverine Asset Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Allianz Global Investors Of America L P | Institution | 452,375 | Added More | 60,436 | 15.41 % | $6,061,825 | $4,989,696 | $-1,072,129 | -17.68 % | $-143,233 | | | | | | News Article | History of Allianz Global Investors Of America L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Allstate Insurance Co | Institution | 90,000 | No Change | 0 | 0 % | $1,206,000 | $992,700 | $-213,300 | -17.68 % | $0 | | | | | | News Article | History of Allstate Insurance Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Bank Of America Corp | Institution | 290,265 | Added More | 87,273 | 42.99 % | $3,889,551 | $3,201,623 | $-687,928 | -17.68 % | $-206,837 | | | | | | News Article | History of Bank Of America Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Barclays Global Investors Uk Holdings Ltd | Institution | 5,524,563 | Added More | 269,991 | 5.13 % | $74,029,144 | $60,935,930 | $-13,093,214 | -17.68 % | $-639,879 | | | | | | News Article | History of Barclays Global Investors Uk Holdings Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Barclays Global Investors Uk Holdings Ltd | Institution | 5,524,563 | Added More | 27,119 | 0.49 % | $74,029,144 | $60,935,930 | $-13,093,214 | -17.68 % | $-64,272 | | | | | | News Article | History of Barclays Global Investors Uk Holdings Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Chicago Equity Partners Llc | Institution | | Sold All | -27,650 | -100 % | | | | -17.68 % | $65,531 | | | | | | News Article | History of Chicago Equity Partners Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR/A | Cookson Peirce And Co Inc | Institution | | Sold All | -304,551 | -100 % | | | | -17.68 % | $721,786 | | | | | | News Article | History of Cookson Peirce And Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Corestates Capital Advisors Llc | No Data | 2,000 | New Holding | 2,000 | 100 % | $26,800 | $22,060 | $-4,740 | -17.68 % | $-4,740 | | | | | | News Article | History of Corestates Capital Advisors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Credit Suisse | Institution | 26,184 | New Holding | 26,184 | 100 % | $350,866 | $288,810 | $-62,056 | -17.68 % | $-62,056 | | | | | | News Article | History of Credit Suisse Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | First Quadrant L P | Institution | 23,400 | No Change | 0 | 0 % | $313,560 | $258,102 | $-55,458 | -17.68 % | $0 | | | | | | News Article | History of First Quadrant L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Fortis Investments Management Usa Inc | Institution | 24,034 | Sold Some | -29,283 | -54.92 % | $322,056 | $265,095 | $-56,961 | -17.68 % | $69,401 | | | | | | News Article | History of Fortis Investments Management Usa Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Franklin Resources Inc | Institution | 580,723 | Added More | 222,710 | 62.20 % | $7,781,688 | $6,405,375 | $-1,376,314 | -17.68 % | $-527,823 | | | | | | News Article | History of Franklin Resources Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Green Square Capital Management Llc | Institution | 20,100 | No Change | 0 | 0 % | $269,340 | $221,703 | $-47,637 | -17.68 % | $0 | | | | | | News Article | History of Green Square Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR/A | Ing Investment Management Co | Institution | 35,420 | Sold Some | -51,780 | -59.38 % | $474,628 | $390,683 | $-83,945 | -17.68 % | $122,719 | | | | | | News Article | History of Ing Investment Management Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Kbc Group Nv | Institution | 18,241 | Sold Some | -6,139 | -25.18 % | $244,429 | $201,198 | $-43,231 | -17.68 % | $14,549 | | | | | | News Article | History of Kbc Group Nv Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Merrill Lynch And Co Inc | Institution | 188,137 | Added More | 3,076 | 1.66 % | $2,521,036 | $2,075,151 | $-445,885 | -17.68 % | $-7,290 | | | | | | News Article | History of Merrill Lynch And Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Mfc Global Investment Management Usa Ltd | Institution | 92,474 | Added More | 8,554 | 10.19 % | $1,239,152 | $1,019,988 | $-219,163 | -17.68 % | $-20,273 | | | | | | News Article | History of Mfc Global Investment Management Usa Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Nomura Asset Management Co Ltd | Institution | 410,558 | Added More | 61,058 | 17.47 % | $5,501,477 | $4,528,455 | $-973,022 | -17.68 % | $-144,707 | | | | | | News Article | History of Nomura Asset Management Co Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Padco Advisors Ii Inc | Institution | 30,229 | Added More | 9,361 | 44.85 % | $405,069 | $333,426 | $-71,643 | -17.68 % | $-22,186 | | | | | | News Article | History of Padco Advisors Ii Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Padco Advisors Inc | Institution | 192,922 | Added More | 73,659 | 61.76 % | $2,585,155 | $2,127,930 | $-457,225 | -17.68 % | $-174,572 | | | | | | News Article | History of Padco Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Principal Financial Group Inc | Institution | 369,790 | No Change | 0 | 0 % | $4,955,186 | $4,078,784 | $-876,402 | -17.68 % | $0 | | | | | | News Article | History of Principal Financial Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Russell Frank Co | Institution | 262,083 | Added More | 51,084 | 24.21 % | $3,511,912 | $2,890,775 | $-621,137 | -17.68 % | $-121,069 | | | | | | News Article | History of Russell Frank Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Seger Elvekrog Inc | Institution | 12,000 | No Change | 0 | 0 % | $160,800 | $132,360 | $-28,440 | -17.68 % | $0 | | | | | | News Article | History of Seger Elvekrog Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Sovereign Asset Management Corp | Institution | 163,470 | Added More | 47,245 | 40.64 % | $2,190,498 | $1,803,074 | $-387,424 | -17.68 % | $-111,971 | | | | | | News Article | History of Sovereign Asset Management Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Strategic Investment Management | Institution | | Sold All | -22,884 | -100 % | | | | -17.68 % | $54,235 | | | | | | News Article | History of Strategic Investment Management Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Suffolk Capital Management Llc | Institution | 45,000 | No Change | 0 | 0 % | $603,000 | $496,350 | $-106,650 | -17.68 % | $0 | | | | | | News Article | History of Suffolk Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Suntrust Banks Inc | Institution | 183,846 | Sold Some | -963 | -0.52 % | $2,463,536 | $2,027,821 | $-435,715 | -17.68 % | $2,282 | | | | | | News Article | History of Suntrust Banks Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Susquehanna International Group Llp | Institution | 78,917 | Added More | 48,630 | 160.56 % | $1,057,488 | $870,455 | $-187,033 | -17.68 % | $-115,253 | | | | | | News Article | History of Susquehanna International Group Llp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Tewksbury Capital Management Ltd | Institution | 21,139 | New Holding | 21,139 | 100 % | $283,263 | $233,163 | $-50,099 | -17.68 % | $-50,099 | | | | | | News Article | History of Tewksbury Capital Management Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | United Services Automobile Association | Institution | 112,800 | Sold Some | -2,400 | -2.08 % | $1,511,520 | $1,244,184 | $-267,336 | -17.68 % | $5,688 | | | | | | News Article | History of United Services Automobile Association Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | Virginia Retirement Systems Et Al | Institution | 38,100 | No Change | 0 | 0 % | $510,540 | $420,243 | $-90,297 | -17.68 % | $0 | | | | | | News Article | History of Virginia Retirement Systems Et Al Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-09-30 | 13F-HR | World Asset Management Inc | Institution | 11,845 | No Change | 0 | 0 % | $158,723 | $130,650 | $-28,073 | -17.68 % | $0 | | | | | | News Article | History of World Asset Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-12 | 2009-08-31 | N-CSR | Satuit Capital Management Trust - Satuit Capital Small Cap Fund | No Data | 1,250 | New Holding | 1,250 | 100 % | $16,750 | $13,788 | $-2,963 | -17.68 % | $-2,963 | | | | | | News Article | History of Satuit Capital Management Trust - Satuit Capital Small Cap Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-10 | 2009-09-30 | 13F-HR | American Century Companies Inc | Institution | 132,309 | Sold Some | -192,346 | -59.24 % | $1,783,525 | $1,459,368 | $-324,157 | -18.17 % | $471,248 | | | | | | News Article | History of American Century Companies Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-10 | 2009-09-30 | 13F-HR | Citigroup Inc | Institution | 30,394 | Sold Some | -226,476 | -88.16 % | $409,711 | $335,246 | $-74,465 | -18.17 % | $554,866 | | | | | | News Article | History of Citigroup Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-10 | 2009-09-30 | 13F-HR | Comerica Bank | Institution | 35,266 | Sold Some | -23,811 | -40.30 % | $475,386 | $388,984 | $-86,402 | -18.17 % | $58,337 | | | | | | News Article | History of Comerica Bank Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-10 | 2009-09-30 | 13F-HR | J P Morgan Chase And Co | Institution | 231,088 | Sold Some | -156,701 | -40.40 % | $3,115,066 | $2,548,901 | $-566,166 | -18.17 % | $383,917 | | | | | | News Article | History of J P Morgan Chase And Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-10 | 2009-09-30 | 13F-HR | Sectoral Asset Management Inc | Institution | 2,000,713 | Sold Some | -473,475 | -19.13 % | $26,969,611 | $22,067,864 | $-4,901,747 | -18.17 % | $1,160,014 | | | | | | News Article | History of Sectoral Asset Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-10 | 2009-09-30 | 13F-HR | Tesseract Capital Llc | No Data | | Sold All | -1,215 | -100 % | | | | -18.17 % | $2,977 | | | | | | News Article | History of Tesseract Capital Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-10 | 2009-09-30 | 13F-HR | Ubs Ag | Institution | 56,581 | Added More | 7,235 | 14.66 % | $762,712 | $624,088 | $-138,623 | -18.17 % | $-17,726 | | | | | | News Article | History of Ubs Ag Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-10 | 2009-09-30 | 13F-HR | William Harris Investors Inc | Institution | 561,134 | Sold Some | -50,000 | -8.18 % | $7,564,086 | $6,189,308 | $-1,374,778 | -18.17 % | $122,500 | | | | | | News Article | History of William Harris Investors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-10 | 2009-03-31 | 13F-HR/A | Dlibj Asset Management Co Ltd | Institution | | Sold All | -250 | -100 % | | | | -18.17 % | $613 | | | | | | News Article | History of Dlibj Asset Management Co Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-10 | 2008-12-31 | 13F-HR/A | Dlibj Asset Management Co Ltd | Institution | 250 | New Holding | 250 | 100 % | $3,370 | $2,758 | $-613 | -18.17 % | $-613 | | | | | | News Article | History of Dlibj Asset Management Co Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-09 | 2009-09-30 | 13F-HR | Aberdeen Asset Management Plc | Institution | 58,101 | New Holding | 58,101 | 100 % | $789,012 | $640,854 | $-148,158 | -18.77 % | $-148,158 | | | | | | News Article | History of Aberdeen Asset Management Plc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-09 | 2009-09-30 | 13F-HR | Cadence Capital Management Llc | Institution | 378,280 | Added More | 32,050 | 9.25 % | $5,137,042 | $4,172,428 | $-964,614 | -18.77 % | $-81,728 | | | | | | News Article | History of Cadence Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-09 | 2009-09-30 | 13F-HR | Federated Investors Inc | Institution | 7,649,677 | Added More | 17,900 | 0.23 % | $103,882,614 | $84,375,937 | $-19,506,676 | -18.77 % | $-45,645 | | | | | | News Article | History of Federated Investors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-09 | 2009-09-30 | 13F-HR | Lee Munder Capital Group Llc | No Data | 87,249 | No Compare | | | $1,184,841 | $962,356 | $-222,485 | -18.77 % | | | | | | | News Article | History of Lee Munder Capital Group Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-09 | 2009-09-30 | 13F-HR | Numeric Investors Llc | Institution | 55,400 | Sold Some | -6,300 | -10.21 % | $752,332 | $611,062 | $-141,270 | -18.77 % | $16,065 | | | | | | News Article | History of Numeric Investors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Genworth Financial Inc | Institution | 39 | New Holding | 39 | 100 % | $525 | $430 | $-95 | -18.05 % | $-95 | | | | | | News Article | History of Genworth Financial Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Hartford Investment Management Co | Institution | 275,526 | Added More | 22,000 | 8.67 % | $3,708,580 | $3,039,052 | $-669,528 | -18.05 % | $-53,460 | | | | | | News Article | History of Hartford Investment Management Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Metlife Securities Inc | Institution | | Sold All | -36 | -100 % | | | | -18.05 % | $87 | | | | | | News Article | History of Metlife Securities Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Metropolitan Life Insurance Co | Institution | 83,865 | No Change | 0 | 0 % | $1,128,823 | $925,031 | $-203,792 | -18.05 % | $0 | | | | | | News Article | History of Metropolitan Life Insurance Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Pnc Financial Services Group Inc | Institution | 5,437 | Sold Some | -47,899 | -89.80 % | $73,182 | $59,970 | $-13,212 | -18.05 % | $116,395 | | | | | | News Article | History of Pnc Financial Services Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Sam Sustainable Asset Management Ltd | Institution | 3,000 | New Holding | 3,000 | 100 % | $40,380 | $33,090 | $-7,290 | -18.05 % | $-7,290 | | | | | | News Article | History of Sam Sustainable Asset Management Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Schwab Charles Investment Management Inc | Institution | 48,088 | Sold Some | -72,826 | -60.22 % | $647,264 | $530,411 | $-116,854 | -18.05 % | $176,967 | | | | | | News Article | History of Schwab Charles Investment Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Tcw Group Inc | Institution | 681,615 | Sold Some | -156,900 | -18.71 % | $9,174,538 | $7,518,213 | $-1,656,324 | -18.05 % | $381,267 | | | | | | News Article | History of Tcw Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Teachers Advisors Inc | Institution | 181,674 | Sold Some | -33,931 | -15.73 % | $2,445,332 | $2,003,864 | $-441,468 | -18.05 % | $82,452 | | | | | | News Article | History of Teachers Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Tiaa Cref Investment Management Llc | Institution | 587,202 | Sold Some | -126,351 | -17.70 % | $7,903,739 | $6,476,838 | $-1,426,901 | -18.05 % | $307,033 | | | | | | News Article | History of Tiaa Cref Investment Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Unionbancal Corp | Institution | 3,400 | No Change | 0 | 0 % | $45,764 | $37,502 | $-8,262 | -18.05 % | $0 | | | | | | News Article | History of Unionbancal Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Waddell And Reed Financial Inc | Institution | 1,789,550 | Added More | 250 | 0.01 % | $24,087,343 | $19,738,737 | $-4,348,607 | -18.05 % | $-608 | | | | | | News Article | History of Waddell And Reed Financial Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Campbell And Co Investment Adviser Llc | Institution | 93,884 | New Holding | 93,884 | 100 % | $1,272,128 | $1,035,541 | $-236,588 | -18.59 % | $-236,588 | | | | | | News Article | History of Campbell And Co Investment Adviser Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Cumberland Associates Llc | Institution | 170,000 | Sold Some | -40,000 | -19.04 % | $2,303,500 | $1,875,100 | $-428,400 | -18.59 % | $100,800 | | | | | | News Article | History of Cumberland Associates Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Old Mutual Asset Managers Uk Ltd | Institution | | Sold All | -118,028 | -100 % | | | | -18.59 % | $297,431 | | | | | | News Article | History of Old Mutual Asset Managers Uk Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Parametric Portfolio Associates | Institution | 38,961 | Added More | 2,448 | 6.70 % | $527,922 | $429,740 | $-98,182 | -18.59 % | $-6,169 | | | | | | News Article | History of Parametric Portfolio Associates Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Profund Advisors Llc | Institution | 16,332 | Added More | 680 | 4.34 % | $221,299 | $180,142 | $-41,157 | -18.59 % | $-1,714 | | | | | | News Article | History of Profund Advisors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Proshare Advisors Llc | Institution | 26,516 | Sold Some | -13,127 | -33.11 % | $359,292 | $292,471 | $-66,820 | -18.59 % | $33,080 | | | | | | News Article | History of Proshare Advisors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-08-31 | N-CSR | Claymore Exchange Traded Fund Trust - Claymoreocean Tomo Growth Etf | Multi-Cap Growth | 208 | Added More | 25 | 13.66 % | $2,818 | $2,294 | $-524 | -18.59 % | $-63 | | | | | | News Article | History of Claymore Exchange Traded Fund Trust - Claymoreocean Tomo Growth Etf Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-08-31 | N-CSR | Claymore Exchange Traded Fund Trust - Claymoreocean Tomo Patent Etf | Specialty & Misc | 103 | No Change | 0 | 0 % | $1,396 | $1,136 | $-260 | -18.59 % | $0 | | | | | | News Article | History of Claymore Exchange Traded Fund Trust - Claymoreocean Tomo Patent Etf Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-09-30 | 13F-HR | Atlas Browninc | Institution | 20,100 | New Holding | 20,100 | 100 % | $252,456 | $221,703 | $-30,753 | -12.18 % | $-30,753 | | | | | | News Article | History of Atlas Browninc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-09-30 | 13F-HR | Gw Capital Management Incco | Institution | 30,700 | Added More | 100 | 0.32 % | $385,592 | $338,621 | $-46,971 | -12.18 % | $-153 | | | | | | News Article | History of Gw Capital Management Incco Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-09-30 | 13F-HR | Symphony Asset Management Llc | Institution | 581,749 | Added More | 229,457 | 65.13 % | $7,306,767 | $6,416,691 | $-890,076 | -12.18 % | $-351,069 | | | | | | News Article | History of Symphony Asset Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-08-31 | N-CSRS | Gmo Trust - Gmo Value Fund | Multi-Cap Value | | Sold All | -200 | -100 % | | | | -12.18 % | $306 | | | | | | News Article | History of Gmo Trust - Gmo Value Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-08-31 | N-CSR | Legg Mason Partners Equity Trust - Legg Mason Partners Aggressive Growth Fund | Multi-Cap Growth | 952,000 | New Holding | 952,000 | 100 % | $11,957,120 | $10,500,560 | $-1,456,560 | -12.18 % | $-1,456,560 | | | | | | News Article | History of Legg Mason Partners Equity Trust - Legg Mason Partners Aggressive Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-08-31 | N-CSR | Ssga Funds - Ssga Enhanced Small Cap Fund | Small-Cap Core | 6,411 | Added More | 211 | 3.40 % | $80,522 | $70,713 | $-9,809 | -12.18 % | $-323 | | | | | | News Article | History of Ssga Funds - Ssga Enhanced Small Cap Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-03 | 2009-09-30 | 13F-HR | M And T Bank Corp | Institution | 350 | No Change | 0 | 0 % | $4,431 | $3,861 | $-571 | -12.87 % | $0 | | | | | | News Article | History of M And T Bank Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-03 | 2009-09-30 | 13F-HR | Prudential Financial Inc | Institution | 723,545 | Sold Some | -205,200 | -22.09 % | $9,160,080 | $7,980,701 | $-1,179,378 | -12.87 % | $334,476 | | | | | | News Article | History of Prudential Financial Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-02 | 2009-09-30 | 13F-HR | Dowling And Yahnke Inc | Institution | 778,386 | No Change | 0 | 0 % | $9,636,419 | $8,585,598 | $-1,050,821 | -10.90 % | $0 | | | | | | News Article | History of Dowling And Yahnke Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-02 | 2009-09-30 | 13F-HR | Emerald Advisers Inc | Institution | 179,610 | New Holding | 179,610 | 100 % | $2,223,572 | $1,981,098 | $-242,474 | -10.90 % | $-242,474 | | | | | | News Article | History of Emerald Advisers Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-02 | 2009-09-30 | 13F-HR | Emerald Mutual Fund Advisers Trust | Institution | 81,480 | New Holding | 81,480 | 100 % | $1,008,722 | $898,724 | $-109,998 | -10.90 % | $-109,998 | | | | | | News Article | History of Emerald Mutual Fund Advisers Trust Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-02 | 2009-09-30 | 13F-HR | Ghp Investment Advisors Inc | Institution | | Sold All | -250 | -100 % | | | | -10.90 % | $338 | | | | | | News Article | History of Ghp Investment Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-02 | 2009-08-31 | N-CSRS | Fidelity Select Portfolios - Technology Portfolio | Science & Tech | 813,310 | Sold Some | -34,600 | -4.08 % | $10,068,778 | $8,970,809 | $-1,097,969 | -10.90 % | $46,710 | | | | | | News Article | History of Fidelity Select Portfolios - Technology Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-09-30 | 13F-HR | General Electric Co | Institution | 210,608 | No Change | 0 | 0 % | $2,668,403 | $2,323,006 | $-345,397 | -12.94 % | $0 | | | | | | News Article | History of General Electric Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-09-30 | 13F-HR | Oxford Asset Management | Institution | | Sold All | -10,233 | -100 % | | | | -12.94 % | $16,782 | | | | | | News Article | History of Oxford Asset Management Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-09-30 | 13F-HR/A | Perkins Capital Management Inc | Institution | 246,916 | Sold Some | -8,634 | -3.37 % | $3,128,426 | $2,723,483 | $-404,942 | -12.94 % | $14,160 | | | | | | News Article | History of Perkins Capital Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-09-30 | 13F-HR | Tocqueville Asset Management Lp | Institution | 1,440,220 | Added More | 31,725 | 2.25 % | $18,247,587 | $15,885,627 | $-2,361,961 | -12.94 % | $-52,029 | | | | | | News Article | History of Tocqueville Asset Management Lp Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Fidelity Advisor Series I - Growth Opportunities Fund | Large-Cap Core | 1,002,200 | Added More | 225,800 | 29.08 % | $12,697,874 | $11,054,266 | $-1,643,608 | -12.94 % | $-370,312 | | | | | | News Article | History of Fidelity Advisor Series I - Growth Opportunities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Fidelity Commonwealth Trust - Fidelity Nasdaq Composite Index Tracking Stock | Specialty & Misc | 3,906 | No Compare | | | $49,489 | $43,083 | $-6,406 | -12.94 % | | | | | | | News Article | History of Fidelity Commonwealth Trust - Fidelity Nasdaq Composite Index Tracking Stock Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-CSRS | Fidelity Commonwealth Trust Ii - Fidelity Large Cap Growth Enhanced Index Fund | Large-Cap Growth | 2,000 | New Holding | 2,000 | 100 % | $25,340 | $22,060 | $-3,280 | -12.94 % | $-3,280 | | | | | | News Article | History of Fidelity Commonwealth Trust Ii - Fidelity Large Cap Growth Enhanced Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-CSRS | Fidelity Commonwealth Trust Ii - Fidelity Small Cap Enhanced Index Fund | Small-Cap Core | 8,000 | Sold Some | -16,500 | -67.34 % | $101,360 | $88,240 | $-13,120 | -12.94 % | $27,060 | | | | | | News Article | History of Fidelity Commonwealth Trust Ii - Fidelity Small Cap Enhanced Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Fidelity Mt Vernon Street Trust - Fidelity Aggressive Growth Fund | Multi-Cap Growth | 645,083 | Sold Some | -9,785,893 | -93.81 % | $8,173,202 | $7,115,265 | $-1,057,936 | -12.94 % | $16,048,865 | | | | | | News Article | History of Fidelity Mt Vernon Street Trust - Fidelity Aggressive Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Fidelity Mt Vernon Street Trust - Fidelity Growth Company Fund | Multi-Cap Growth | 9,812,981 | New Holding | 9,812,981 | 100 % | $124,330,469 | $108,237,180 | $-16,093,289 | -12.94 % | $-16,093,289 | | | | | | News Article | History of Fidelity Mt Vernon Street Trust - Fidelity Growth Company Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Fidelity Securities Fund - Agressive Growth Fund | Global Small/Mid-Cap Growth | 11,066 | New Holding | 11,066 | 100 % | $140,206 | $122,058 | $-18,148 | -12.94 % | $-18,148 | | | | | | News Article | History of Fidelity Securities Fund - Agressive Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Sei Institutional Investments Trust - Siit Large Cap Fund | Large-Cap Core | | Sold All | -4,600 | -100 % | | | | -12.94 % | $7,544 | | | | | | News Article | History of Sei Institutional Investments Trust - Siit Large Cap Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-CSR | Vanguard World Fund - Vanguard Health Care Index Fund | Health/Biotech | 42,252 | New Holding | 42,252 | 100 % | $535,333 | $466,040 | $-69,293 | -12.94 % | $-69,293 | | | | | | News Article | History of Vanguard World Fund - Vanguard Health Care Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-29 | 2009-09-30 | 13F-HR | Dimensional Fund Advisors Inc | Institution | 684,619 | Sold Some | -28,849 | -4.04 % | $8,571,430 | $7,551,348 | $-1,020,082 | -11.90 % | $42,985 | | | | | | News Article | History of Dimensional Fund Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-29 | 2009-08-31 | N-Q | Usaa Mutual Funds Trust - Balanced Strategy Fund | Flexible Portfolio | 1,300 | New Holding | 1,300 | 100 % | $16,276 | $14,339 | $-1,937 | -11.90 % | $-1,937 | | | | | | News Article | History of Usaa Mutual Funds Trust - Balanced Strategy Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-29 | 2009-08-31 | N-Q | Usaa Mutual Funds Trust - Cornerstone Strategy Fund | Specialty & Misc | | Sold All | -5,200 | -100 % | | | | -11.90 % | $7,748 | | | | | | News Article | History of Usaa Mutual Funds Trust - Cornerstone Strategy Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-29 | 2009-08-31 | N-Q | Valic Co I - Small Cap Index Fund | Small-Cap Core | 75,401 | New Holding | 75,401 | 100 % | $944,021 | $831,673 | $-112,347 | -11.90 % | $-112,347 | | | | | | News Article | History of Valic Co I - Small Cap Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-29 | 2009-08-31 | N-Q | Valic Co I - Value Fund | Multi-Cap Value | | Sold All | -31,443 | -100 % | | | | -11.90 % | $46,850 | | | | | | News Article | History of Valic Co I - Value Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-28 | 2009-09-30 | 13F-HR | Davenport And Co Llc | Institution | 1,396,535 | Added More | 194,510 | 16.18 % | $17,191,346 | $15,403,781 | $-1,787,565 | -10.39 % | $-248,973 | | | | | | News Article | History of Davenport And Co Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-28 | 2009-09-30 | 13F-HR | Hirtle Callaghan Co Inc | Institution | 3,100 | No Change | 0 | 0 % | $38,161 | $34,193 | $-3,968 | -10.39 % | $0 | | | | | | News Article | History of Hirtle Callaghan Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-28 | 2009-09-30 | 13F-HR | Prentiss Smith And Co Inc | Institution | 200 | No Change | 0 | 0 % | $2,462 | $2,206 | $-256 | -10.39 % | $0 | | | | | | News Article | History of Prentiss Smith And Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-28 | 2009-09-30 | 13F-HR | Quotient Investors Llc | No Data | | Sold All | -13,200 | -100 % | | | | -10.39 % | $16,896 | | | | | | News Article | History of Quotient Investors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-28 | 2009-08-31 | N-Q | American Century Strategic Asset Allocations Inc - Newton Fund | Small-Cap Core | 19,037 | Added More | 2,388 | 14.34 % | $234,345 | $209,978 | $-24,367 | -10.39 % | $-3,057 | | | | | | News Article | History of American Century Strategic Asset Allocations Inc - Newton Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-27 | 2009-09-30 | 13F-HR | Essex Investment Management Co Llc | Institution | 2,113 | No Change | 0 | 0 % | $27,089 | $23,306 | $-3,782 | -13.96 % | $0 | | | | | | News Article | History of Essex Investment Management Co Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-26 | 2009-08-31 | N-Q | Claymore Exchange Traded Fund Trust - Claymoremorningstar Services Super Sector Index Etf | Specialty & Misc | 45 | No Change | 0 | 0 % | $592 | $496 | $-96 | -16.18 % | $0 | | | | | | News Article | History of Claymore Exchange Traded Fund Trust - Claymoremorningstar Services Super Sector Index Etf Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-26 | 2009-06-30 | 13F-HR/A | Ameriprise Financial Inc | Institution | 158,548 | Added More | 25,768 | 19.40 % | $2,086,492 | $1,748,784 | $-337,707 | -16.18 % | $-54,886 | | | | | | News Article | History of Ameriprise Financial Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-23 | 2009-09-30 | 13F-HR | Magee Thomson Investment Partners Llc | Institution | 6,657 | No Change | 0 | 0 % | $92,199 | $73,427 | $-18,773 | -20.36 % | $0 | | | | | | News Article | History of Magee Thomson Investment Partners Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-23 | 2009-09-30 | 13F-HR | Pinnacle Associates Ltd | Institution | 1,783,261 | Added More | 2,757 | 0.15 % | $24,698,165 | $19,669,369 | $-5,028,796 | -20.36 % | $-7,775 | | | | | | News Article | History of Pinnacle Associates Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-22 | 2009-09-30 | 13F-HR | Apex Capital Management | Institution | 73,212 | Added More | 31,661 | 76.19 % | $1,010,326 | $807,528 | $-202,797 | -20.07 % | $-87,701 | | | | | | News Article | History of Apex Capital Management Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-22 | 2009-09-30 | 13F-HR | Blackrock Group Ltd | Institution | 30,407 | No Change | 0 | 0 % | $419,617 | $335,389 | $-84,227 | -20.07 % | $0 | | | | | | News Article | History of Blackrock Group Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-22 | 2009-09-30 | 13F-HR | Blackrock Inc | No Data | | Sold All | -28,967 | -100 % | | | | -20.07 % | $80,239 | | | | | | News Article | History of Blackrock Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-22 | 2009-09-30 | 13F-HR | Blackrock Investment Management Llc | Institution | 264,909 | Added More | 51,136 | 23.92 % | $3,655,744 | $2,921,946 | $-733,798 | -20.07 % | $-141,647 | | | | | | News Article | History of Blackrock Investment Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-22 | 2009-09-30 | 13F-HR | Regions Financial Corp | Institution | 12,020 | New Holding | 12,020 | 100 % | $165,876 | $132,581 | $-33,295 | -20.07 % | $-33,295 | | | | | | News Article | History of Regions Financial Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-21 | 2009-09-30 | 13F-HR | Bank Of New York Mellon Corp | Institution | 474,241 | Sold Some | -268,517 | -36.15 % | $6,293,178 | $5,230,878 | $-1,062,300 | -16.88 % | $601,478 | | | | | | News Article | History of Bank Of New York Mellon Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-21 | 2009-09-30 | 13F-HR | Navellier And Associates Inc | Institution | 50,376 | Sold Some | -15,800 | -23.87 % | $668,490 | $555,647 | $-112,842 | -16.88 % | $35,392 | | | | | | News Article | History of Navellier And Associates Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-21 | 2009-09-30 | 13F-HR | State Board Of Administration Of Florida Retirement System | Institution | 136,637 | Added More | 35,701 | 35.36 % | $1,813,173 | $1,507,106 | $-306,067 | -16.88 % | $-79,970 | | | | | | News Article | History of State Board Of Administration Of Florida Retirement System Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-20 | 2009-09-30 | 13F-HR | Public Employees Retirement Association Of Colorado | Institution | 81,800 | No Change | 0 | 0 % | $1,117,388 | $902,254 | $-215,134 | -19.25 % | $0 | | | | | | News Article | History of Public Employees Retirement Association Of Colorado Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-19 | 2009-09-30 | 13F-HR | City National Bank | Institution | 52,614 | Added More | 2,457 | 4.89 % | $735,544 | $580,332 | $-155,211 | -21.10 % | $-7,248 | | | | | | News Article | History of City National Bank Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-19 | 2009-09-30 | 13F-HR | Strs Ohio | Institution | 33,500 | Sold Some | -15,600 | -31.77 % | $468,330 | $369,505 | $-98,825 | -21.10 % | $46,020 | | | | | | News Article | History of Strs Ohio Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-16 | 2009-09-30 | 13F-HR | Princeton Capital Management Inc | Institution | 55,200 | No Change | 0 | 0 % | $770,592 | $608,856 | $-161,736 | -20.98 % | $0 | | | | | | News Article | History of Princeton Capital Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-15 | 2009-09-30 | 13F-HR | Nordea Investment Management Ab | Institution | 373,800 | Added More | 74,070 | 24.71 % | $5,180,868 | $4,123,014 | $-1,057,854 | -20.41 % | $-209,618 | | | | | | News Article | History of Nordea Investment Management Ab Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-15 | 2009-09-30 | 13F-HR | Public Employees Retirement System Of Ohio | Institution | 145,113 | No Change | 0 | 0 % | $2,011,266 | $1,600,596 | $-410,670 | -20.41 % | $0 | | | | | | News Article | History of Public Employees Retirement System Of Ohio Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-15 | 2009-08-31 | N-Q | Allied Asset Advisors Funds - Allied Asset Advisor Funds | Specialty & Misc | 5,400 | New Holding | 5,400 | 100 % | $74,844 | $59,562 | $-15,282 | -20.41 % | $-15,282 | | | | | | News Article | History of Allied Asset Advisors Funds - Allied Asset Advisor Funds Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-14 | 2009-09-30 | 13F-HR | First Citizens Bank And Trust Co | Institution | | Sold All | -21,020 | -100 % | | | | -20.87 % | $61,168 | | | | | | News Article | History of First Citizens Bank And Trust Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-14 | 2009-09-30 | 13F-HR | Granahan Investment Management Inc | Institution | 1,529,449 | No Change | 0 | 0 % | $21,320,519 | $16,869,822 | $-4,450,697 | -20.87 % | $0 | | | | | | News Article | History of Granahan Investment Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-13 | 2009-09-30 | 13F-HR | Blb And B Advisors Llc | Institution | 63,880 | Added More | 30,440 | 91.02 % | $865,574 | $704,596 | $-160,978 | -18.59 % | $-76,709 | | | | | | News Article | History of Blb And B Advisors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-13 | 2009-09-30 | 13F-HR | Financial Architects Inc | Institution | | Sold All | -500 | -100 % | | | | -18.59 % | $1,260 | | | | | | News Article | History of Financial Architects Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-13 | 2009-09-30 | 13F-HR | Gofen And Glossberg Llc | Institution | 21,350 | No Change | 0 | 0 % | $289,293 | $235,491 | $-53,802 | -18.59 % | $0 | | | | | | News Article | History of Gofen And Glossberg Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-09 | 2009-07-31 | N-CSR | Advisors Inner Circle Fund Ii - Growth Fund | Small-Cap Growth | 102,790 | Added More | 57,670 | 127.81 % | $1,441,116 | $1,133,774 | $-307,342 | -21.32 % | $-172,433 | | | | | | News Article | History of Advisors Inner Circle Fund Ii - Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-08 | 2009-09-30 | 13F-HR | Rhumbline Advisers | Institution | 128,189 | Sold Some | -3,100 | -2.36 % | $1,771,572 | $1,413,925 | $-357,647 | -20.18 % | $8,649 | | | | | | News Article | History of Rhumbline Advisers Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-07 | 2009-07-31 | N-CSR | Fidelity Advisor Series Vii - Fidelity Advisor Biotechnology Fund | Health/Biotech | 75,800 | Added More | 36,200 | 91.41 % | $1,052,104 | $836,074 | $-216,030 | -20.53 % | $-103,170 | | | | | | News Article | History of Fidelity Advisor Series Vii - Fidelity Advisor Biotechnology Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-07 | 2009-07-31 | N-CSR | Profunds - Bull Profund | Large-Cap Core | 3,392 | Added More | 1,680 | 98.13 % | $47,081 | $37,414 | $-9,667 | -20.53 % | $-4,788 | | | | | | News Article | History of Profunds - Bull Profund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-07 | 2009-07-31 | N-CSR | Profunds - Health Care Ultrasector Profund | Health/Biotech | 438 | Added More | 268 | 157.64 % | $6,079 | $4,831 | $-1,248 | -20.53 % | $-764 | | | | | | News Article | History of Profunds - Health Care Ultrasector Profund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-07 | 2009-07-31 | N-CSR | Profunds - Technology Ultrasector Profund | Science & Tech | 4,624 | New Holding | 4,624 | 100 % | $64,181 | $51,003 | $-13,178 | -20.53 % | $-13,178 | | | | | | News Article | History of Profunds - Technology Ultrasector Profund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-06 | 2009-09-30 | 13F-HR | Franklin Street Advisors Inc | Institution | 69,100 | Added More | 8,900 | 14.78 % | $978,456 | $762,173 | $-216,283 | -22.10 % | $-27,857 | | | | | | News Article | History of Franklin Street Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-05 | 2009-09-30 | 13F-HR | Johnston Asset Management Corp | Institution | 719,076 | Sold Some | -81,200 | -10.14 % | $9,894,486 | $7,931,408 | $-1,963,077 | -19.84 % | $221,676 | | | | | | News Article | History of Johnston Asset Management Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-02 | 2009-07-31 | N-CSR | Old Mutual Advisor Funds - Old Mutual Copper Rock Emerging Growth Fund | Small-Cap Growth | | Sold All | -18,967 | -100 % | | | | -20.53 % | $54,056 | | | | | | News Article | History of Old Mutual Advisor Funds - Old Mutual Copper Rock Emerging Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-02 | 2009-07-31 | N-CSR | Usaa Mutual Funds Trust - Small Cap Stock Fund | Small-Cap Core | 115,200 | No Change | 0 | 0 % | $1,598,976 | $1,270,656 | $-328,320 | -20.53 % | $0 | | | | | | News Article | History of Usaa Mutual Funds Trust - Small Cap Stock Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | American Century Mutual Funds Inc - Balanced Fund | Mixed-Asset Target Allocation Growth | 11,304 | Added More | 234 | 2.11 % | $167,638 | $124,683 | $-42,955 | -25.62 % | $-889 | | | | | | News Article | History of American Century Mutual Funds Inc - Balanced Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | American Century Mutual Funds Inc - New Opportunities Fund | Small-Cap Growth | 29,946 | Sold Some | -2,258 | -7.01 % | $444,099 | $330,304 | $-113,795 | -25.62 % | $8,580 | | | | | | News Article | History of American Century Mutual Funds Inc - New Opportunities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | American Century Mutual Funds Inc - New Opportunities Ii | Small-Cap Growth | 103,415 | Sold Some | -16,819 | -13.98 % | $1,533,644 | $1,140,667 | $-392,977 | -25.62 % | $63,912 | | | | | | News Article | History of American Century Mutual Funds Inc - New Opportunities Ii Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dfa Investment Dimensions Group Inc - International Core Equity Portfolio | International Small-Mid-Cap Value | 58,097 | New Holding | 58,097 | 100 % | $861,579 | $640,810 | $-220,769 | -25.62 % | $-220,769 | | | | | | News Article | History of Dfa Investment Dimensions Group Inc - International Core Equity Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dfa Investment Dimensions Group Inc - International Vector Equity Portfolio | No Data | 10,070 | New Holding | 10,070 | 100 % | $149,338 | $111,072 | $-38,266 | -25.62 % | $-38,266 | | | | | | News Article | History of Dfa Investment Dimensions Group Inc - International Vector Equity Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dfa Investment Dimensions Group Inc - Us Sustainability Core 1 Portfolio | No Data | 900 | New Holding | 900 | 100 % | $13,347 | $9,927 | $-3,420 | -25.62 % | $-3,420 | | | | | | News Article | History of Dfa Investment Dimensions Group Inc - Us Sustainability Core 1 Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dws Balanced Fund - Dws Balanced Fund | Flexible Portfolio | | Sold All | -11,700 | -100 % | | | | -25.62 % | $44,460 | | | | | | News Article | History of Dws Balanced Fund - Dws Balanced Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dws Blue Chip Fund - Dws Blue Chip Fund | Multi-Cap Core | | Sold All | -5,500 | -100 % | | | | -25.62 % | $20,900 | | | | | | News Article | History of Dws Blue Chip Fund - Dws Blue Chip Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dws Equity Trust - Dws Disciplined Longshort Growth Fund | Multi-Cap Growth | 2,000 | New Holding | 2,000 | 100 % | $29,660 | $22,060 | $-7,600 | -25.62 % | $-7,600 | | | | | | News Article | History of Dws Equity Trust - Dws Disciplined Longshort Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | First American Investment Funds Inc - Small Cap Growth Opportunities Fund | Small-Cap Growth | 85,962 | New Holding | 85,962 | 100 % | $1,274,816 | $948,161 | $-326,656 | -25.62 % | $-326,656 | | | | | | News Article | History of First American Investment Funds Inc - Small Cap Growth Opportunities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Ishares Trust - Ishares Morningstar Small Growth Index Fund | Small-Cap Growth | 30,768 | Added More | 6,042 | 24.43 % | $456,289 | $339,371 | $-116,918 | -25.62 % | $-22,960 | | | | | | News Article | History of Ishares Trust - Ishares Morningstar Small Growth Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Jnl Investors Series Trust - Jackson Perspective Index 5 Fund | Specialty & Misc | 1,101 | No Change | 0 | 0 % | $16,328 | $12,144 | $-4,184 | -25.62 % | $0 | | | | | | News Article | History of Jnl Investors Series Trust - Jackson Perspective Index 5 Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Russell Investment Co - International Fund | International Multi-Cap Core | | Sold All | -41,272 | -100 % | | | | -25.62 % | $156,834 | | | | | | News Article | History of Russell Investment Co - International Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Vanguard Explorer Fund - Vanguard Explorer Fund | Small-Cap Growth | 1,691,749 | Sold Some | -125,000 | -6.88 % | $25,088,638 | $18,659,991 | $-6,428,646 | -25.62 % | $475,000 | | | | | | News Article | History of Vanguard Explorer Fund - Vanguard Explorer Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Dryden Small Cap Core Equity Fund Inc - Dryden Small Cap Core Equity Fund Inc | Small-Cap Core | 7,200 | New Holding | 7,200 | 100 % | $108,360 | $79,416 | $-28,944 | -26.71 % | $-28,944 | | | | | | News Article | History of Dryden Small Cap Core Equity Fund Inc - Dryden Small Cap Core Equity Fund Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Dryden Tax Managed Funds - Dryden Large Cap Core Equity Fund | Large-Cap Core | 17,700 | New Holding | 17,700 | 100 % | $266,385 | $195,231 | $-71,154 | -26.71 % | $-71,154 | | | | | | News Article | History of Dryden Tax Managed Funds - Dryden Large Cap Core Equity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Fbr Funds - Fbr Pegasus Fund | Multi-Cap Value | 1,190 | New Holding | 1,190 | 100 % | $17,910 | $13,126 | $-4,784 | -26.71 % | $-4,784 | | | | | | News Article | History of Fbr Funds - Fbr Pegasus Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Massmutual Premier Funds - Massmutual Premier Main Street Small Cap Fund | Small-Cap Core | 2,460 | Sold Some | -280 | -10.21 % | $37,023 | $27,134 | $-9,889 | -26.71 % | $1,126 | | | | | | News Article | History of Massmutual Premier Funds - Massmutual Premier Main Street Small Cap Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Massmutual Premier Funds - Massmutual Premier Small Company Opportunities Fund | Small-Cap Core | 5,100 | No Change | 0 | 0 % | $76,755 | $56,253 | $-20,502 | -26.71 % | $0 | | | | | | News Article | History of Massmutual Premier Funds - Massmutual Premier Small Company Opportunities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Old Westbury Funds Inc - International Fund | International Multi-Cap Core | 10,035 | No Change | 0 | 0 % | $151,027 | $110,686 | $-40,341 | -26.71 % | $0 | | | | | | News Article | History of Old Westbury Funds Inc - International Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Powershares Exchange Traded Fund Trust - Powershares Dynamic Market Portfolio | Specialty & Misc | 268,102 | New Holding | 268,102 | 100 % | $4,034,935 | $2,957,165 | $-1,077,770 | -26.71 % | $-1,077,770 | | | | | | News Article | History of Powershares Exchange Traded Fund Trust - Powershares Dynamic Market Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Powershares Exchange-Traded Fund Trust Ii - Powershares Global Biotech Portfolio | No Data | 2,211 | Added More | 172 | 8.43 % | $33,276 | $24,387 | $-8,888 | -26.71 % | $-691 | | | | | | News Article | History of Powershares Exchange-Traded Fund Trust Ii - Powershares Global Biotech Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Schwab Capital Trust - Schwab Health Care Fund | Health/Biotech | 50,000 | New Holding | 50,000 | 100 % | $752,500 | $551,500 | $-201,000 | -26.71 % | $-201,000 | | | | | | News Article | History of Schwab Capital Trust - Schwab Health Care Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Tocqueville Trust - The Tocqueville Fund | Specialty & Misc | 250,000 | New Holding | 250,000 | 100 % | $3,762,500 | $2,757,500 | $-1,005,000 | -26.71 % | $-1,005,000 | | | | | | News Article | History of Tocqueville Trust - The Tocqueville Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-06-30 | 13F-HR/A | Bridgewater Investment Management Llc | Institution | | Sold All | -492 | -100 % | | | | -26.71 % | $1,978 | | | | | | News Article | History of Bridgewater Investment Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-25 | 2009-07-31 | N-Q | Direxion Shares Etf Trust - Direxion Daily Small Cap Bull 3x Shares | No Data | 24,523 | Sold Some | -3,518 | -12.54 % | $357,055 | $270,489 | $-86,566 | -24.24 % | $12,419 | | | | | | News Article | History of Direxion Shares Etf Trust - Direxion Daily Small Cap Bull 3x Shares Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-25 | 2009-07-31 | N-Q | Mtb Group Of Funds - Mtb Multi Cap Growth Fund | Multi-Cap Core | | Sold All | -1,000 | -100 % | | | | -24.24 % | $3,530 | | | | | | News Article | History of Mtb Group Of Funds - Mtb Multi Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-25 | 2009-07-31 | N-Q | Mtb Group Of Funds - Mtb Small Cap Growth Fund | Small-Cap Growth | | Sold All | -65,324 | -100 % | | | | -24.24 % | $230,594 | | | | | | News Article | History of Mtb Group Of Funds - Mtb Small Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-25 | 2009-06-30 | 13F-HR/A | Kbc Group Nv | Institution | 24,380 | Sold Some | -6,727 | -21.62 % | $354,973 | $268,911 | $-86,061 | -24.24 % | $23,746 | | | | | | News Article | History of Kbc Group Nv Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-17 | 2009-07-31 | N-Q | Rydex Etf Trust - Rydex Inverse Russell 2000 Etf | Specialty & Misc | 2,000 | New Holding | 2,000 | 100 % | $30,460 | $22,060 | $-8,400 | -27.57 % | $-8,400 | | | | | | News Article | History of Rydex Etf Trust - Rydex Inverse Russell 2000 Etf Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-15 | 2009-06-30 | N-CSRS/A | Wilshire Mutual Funds Inc - Wilshire Small Company Growth Portfolio | Small-Cap Growth | | Sold All | -129 | -100 % | | | | -28.93 % | $579 | | | | | | News Article | History of Wilshire Mutual Funds Inc - Wilshire Small Company Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-11 | 2009-06-30 | 13F-HR/A | Barclays Global Investors Uk Holdings Ltd | Institution | 5,497,444 | Added More | 572,673 | 11.62 % | $85,155,408 | $60,636,807 | $-24,518,600 | -28.79 % | $-2,554,122 | | | | | | News Article | History of Barclays Global Investors Uk Holdings Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-11 | 2009-06-30 | 13F-HR/A | Barclays Global Investors Uk Holdings Ltd | Institution | 5,254,572 | Added More | 329,801 | 6.69 % | $81,393,320 | $57,957,929 | $-23,435,391 | -28.79 % | $-1,470,912 | | | | | | News Article | History of Barclays Global Investors Uk Holdings Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-08 | 2009-06-30 | N-CSRS | Allianz Variable Insurance Products Trust - Azl Lmp Small Cap Growth Fund | Small-Cap Growth | | Sold All | -15,730 | -100 % | | | | -28.51 % | $69,212 | | | | | | News Article | History of Allianz Variable Insurance Products Trust - Azl Lmp Small Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-08 | 2009-06-30 | N-CSRS | Allianz Variable Insurance Products Trust - Azl Occ Opportunity Fund | Specialty & Misc | 71,100 | Added More | 10,975 | 18.25 % | $1,097,073 | $784,233 | $-312,840 | -28.51 % | $-48,290 | | | | | | News Article | History of Allianz Variable Insurance Products Trust - Azl Occ Opportunity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-08 | 2009-06-30 | N-CSRS | Rydex Series Funds - Banking Fund | Financial Services | 2,491 | Sold Some | -414 | -14.25 % | $38,436 | $27,476 | $-10,960 | -28.51 % | $1,822 | | | | | | News Article | History of Rydex Series Funds - Banking Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-08 | 2009-06-30 | N-CSRS | Rydex Variable Trust - Biotechnology Fund | Health/Biotech | 19,008 | Sold Some | -14,524 | -43.31 % | $293,293 | $209,658 | $-83,635 | -28.51 % | $63,906 | | | | | | News Article | History of Rydex Variable Trust - Biotechnology Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-08 | 2009-06-30 | N-CSRS | Timothy Plan - Timothy Aggressive Growth Fund | Multi-Cap Growth | | Sold All | -4,500 | -100 % | | | | -28.51 % | $19,800 | | | | | | News Article | History of Timothy Plan - Timothy Aggressive Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Advanced Series Trust - Ast Federated Aggressive Growth Portfolio | Multi-Cap Growth | 146,500 | Added More | 23,100 | 18.71 % | $2,267,820 | $1,615,895 | $-651,925 | -28.74 % | $-102,795 | | | | | | News Article | History of Advanced Series Trust - Ast Federated Aggressive Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Advanced Series Trust - Ast Pimco Total Return Bond Portfolio | Specialty & Misc | | Sold All | -27,300 | -100 % | | | | -28.74 % | $121,485 | | | | | | News Article | History of Advanced Series Trust - Ast Pimco Total Return Bond Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Advanced Series Trust - Ast Western Asset Core Plus Bond Portfolio | No Data | | Sold All | -7,700 | -100 % | | | | -28.74 % | $34,265 | | | | | | News Article | History of Advanced Series Trust - Ast Western Asset Core Plus Bond Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Axa Premier Vip Trust - Multimanager Small Cap Growth Portfolio | Small-Cap Growth | 51,500 | Sold Some | -16,800 | -24.59 % | $797,220 | $568,045 | $-229,175 | -28.74 % | $74,760 | | | | | | News Article | History of Axa Premier Vip Trust - Multimanager Small Cap Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Eq Advisors Trust - Eqalliancebernstein Small Cap Growth Portfolio | Small-Cap Growth | 59,600 | No Change | 0 | 0 % | $922,608 | $657,388 | $-265,220 | -28.74 % | $0 | | | | | | News Article | History of Eq Advisors Trust - Eqalliancebernstein Small Cap Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Eq Advisors Trust - Eqalliancebernstein Value Portfolio | Multi-Cap Value | 16,610 | New Holding | 16,610 | 100 % | $257,123 | $183,208 | $-73,915 | -28.74 % | $-73,915 | | | | | | News Article | History of Eq Advisors Trust - Eqalliancebernstein Value Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Eq Advisors Trust - Eqbond Index Portfolio | Specialty & Misc | 311,880 | Added More | 193,480 | 163.41 % | $4,827,902 | $3,440,036 | $-1,387,866 | -28.74 % | $-860,986 | | | | | | News Article | History of Eq Advisors Trust - Eqbond Index Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSR | Frontegra Funds Inc - Frontegra Ironbridge Smid Fund | Mid-Cap Core | | Sold All | -134,217 | -100 % | | | | -28.74 % | $597,266 | | | | | | News Article | History of Frontegra Funds Inc - Frontegra Ironbridge Smid Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSR | Jpmorgan Trust I - Jpmorgan Small Cap Core Fund | Small-Cap Core | 49 | New Holding | 49 | 100 % | $759 | $540 | $-218 | -28.74 % | $-218 | | | | | | News Article | History of Jpmorgan Trust I - Jpmorgan Small Cap Core Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSR | Jpmorgan Trust Ii - Jpmorgan Core Bond Fund | Multi-Cap Core | 49 | New Holding | 49 | 100 % | $759 | $540 | $-218 | -28.74 % | $-218 | | | | | | News Article | History of Jpmorgan Trust Ii - Jpmorgan Core Bond Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Profunds - Bull Profund | Large-Cap Core | 1,712 | Sold Some | -2,800 | -62.05 % | $26,502 | $18,883 | $-7,618 | -28.74 % | $12,460 | | | | | | News Article | History of Profunds - Bull Profund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Profunds - Profund Vp Biotechnology | Health/Biotech | 5,508 | New Holding | 5,508 | 100 % | $85,264 | $60,753 | $-24,511 | -28.74 % | $-24,511 | | | | | | News Article | History of Profunds - Profund Vp Biotechnology Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Profunds - Profund Vp Health Care | Health/Biotech | 3,024 | Added More | 1,534 | 102.95 % | $46,812 | $33,355 | $-13,457 | -28.74 % | $-6,826 | | | | | | News Article | History of Profunds - Profund Vp Health Care Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Sun Capital Advisers Trust - Sc Aim Small Cap Growth Fund | No Data | 3,966 | Added More | 1,866 | 88.85 % | $61,394 | $43,745 | $-17,649 | -28.74 % | $-8,304 | | | | | | News Article | History of Sun Capital Advisers Trust - Sc Aim Small Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Sun Capital Advisers Trust - Sc Oppenheimer Main Street Small Cap Fund | Small-Cap Core | 4,780 | Added More | 3,580 | 298.33 % | $73,994 | $52,723 | $-21,271 | -28.74 % | $-15,931 | | | | | | News Article | History of Sun Capital Advisers Trust - Sc Oppenheimer Main Street Small Cap Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Vanguard Institutional Index Funds - Vanguard Institutional Index Fund | Specialty & Misc | 84,307 | New Holding | 84,307 | 100 % | $1,305,072 | $929,906 | $-375,166 | -28.74 % | $-375,166 | | | | | | News Article | History of Vanguard Institutional Index Funds - Vanguard Institutional Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Vanguard Variable Insurance Funds - Small Company Growth Portfolio | Small-Cap Growth | 264,750 | New Holding | 264,750 | 100 % | $4,098,330 | $2,920,193 | $-1,178,138 | -28.74 % | $-1,178,138 | | | | | | News Article | History of Vanguard Variable Insurance Funds - Small Company Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSR | American Century Quantitative Equity Funds Inc - Utilities Fund | Utility | | Sold All | -35,321 | -100 % | | | | - % | | | | | | | News Article | History of American Century Quantitative Equity Funds Inc - Utilities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSRS | Jnl Variable Fund Llc - Jnlmcm Healthcare Sector Fund | Health/Biotech | 9 | No Change | 0 | 0 % | | $99 | | - % | | | | | | | News Article | History of Jnl Variable Fund Llc - Jnlmcm Healthcare Sector Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSRS | Mml Series Investment Fund Ii - Mml Small Cap Equity Fund | Small-Cap Core | 3,930 | Added More | 3,160 | 410.38 % | | $43,348 | | - % | | | | | | | News Article | History of Mml Series Investment Fund Ii - Mml Small Cap Equity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSRS | Ohio National Fund Inc - Bryton Growth Portfolio | Multi-Cap Growth | | Sold All | -45,000 | -100 % | | | | - % | | | | | | | News Article | History of Ohio National Fund Inc - Bryton Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSRS | Pacific Select Fund - Pd Small-Cap Growth Index Portfolio | No Data | 3,218 | No Compare | | | | $35,495 | | - % | | | | | | | News Article | History of Pacific Select Fund - Pd Small-Cap Growth Index Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSR | Streettracks Series Trust - Spdr Dividend Etf | Specialty & Misc | | Sold All | -1,392,533 | -100 % | | | | - % | | | | | | | News Article | History of Streettracks Series Trust - Spdr Dividend Etf Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-02 | 2009-06-30 | N-CSRS | Met Investors Series Trust - Metaim Small Cap Growth Portfolio | Small-Cap Growth | 220,683 | Added More | 44,283 | 25.10 % | $3,427,207 | $2,434,133 | $-993,074 | -28.97 % | $-199,274 | | | | | | News Article | History of Met Investors Series Trust - Metaim Small Cap Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-01 | 2009-06-30 | 13F-HR/A | Amvescap Plc | Institution | 961,547 | Sold Some | -378,257 | -28.23 % | $15,086,672 | $10,605,863 | $-4,480,809 | -29.70 % | $1,762,678 | | | | | | News Article | History of Amvescap Plc Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-01 | 2009-06-30 | 13F-HR/A | Fidelity International Ltd | Institution | 3,580 | New Holding | 3,580 | 100 % | $56,170 | $39,487 | $-16,683 | -29.70 % | $-16,683 | | | | | | News Article | History of Fidelity International Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-01 | 2009-06-30 | 13F-HR/A | Fmr Corp | Institution | 14,715,972 | Added More | 439,215 | 3.07 % | $230,893,601 | $162,317,171 | $-68,576,430 | -29.70 % | $-2,046,742 | | | | | | News Article | History of Fmr Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-01 | 2009-06-30 | N-Q/A | Rydex Series Funds - Biotechnology Fund | Health/Biotech | 116,772 | Added More | 11,009 | 10.40 % | $1,832,153 | $1,287,995 | $-544,158 | -29.70 % | $-51,302 | | | | | | News Article | History of Rydex Series Funds - Biotechnology Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-31 | 2009-06-30 | N-CSRS | Mutual Of America Investment Corp - Bond Fund | Specialty & Misc | 45,913 | Added More | 393 | 0.86 % | $741,036 | $506,420 | $-234,615 | -31.66 % | $-2,008 | | | | | | News Article | History of Mutual Of America Investment Corp - Bond Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-31 | 2009-06-30 | N-Q | Sei Institutional Managed Trust - Large Cap Diversified Alpha Fund | Large-Cap Core | 9,900 | New Holding | 9,900 | 100 % | $159,786 | $109,197 | $-50,589 | -31.66 % | $-50,589 | | | | | | News Article | History of Sei Institutional Managed Trust - Large Cap Diversified Alpha Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-31 | 2009-06-30 | N-CSRS | Tiaa Cref Life Fund - Stock Index Fund | Specialty & Misc | 1,170 | No Change | 0 | 0 % | $18,884 | $12,905 | $-5,979 | -31.66 % | $0 | | | | | | News Article | History of Tiaa Cref Life Fund - Stock Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-CSR | Allianz Funds - Occ Value | Large-Cap Value | 114,650 | Added More | 15,975 | 16.18 % | $1,851,598 | $1,264,590 | $-587,008 | -31.70 % | $-81,792 | | | | | | News Article | History of Allianz Funds - Occ Value Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Calvert Social Investment Fund - Equity Portfolio | Multi-Cap Core | 1,800 | New Holding | 1,800 | 100 % | $29,070 | $19,854 | $-9,216 | -31.70 % | $-9,216 | | | | | | News Article | History of Calvert Social Investment Fund - Equity Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-CSRS | Columbia Funds Variable Insurance Trust - Columbia Asset Allocation Fund Variable Series | Specialty & Misc | 790 | New Holding | 790 | 100 % | $12,759 | $8,714 | $-4,045 | -31.70 % | $-4,045 | | | | | | News Article | History of Columbia Funds Variable Insurance Trust - Columbia Asset Allocation Fund Variable Series Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-CSRS | Columbia Funds Variable Insurance Trust - Columbia Small Company Growth Fund Variable Series | Small-Cap Growth | 13,900 | New Holding | 13,900 | 100 % | $224,485 | $153,317 | $-71,168 | -31.70 % | $-71,168 | | | | | | News Article | History of Columbia Funds Variable Insurance Trust - Columbia Small Company Growth Fund Variable Series Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-CSRS | Dws Variable Series Ii - Dws Balanced Vip | Flexible Portfolio | | Sold All | -11,000 | -100 % | | | | -31.70 % | $56,320 | | | | | | News Article | History of Dws Variable Series Ii - Dws Balanced Vip Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-CSRS | Dws Variable Series Ii - Dws Blue Chip Vip | Specialty & Misc | | Sold All | -2,200 | -100 % | | | | -31.70 % | $11,264 | | | | | | News Article | History of Dws Variable Series Ii - Dws Blue Chip Vip Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ishares Trust - Ishares Nasdaq Biotechnology Index Fund | Health/Biotech | 835,965 | Sold Some | -44,222 | -5.02 % | $13,500,835 | $9,220,694 | $-4,280,141 | -31.70 % | $226,417 | | | | | | News Article | History of Ishares Trust - Ishares Nasdaq Biotechnology Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ishares Trust - Ishares Russell 2000 Growth Index Fund | Multi-Cap Growth | 659,658 | Added More | 46,218 | 7.53 % | $10,653,477 | $7,276,028 | $-3,377,449 | -31.70 % | $-236,636 | | | | | | News Article | History of Ishares Trust - Ishares Russell 2000 Growth Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ishares Trust - Ishares Russell 2000 Index Fund | Specialty & Misc | 1,123,453 | Added More | 6,401 | 0.57 % | $18,143,766 | $12,391,687 | $-5,752,079 | -31.70 % | $-32,773 | | | | | | News Article | History of Ishares Trust - Ishares Russell 2000 Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ishares Trust - Ishares Russell 3000 Growth Index Fund | Multi-Cap Growth | 5,887 | Sold Some | -319 | -5.14 % | $95,075 | $64,934 | $-30,141 | -31.70 % | $1,633 | | | | | | News Article | History of Ishares Trust - Ishares Russell 3000 Growth Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ishares Trust - Ishares Russell 3000 Index Fund | Specialty & Misc | 26,394 | Added More | 1,560 | 6.28 % | $426,263 | $291,126 | $-135,137 | -31.70 % | $-7,987 | | | | | | News Article | History of Ishares Trust - Ishares Russell 3000 Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Loomis Sayles Funds I - Loomis Sayles Bond Fund | Specialty & Misc | | Sold All | -49,143 | -100 % | | | | -31.70 % | $251,612 | | | | | | News Article | History of Loomis Sayles Funds I - Loomis Sayles Bond Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Loomis Sayles Funds Ii - Loomis Sayles Small Cap Growth Fund | Small-Cap Growth | 48,621 | Sold Some | -522 | -1.06 % | $785,229 | $536,290 | $-248,940 | -31.70 % | $2,673 | | | | | | News Article | History of Loomis Sayles Funds Ii - Loomis Sayles Small Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Riversource Strategic Allocation Series Inc - Riversource Strategic Allocation Fund | Flexible Portfolio | 25,688 | New Holding | 25,688 | 100 % | $414,861 | $283,339 | $-131,523 | -31.70 % | $-131,523 | | | | | | News Article | History of Riversource Strategic Allocation Series Inc - Riversource Strategic Allocation Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Riversource Strategy Series Inc - Riversource Small Cap Growth Fund | Small-Cap Growth | 12,100 | New Holding | 12,100 | 100 % | $195,415 | $133,463 | $-61,952 | -31.70 % | $-61,952 | | | | | | News Article | History of Riversource Strategy Series Inc - Riversource Small Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Seasons Series Trust - Stock Portfolio | Multi-Cap Core | 2,033 | New Holding | 2,033 | 100 % | $32,833 | $22,424 | $-10,409 | -31.70 % | $-10,409 | | | | | | News Article | History of Seasons Series Trust - Stock Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Sti Classic Funds - Small Cap Growth Stock Fund | Small-Cap Growth | 137,990 | Sold Some | -5,280 | -3.68 % | $2,228,539 | $1,522,030 | $-706,509 | -31.70 % | $27,034 | | | | | | News Article | History of Sti Classic Funds - Small Cap Growth Stock Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | 13F-HR/A | Wells Fargo And Co | Institution | 505,056 | Sold Some | -18,807 | -3.59 % | $8,156,654 | $5,570,768 | $-2,585,887 | -31.70 % | $96,292 | | | | | | News Article | History of Wells Fargo And Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2008-06-30 | N-Q | Vanguard Horizon Funds - Vanguard Strategic Equity Fund | Specialty & Misc | 1,525,802 | New Holding | 1,525,802 | 100 % | $24,641,702 | $16,829,596 | $-7,812,106 | -31.70 % | $-7,812,106 | | | | | | News Article | History of Vanguard Horizon Funds - Vanguard Strategic Equity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2008-06-30 | N-Q | Vanguard Horizon Funds - Vanguard Strategic Small-Cap Equity Fund | Small-Cap Core | 52,000 | New Holding | 52,000 | 100 % | $839,800 | $573,560 | $-266,240 | -31.70 % | $-266,240 | | | | | | News Article | History of Vanguard Horizon Funds - Vanguard Strategic Small-Cap Equity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Dws Advisor Funds - Dws Lifecycle Long Range Fund | Mixed-Asset Target Allocation Moderate | 3,800 | New Holding | 3,800 | 100 % | $62,586 | $41,914 | $-20,672 | -33.02 % | $-20,672 | | | | | | News Article | History of Dws Advisor Funds - Dws Lifecycle Long Range Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Ivy Funds Inc - Ivy Science And Technology Fund | Science & Tech | 483 | Added More | 182 | 60.46 % | $7,955 | $5,327 | $-2,628 | -33.02 % | $-990 | | | | | | News Article | History of Ivy Funds Inc - Ivy Science And Technology Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Leuthold Funds Inc - Leuthold Core Investment Fund | Flexible Portfolio | 273,520 | Added More | 72,650 | 36.16 % | $4,504,874 | $3,016,926 | $-1,487,949 | -33.02 % | $-395,216 | | | | | | News Article | History of Leuthold Funds Inc - Leuthold Core Investment Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Leuthold Funds Inc - Leuthold Select Industries Fund | Specialty Dvsfd Eq | 14,808 | Added More | 3,095 | 26.42 % | $243,888 | $163,332 | $-80,556 | -33.02 % | $-16,837 | | | | | | News Article | History of Leuthold Funds Inc - Leuthold Select Industries Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Old Mutual Advisor Funds Ii - Old Mutual Strategic Small Company Fund | Small-Cap Core | | Sold All | -8,560 | -100 % | | | | -33.02 % | $46,566 | | | | | | News Article | History of Old Mutual Advisor Funds Ii - Old Mutual Strategic Small Company Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Tiaa Cref Institutional Mutual Funds - Equity Index Fund | Specialty & Misc | 62,921 | Added More | 40,598 | 181.86 % | $1,036,309 | $694,019 | $-342,290 | -33.02 % | $-220,853 | | | | | | News Article | History of Tiaa Cref Institutional Mutual Funds - Equity Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Tiaa Cref Institutional Mutual Funds - Growth Equity Fund | Multi-Cap Growth | | Sold All | -32,113 | -100 % | | | | -33.02 % | $174,695 | | | | | | News Article | History of Tiaa Cref Institutional Mutual Funds - Growth Equity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-CSRS | Vanguard Index Funds - Vanguard Extended Market Index Fund | Mid-Cap Core | 596,740 | New Holding | 596,740 | 100 % | $9,828,308 | $6,582,042 | $-3,246,266 | -33.02 % | $-3,246,266 | | | | | | News Article | History of Vanguard Index Funds - Vanguard Extended Market Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-CSRS | Vanguard Index Funds - Vanguard Growth Index Fund | Large-Cap Growth | 715,561 | New Holding | 715,561 | 100 % | $11,785,290 | $7,892,638 | $-3,892,652 | -33.02 % | $-3,892,652 | | | | | | News Article | History of Vanguard Index Funds - Vanguard Growth Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-CSRS | Vanguard Index Funds - Vanguard Total Stock Market Index Fund | Multi-Cap Core | 894,367 | New Holding | 894,367 | 100 % | $14,730,224 | $9,864,868 | $-4,865,356 | -33.02 % | $-4,865,356 | | | | | | News Article | History of Vanguard Index Funds - Vanguard Total Stock Market Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2008-06-30 | N-CSRS | Vanguard Balanced Index Funds - Vanguard Balanced Index Fund | Mixed-Asset Target Allocation Growth | 36,225 | Added More | 2,725 | 8.13 % | $596,626 | $399,562 | $-197,064 | -33.02 % | $-14,824 | | | | | | News Article | History of Vanguard Balanced Index Funds - Vanguard Balanced Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2008-06-30 | N-CSRS | Vanguard Balanced Index Funds - Vanguard Balanced Index Fund | Mixed-Asset Target Allocation Growth | 43,625 | Added More | 10,125 | 30.22 % | $718,504 | $481,184 | $-237,320 | -33.02 % | $-55,080 | | | | | | News Article | History of Vanguard Balanced Index Funds - Vanguard Balanced Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-26 | 2009-06-30 | N-Q | Vanguard Quantitative Funds - Vanguard Structured Broad Market | Multi-Cap Core | | Sold All | -20,030 | -100 % | | | | -32.20 % | $104,957 | | | | | | News Article | History of Vanguard Quantitative Funds - Vanguard Structured Broad Market Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-25 | 2009-06-30 | 13F-HR/A | Jefferies Group Inc | Institution | | Sold All | -13,700 | -100 % | | | | -31.06 % | $68,089 | | | | | | News Article | History of Jefferies Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-25 | 2009-06-30 | N-CSRS | Maxim Series Fund Inc - Maxim Small-Cap Growth Portfolio | No Data | 30,600 | New Holding | 30,600 | 100 % | $489,600 | $337,518 | $-152,082 | -31.06 % | $-152,082 | | | | | | News Article | History of Maxim Series Fund Inc - Maxim Small-Cap Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-25 | 2009-06-30 | N-Q | Oppenheimer Global Opportunities Fund - Oppenheimer Global Opportunities Fund | Global Flex Port | | Sold All | -3,000,000 | -100 % | | | | -31.06 % | $14,910,000 | | | | | | News Article | History of Oppenheimer Global Opportunities Fund - Oppenheimer Global Opportunities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-24 | 2009-06-30 | 13F-HR | Advent Capital Management | Institution | 50,000 | Sold Some | -10,000 | -16.66 % | $800,000 | $551,500 | $-248,500 | -31.06 % | $49,700 | | | | | | News Article | History of Advent Capital Management Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-24 | 2009-06-30 | N-CSRS | Genworth Variable Insurance Trust - Genworth Legg Mason Partners Aggressive Growth Fund | No Data | 14,620 | No Compare | | | $233,920 | $161,259 | $-72,661 | -31.06 % | | | | | | | News Article | History of Genworth Variable Insurance Trust - Genworth Legg Mason Partners Aggressive Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-24 | 2009-06-30 | N-CSRS | Oppenheimer Variable Account Funds - Oppenheimer Main Street Fundva | Specialty & Misc | 23,600 | New Holding | 23,600 | 100 % | $377,600 | $260,308 | $-117,292 | -31.06 % | $-117,292 | | | | | | News Article | History of Oppenheimer Variable Account Funds - Oppenheimer Main Street Fundva Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-21 | 2009-06-30 | N-CSRS | Dws Variable Series I - Dws Bond Vip | Specialty & Misc | | Sold All | -2,000 | -100 % | | | | -30.71 % | $9,780 | | | | | | News Article | History of Dws Variable Series I - Dws Bond Vip Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-21 | 2009-06-30 | N-CSR | Oppenheimer Main Street Small Cap Fund - Oppenheimer Main Street Small Cap Fund | Small-Cap Core | 100,640 | New Holding | 100,640 | 100 % | $1,602,189 | $1,110,059 | $-492,130 | -30.71 % | $-492,130 | | | | | | News Article | History of Oppenheimer Main Street Small Cap Fund - Oppenheimer Main Street Small Cap Fund Ownership Of Isis Pharmaceuticals Inc |
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