| Filed | As-Of/On | Form | Fullname | Fund Class | Shares | Activity | Shares Change | Shares Pct. Change | Hypothetical Old Value | Hypothetical New Value | Hypothetical Value Chg. | Hypotheticals Return |
Hypotheticals Results |
Director |
Other |
Ten Pct |
Officer |
Officer Title |
News Article |
History |
|---|
| 2009-11-06 | 2009-09-30 | 13F-HR | Am Sustainable Asset Management Ltd | Institution | 3,000 | New Holding | 3,000 | 100 % | $40,380 | $40,380 | $0 | 0.00 % | $0 | | | | | | News Article | History of Am Sustainable Asset Management Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Chwab Charles Investment Management Inc | Institution | 48,088 | Sold Some | -72,826 | -60.22 % | $647,264 | $647,264 | $0 | 0.00 % | $0 | | | | | | News Article | History of Chwab Charles Investment Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Credit Suisse First Boston | Institution | 45,491 | Sold Some | -92,767 | -67.09 % | $612,309 | $612,309 | $0 | 0.00 % | $0 | | | | | | News Article | History of Credit Suisse First Boston Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Genworth Financial Inc | Institution | 39 | New Holding | 39 | 100 % | $525 | $525 | $0 | 0.00 % | $0 | | | | | | News Article | History of Genworth Financial Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Hartford Investment Management Co | Institution | 275,526 | Added More | 22,000 | 8.67 % | $3,708,580 | $3,708,580 | $0 | 0.00 % | $0 | | | | | | News Article | History of Hartford Investment Management Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Metropolitan Life Insurance Co | Institution | 83,865 | No Change | 0 | 0 % | $1,128,823 | $1,128,823 | $0 | 0.00 % | $0 | | | | | | News Article | History of Metropolitan Life Insurance Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Pnc Financial Services Group Inc | Institution | 5,437 | Sold Some | -47,899 | -89.80 % | $73,182 | $73,182 | $0 | 0.00 % | $0 | | | | | | News Article | History of Pnc Financial Services Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Tcw Group Inc | Institution | 681,615 | Sold Some | -156,900 | -18.71 % | $9,174,538 | $9,174,538 | $0 | 0.00 % | $0 | | | | | | News Article | History of Tcw Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Teachers Advisors Inc | Institution | 181,674 | Sold Some | -33,931 | -15.73 % | $2,445,332 | $2,445,332 | $0 | 0.00 % | $0 | | | | | | News Article | History of Teachers Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Tiaa Cref Investment Management Llc | Institution | 587,202 | Sold Some | -126,351 | -17.70 % | $7,903,739 | $7,903,739 | $0 | 0.00 % | $0 | | | | | | News Article | History of Tiaa Cref Investment Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Unionbancal Corp | Institution | 3,400 | No Change | 0 | 0 % | $45,764 | $45,764 | $0 | 0.00 % | $0 | | | | | | News Article | History of Unionbancal Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-06 | 2009-09-30 | 13F-HR | Waddell And Reed Financial Inc | Institution | 1,789,550 | Added More | 250 | 0.01 % | $24,087,343 | $24,087,343 | $0 | 0.00 % | $0 | | | | | | News Article | History of Waddell And Reed Financial Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Campbell And Co Investment Adviser Llc | Institution | 93,884 | New Holding | 93,884 | 100 % | $1,272,128 | $1,263,679 | $-8,450 | -0.66 % | $-8,450 | | | | | | News Article | History of Campbell And Co Investment Adviser Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Cumberland Associates Llc | Institution | 170,000 | Sold Some | -40,000 | -19.04 % | $2,303,500 | $2,288,200 | $-15,300 | -0.66 % | $3,600 | | | | | | News Article | History of Cumberland Associates Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Old Mutual Asset Managers Uk Ltd | Institution | | Sold All | -118,028 | -100 % | | | | -0.66 % | $10,623 | | | | | | News Article | History of Old Mutual Asset Managers Uk Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Parametric Portfolio Associate | Institution | 38,961 | Added More | 2,448 | 6.70 % | $527,922 | $524,415 | $-3,506 | -0.66 % | $-220 | | | | | | News Article | History of Parametric Portfolio Associate Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Profund Advisors Llc | Institution | 16,332 | Added More | 680 | 4.34 % | $221,299 | $219,829 | $-1,470 | -0.66 % | $-61 | | | | | | News Article | History of Profund Advisors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Proshare Advisors Llc | Institution | 26,516 | Sold Some | -13,127 | -33.11 % | $359,292 | $356,905 | $-2,386 | -0.66 % | $1,181 | | | | | | News Article | History of Proshare Advisors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-09-30 | 13F-HR | Rafferty Asset Management Llc | Institution | 28,943 | No Change | 0 | 0 % | $392,178 | $389,573 | $-2,605 | -0.66 % | $0 | | | | | | News Article | History of Rafferty Asset Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-08-31 | N-CSR | Claymore Exchange Traded Fund Trust-Claymoreocean Tomo Growth Etf | Multi-Cap Growth | 208 | Added More | 25 | 13.66 % | $2,818 | $2,800 | $-19 | -0.66 % | $-2 | | | | | | News Article | History of Claymore Exchange Traded Fund Trust-Claymoreocean Tomo Growth Etf Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-05 | 2009-08-31 | N-CSR | Claymore Exchange Traded Fund Trust-Claymoreocean Tomo Patent Etf | Specialty & Misc | 103 | No Change | 0 | 0 % | $1,396 | $1,386 | $-9 | -0.66 % | $0 | | | | | | News Article | History of Claymore Exchange Traded Fund Trust-Claymoreocean Tomo Patent Etf Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-09-30 | 13F-HR | Atlas Browninc | Institution | 20,100 | New Holding | 20,100 | 100 % | $252,456 | $270,546 | $18,090 | 7.16 % | $18,090 | | | | | | News Article | History of Atlas Browninc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-09-30 | 13F-HR | Gw Capital Management Incco | Institution | 30,700 | Added More | 100 | 0.32 % | $385,592 | $413,222 | $27,630 | 7.16 % | $90 | | | | | | News Article | History of Gw Capital Management Incco Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-09-30 | 13F-HR | Ymphony Asset Management Llc | Institution | 581,749 | Added More | 229,457 | 65.13 % | $7,306,767 | $7,830,342 | $523,574 | 7.16 % | $206,511 | | | | | | News Article | History of Ymphony Asset Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-08-31 | N-CSR | Ga Funds-Ssga Enhanced Small Cap Fund | Small-Cap Core | 6,411 | Added More | 211 | 3.40 % | $80,522 | $86,292 | $5,770 | 7.16 % | $190 | | | | | | News Article | History of Ga Funds-Ssga Enhanced Small Cap Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-08-31 | N-CSRS | Gmo Trust-Gmo Value Fund | Multi-Cap Value | | Sold All | -200 | -100 % | | | | 7.16 % | $-180 | | | | | | News Article | History of Gmo Trust-Gmo Value Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-04 | 2009-08-31 | N-CSR | Legg Mason Partners Equity Trust-Legg Mason Partners Aggressive Growth Fund | Multi-Cap Growth | 952,000 | New Holding | 952,000 | 100 % | $11,957,120 | $12,813,920 | $856,800 | 7.16 % | $856,800 | | | | | | News Article | History of Legg Mason Partners Equity Trust-Legg Mason Partners Aggressive Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-03 | 2009-09-30 | 13F-HR | M And T Bank Corp | Institution | 350 | No Change | 0 | 0 % | $4,431 | $4,711 | $280 | 6.31 % | $0 | | | | | | News Article | History of M And T Bank Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-03 | 2009-09-30 | 13F-HR | Prudential Financial Inc | Institution | 723,545 | Sold Some | -205,200 | -22.09 % | $9,160,080 | $9,738,916 | $578,836 | 6.31 % | $-164,160 | | | | | | News Article | History of Prudential Financial Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-02 | 2009-09-30 | 13F-HR | Dowling And Yahnke Inc | Institution | 778,386 | No Change | 0 | 0 % | $9,636,419 | $10,477,076 | $840,657 | 8.72 % | $0 | | | | | | News Article | History of Dowling And Yahnke Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-02 | 2009-09-30 | 13F-HR | Emerald Advisers Inc | Institution | 179,610 | New Holding | 179,610 | 100 % | $2,223,572 | $2,417,551 | $193,979 | 8.72 % | $193,979 | | | | | | News Article | History of Emerald Advisers Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-02 | 2009-09-30 | 13F-HR | Emerald Mutual Fund Advisers Trust | Institution | 81,480 | New Holding | 81,480 | 100 % | $1,008,722 | $1,096,721 | $87,998 | 8.72 % | $87,998 | | | | | | News Article | History of Emerald Mutual Fund Advisers Trust Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-02 | 2009-09-30 | 13F-HR | Ghp Investment Advisors Inc | Institution | | Sold All | -250 | -100 % | | | | 8.72 % | $-270 | | | | | | News Article | History of Ghp Investment Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-11-02 | 2009-08-31 | N-CSRS | Fidelity Select Portfolios-Technology Portfolio | Science & Tech | 813,310 | Sold Some | -34,600 | -4.08 % | $10,068,778 | $10,947,153 | $878,375 | 8.72 % | $-37,368 | | | | | | News Article | History of Fidelity Select Portfolios-Technology Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-09-30 | 13F-HR | General Electric Co | Institution | 210,608 | No Change | 0 | 0 % | $2,668,403 | $2,834,784 | $166,380 | 6.23 % | $0 | | | | | | News Article | History of General Electric Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-09-30 | 13F-HR | Oxford Asset Management | Institution | | Sold All | -10,233 | -100 % | | | | 6.23 % | $-8,084 | | | | | | News Article | History of Oxford Asset Management Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-09-30 | 13F-HR/A | Perkins Capital Management Inc | Institution | 246,916 | Sold Some | -8,634 | -3.37 % | $3,128,426 | $3,323,489 | $195,064 | 6.23 % | $-6,821 | | | | | | News Article | History of Perkins Capital Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-09-30 | 13F-HR | Tocqueville Asset Management Lp | Institution | 1,440,220 | Added More | 31,725 | 2.25 % | $18,247,587 | $19,385,361 | $1,137,774 | 6.23 % | $25,063 | | | | | | News Article | History of Tocqueville Asset Management Lp Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Ei Institutional Investments Trust-Siit Large Cap Fund | Large-Cap Core | | Sold All | -4,600 | -100 % | | | | 6.23 % | $-3,634 | | | | | | News Article | History of Ei Institutional Investments Trust-Siit Large Cap Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Fidelity Advisor Series I-Growth Opportunities Fund | Large-Cap Core | 1,002,200 | Added More | 225,800 | 29.08 % | $12,697,874 | $13,489,612 | $791,738 | 6.23 % | $178,382 | | | | | | News Article | History of Fidelity Advisor Series I-Growth Opportunities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-CSRS | Fidelity Commonwealth Trust Ii-Fidelity Large Cap Growth Enhanced Index Fund | Large-Cap Growth | 2,000 | New Holding | 2,000 | 100 % | $25,340 | $26,920 | $1,580 | 6.23 % | $1,580 | | | | | | News Article | History of Fidelity Commonwealth Trust Ii-Fidelity Large Cap Growth Enhanced Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-CSRS | Fidelity Commonwealth Trust Ii-Fidelity Small Cap Enhanced Index Fund | Small-Cap Core | 8,000 | Sold Some | -16,500 | -67.34 % | $101,360 | $107,680 | $6,320 | 6.23 % | $-13,035 | | | | | | News Article | History of Fidelity Commonwealth Trust Ii-Fidelity Small Cap Enhanced Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Fidelity Commonwealth Trust-Fidelity Nasdaq Composite Index Tracking Stock | Specialty & Misc | 3,906 | No Compare | | | $49,489 | $52,575 | $3,086 | 6.23 % | | | | | | | News Article | History of Fidelity Commonwealth Trust-Fidelity Nasdaq Composite Index Tracking Stock Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Fidelity Mt Vernon Street Trust-Fidelity Aggressive Growth Fund | Multi-Cap Growth | 645,083 | Sold Some | -9,785,893 | -93.81 % | $8,173,202 | $8,682,817 | $509,616 | 6.23 % | $-7,730,855 | | | | | | News Article | History of Fidelity Mt Vernon Street Trust-Fidelity Aggressive Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Fidelity Mt Vernon Street Trust-Fidelity Growth Company Fund | Multi-Cap Growth | 9,812,981 | New Holding | 9,812,981 | 100 % | $124,330,469 | $132,082,724 | $7,752,255 | 6.23 % | $7,752,255 | | | | | | News Article | History of Fidelity Mt Vernon Street Trust-Fidelity Growth Company Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-Q | Fidelity Securities Fund-Agressive Growth Fund | Global Small/Mid-Cap Growth | 11,066 | New Holding | 11,066 | 100 % | $140,206 | $148,948 | $8,742 | 6.23 % | $8,742 | | | | | | News Article | History of Fidelity Securities Fund-Agressive Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-30 | 2009-08-31 | N-CSR | Vanguard World Fund-Vanguard Health Care Index Fund | Health/Biotech | 42,252 | New Holding | 42,252 | 100 % | $535,333 | $568,712 | $33,379 | 6.23 % | $33,379 | | | | | | News Article | History of Vanguard World Fund-Vanguard Health Care Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-29 | 2009-09-30 | 13F-HR | Dimensional Fund Advisors Inc | Institution | 684,619 | Sold Some | -28,849 | -4.04 % | $8,571,430 | $9,214,972 | $643,542 | 7.50 % | $-27,118 | | | | | | News Article | History of Dimensional Fund Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-29 | 2009-08-31 | N-Q | Usaa Mutual Funds Trust-Balanced Strategy Fund | Flexible Portfolio | 1,300 | New Holding | 1,300 | 100 % | $16,276 | $17,498 | $1,222 | 7.50 % | $1,222 | | | | | | News Article | History of Usaa Mutual Funds Trust-Balanced Strategy Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-29 | 2009-08-31 | N-Q | Usaa Mutual Funds Trust-Cornerstone Strategy Fund | Specialty & Misc | | Sold All | -5,200 | -100 % | | | | 7.50 % | $-4,888 | | | | | | News Article | History of Usaa Mutual Funds Trust-Cornerstone Strategy Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-29 | 2009-08-31 | N-Q | Valic Co I-Small Cap Index Fund | Small-Cap Core | 75,401 | New Holding | 75,401 | 100 % | $944,021 | $1,014,897 | $70,877 | 7.50 % | $70,877 | | | | | | News Article | History of Valic Co I-Small Cap Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-29 | 2009-08-31 | N-Q | Valic Co I-Value Fund | Multi-Cap Value | | Sold All | -31,443 | -100 % | | | | 7.50 % | $-29,556 | | | | | | News Article | History of Valic Co I-Value Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-28 | 2009-09-30 | 13F-HR | Davenport And Co Llc | Institution | 1,396,535 | Added More | 194,510 | 16.18 % | $17,191,346 | $18,797,361 | $1,606,015 | 9.34 % | $223,687 | | | | | | News Article | History of Davenport And Co Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-28 | 2009-09-30 | 13F-HR | Hirtle Callaghan Co Inc | Institution | 3,100 | No Compare | | | $38,161 | $41,726 | $3,565 | 9.34 % | | | | | | | News Article | History of Hirtle Callaghan Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-28 | 2009-09-30 | 13F-HR | Prentiss Smith And Co Inc | Institution | 200 | No Change | 0 | 0 % | $2,462 | $2,692 | $230 | 9.34 % | $0 | | | | | | News Article | History of Prentiss Smith And Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-28 | 2009-08-31 | N-Q | American Century Strategic Asset Allocations Inc-Newton Fund | Small-Cap Core | 19,037 | Added More | 2,388 | 14.34 % | $234,345 | $256,238 | $21,893 | 9.34 % | $2,746 | | | | | | News Article | History of American Century Strategic Asset Allocations Inc-Newton Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-27 | 2009-09-30 | 13F-HR | Essex Investment Management Co Llc | Institution | 2,113 | No Change | 0 | 0 % | $27,089 | $28,441 | $1,352 | 4.99 % | $0 | | | | | | News Article | History of Essex Investment Management Co Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-26 | 2009-08-31 | N-Q | Claymore Exchange Traded Fund Trust-Claymoremorningstar Services Super Sector Index Etf | Specialty & Misc | 45 | No Change | 0 | 0 % | $592 | $606 | $14 | 2.27 % | $0 | | | | | | News Article | History of Claymore Exchange Traded Fund Trust-Claymoremorningstar Services Super Sector Index Etf Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-22 | 2009-09-30 | 13F-HR | Blackrock Inc | No Data | | Sold All | -28,967 | -100 % | | | | -2.46 % | $9,849 | | | | | | News Article | History of Blackrock Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-15 | 2009-08-31 | N-Q | Allied Asset Advisors Funds-Allied Asset Advisor Fund | Specialty & Misc | 5,400 | New Holding | 5,400 | 100 % | $74,844 | $72,684 | $-2,160 | -2.88 % | $-2,160 | | | | | | News Article | History of Allied Asset Advisors Funds-Allied Asset Advisor Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-09 | 2009-07-31 | N-CSR | Advisors Inner Circle Fund Ii-Growth Fund | Small-Cap Growth | 102,790 | Added More | 57,670 | 127.81 % | $1,441,116 | $1,383,553 | $-57,562 | -3.99 % | $-32,295 | | | | | | News Article | History of Advisors Inner Circle Fund Ii-Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-07 | 2009-07-31 | N-CSR | Fidelity Advisor Series Vii-Fidelity Advisor Biotechnology Fund | Health/Biotech | 75,800 | Added More | 36,200 | 91.41 % | $1,052,104 | $1,020,268 | $-31,836 | -3.02 % | $-15,204 | | | | | | News Article | History of Fidelity Advisor Series Vii-Fidelity Advisor Biotechnology Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-07 | 2009-07-31 | N-CSR | Profunds-Bull Profund | Large-Cap Core | 3,392 | Added More | 1,680 | 98.13 % | $47,081 | $45,656 | $-1,425 | -3.02 % | $-706 | | | | | | News Article | History of Profunds-Bull Profund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-07 | 2009-07-31 | N-CSR | Profunds-Health Care Ultrasector Profund | Health/Biotech | 438 | Added More | 268 | 157.64 % | $6,079 | $5,895 | $-184 | -3.02 % | $-113 | | | | | | News Article | History of Profunds-Health Care Ultrasector Profund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-07 | 2009-07-31 | N-CSR | Profunds-Technology Ultrasector Profund | Science & Tech | 4,624 | New Holding | 4,624 | 100 % | $64,181 | $62,239 | $-1,942 | -3.02 % | $-1,942 | | | | | | News Article | History of Profunds-Technology Ultrasector Profund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-02 | 2009-07-31 | N-CSR | Old Mutual Advisor Funds-Old Mutual Copper Rock Emerging Growth Fund | Small-Cap Growth | | Sold All | -18,967 | -100 % | | | | -3.02 % | $7,966 | | | | | | News Article | History of Old Mutual Advisor Funds-Old Mutual Copper Rock Emerging Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-10-02 | 2009-07-31 | N-CSR | Usaa Mutual Funds Trust-Small Cap Stock Fund | Small-Cap Core | 115,200 | No Change | 0 | 0 % | $1,598,976 | $1,550,592 | $-48,384 | -3.02 % | $0 | | | | | | News Article | History of Usaa Mutual Funds Trust-Small Cap Stock Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | American Century Mutual Funds Inc-Balanced Fund | Mixed-Asset Target Allocation Growth | 11,304 | Added More | 234 | 2.11 % | $167,638 | $152,152 | $-15,486 | -9.23 % | $-321 | | | | | | News Article | History of American Century Mutual Funds Inc-Balanced Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | American Century Mutual Funds Inc-New Opportunities Fund | Small-Cap Growth | 29,946 | Sold Some | -2,258 | -7.01 % | $444,099 | $403,073 | $-41,026 | -9.23 % | $3,093 | | | | | | News Article | History of American Century Mutual Funds Inc-New Opportunities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | American Century Mutual Funds Inc-New Opportunities Ii | Small-Cap Growth | 103,415 | Sold Some | -16,819 | -13.98 % | $1,533,644 | $1,391,966 | $-141,679 | -9.23 % | $23,042 | | | | | | News Article | History of American Century Mutual Funds Inc-New Opportunities Ii Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dfa Investment Dimensions Group Inc-International Core Equity Portfolio | International Small-Mid-Cap Value | 58,097 | New Holding | 58,097 | 100 % | $861,579 | $781,986 | $-79,593 | -9.23 % | $-79,593 | | | | | | News Article | History of Dfa Investment Dimensions Group Inc-International Core Equity Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dfa Investment Dimensions Group Inc-International Vector Equity Portfolio | No Data | 10,070 | New Holding | 10,070 | 100 % | $149,338 | $135,542 | $-13,796 | -9.23 % | $-13,796 | | | | | | News Article | History of Dfa Investment Dimensions Group Inc-International Vector Equity Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dfa Investment Dimensions Group Inc-Us Sustainability Core 1 Portfolio | No Data | 900 | New Holding | 900 | 100 % | $13,347 | $12,114 | $-1,233 | -9.23 % | $-1,233 | | | | | | News Article | History of Dfa Investment Dimensions Group Inc-Us Sustainability Core 1 Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dws Balanced Fund-Dws Balanced Fund | Flexible Portfolio | | Sold All | -11,700 | -100 % | | | | -9.23 % | $16,029 | | | | | | News Article | History of Dws Balanced Fund-Dws Balanced Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dws Blue Chip Fund-Dws Blue Chip Fund | Multi-Cap Core | | Sold All | -5,500 | -100 % | | | | -9.23 % | $7,535 | | | | | | News Article | History of Dws Blue Chip Fund-Dws Blue Chip Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Dws Equity Trust-Dws Disciplined Longshort Growth Fund | Multi-Cap Growth | 2,000 | New Holding | 2,000 | 100 % | $29,660 | $26,920 | $-2,740 | -9.23 % | $-2,740 | | | | | | News Article | History of Dws Equity Trust-Dws Disciplined Longshort Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | First American Investment Funds Inc-Small Cap Growth Opportunities Fund | Small-Cap Growth | 85,962 | New Holding | 85,962 | 100 % | $1,274,816 | $1,157,049 | $-117,768 | -9.23 % | $-117,768 | | | | | | News Article | History of First American Investment Funds Inc-Small Cap Growth Opportunities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Ishares Trust-Ishares Morningstar Small Growth Index Fund | Small-Cap Growth | 30,768 | Added More | 6,042 | 24.43 % | $456,289 | $414,137 | $-42,152 | -9.23 % | $-8,278 | | | | | | News Article | History of Ishares Trust-Ishares Morningstar Small Growth Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Jnl Investors Series Trust-Jackson Perspective Index 5 Fund | Specialty & Misc | 1,101 | No Change | 0 | 0 % | $16,328 | $14,819 | $-1,508 | -9.23 % | $0 | | | | | | News Article | History of Jnl Investors Series Trust-Jackson Perspective Index 5 Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Russell Investment Co-International Fund | International Multi-Cap Core | | Sold All | -41,272 | -100 % | | | | -9.23 % | $56,543 | | | | | | News Article | History of Russell Investment Co-International Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-29 | 2009-07-31 | N-Q | Vanguard Explorer Fund-Vanguard Explorer Fund | Small-Cap Growth | 1,691,749 | Sold Some | -125,000 | -6.88 % | $25,088,638 | $22,770,942 | $-2,317,696 | -9.23 % | $171,250 | | | | | | News Article | History of Vanguard Explorer Fund-Vanguard Explorer Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Chwab Capital Trust-Schwab Health Care Fund | Health/Biotech | 50,000 | New Holding | 50,000 | 100 % | $752,500 | $673,000 | $-79,500 | -10.56 % | $-79,500 | | | | | | News Article | History of Chwab Capital Trust-Schwab Health Care Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Dryden Small Cap Core Equity Fund Inc-Dryden Small Cap Core Equity Fund Inc | Small-Cap Core | 7,200 | New Holding | 7,200 | 100 % | $108,360 | $96,912 | $-11,448 | -10.56 % | $-11,448 | | | | | | News Article | History of Dryden Small Cap Core Equity Fund Inc-Dryden Small Cap Core Equity Fund Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Dryden Tax Managed Funds-Dryden Large Cap Core Equity Fund | Large-Cap Core | 17,700 | New Holding | 17,700 | 100 % | $266,385 | $238,242 | $-28,143 | -10.56 % | $-28,143 | | | | | | News Article | History of Dryden Tax Managed Funds-Dryden Large Cap Core Equity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Fbr Funds-Fbr Pegasus Fund | Multi-Cap Value | 1,190 | New Holding | 1,190 | 100 % | $17,910 | $16,017 | $-1,892 | -10.56 % | $-1,892 | | | | | | News Article | History of Fbr Funds-Fbr Pegasus Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Massmutual Premier Funds-Massmutual Premier Main Street Small Cap Fund | Small-Cap Core | 2,460 | Sold Some | -280 | -10.21 % | $37,023 | $33,112 | $-3,911 | -10.56 % | $445 | | | | | | News Article | History of Massmutual Premier Funds-Massmutual Premier Main Street Small Cap Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Massmutual Premier Funds-Massmutual Premier Small Company Opportunities Fund | Small-Cap Core | 5,100 | No Change | 0 | 0 % | $76,755 | $68,646 | $-8,109 | -10.56 % | $0 | | | | | | News Article | History of Massmutual Premier Funds-Massmutual Premier Small Company Opportunities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Old Westbury Funds Inc-International Fund | International Multi-Cap Core | 10,035 | No Change | 0 | 0 % | $151,027 | $135,071 | $-15,956 | -10.56 % | $0 | | | | | | News Article | History of Old Westbury Funds Inc-International Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Powershares Exchange Traded Fund Trust-Powershares Dynamic Market Portfolio | Specialty & Misc | 268,102 | New Holding | 268,102 | 100 % | $4,034,935 | $3,608,653 | $-426,282 | -10.56 % | $-426,282 | | | | | | News Article | History of Powershares Exchange Traded Fund Trust-Powershares Dynamic Market Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Powershares Exchange-Traded Fund Trust Ii-Powershares Global Biotech Portfolio | No Data | 2,211 | Added More | 172 | 8.43 % | $33,276 | $29,760 | $-3,515 | -10.56 % | $-273 | | | | | | News Article | History of Powershares Exchange-Traded Fund Trust Ii-Powershares Global Biotech Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-28 | 2009-07-31 | N-Q | Tocqueville Trust-The Tocqueville Fund | Specialty & Misc | 250,000 | New Holding | 250,000 | 100 % | $3,762,500 | $3,365,000 | $-397,500 | -10.56 % | $-397,500 | | | | | | News Article | History of Tocqueville Trust-The Tocqueville Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-25 | 2009-07-31 | N-Q | Direxion Shares Etf Trust-Direxion Daily Small Cap Bull 3x Shares | No Data | 24,523 | Sold Some | -3,518 | -12.54 % | $357,055 | $330,080 | $-26,975 | -7.55 % | $3,870 | | | | | | News Article | History of Direxion Shares Etf Trust-Direxion Daily Small Cap Bull 3x Shares Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-25 | 2009-07-31 | N-Q | Mtb Group Of Funds-Mtb Multi Cap Growth Fund | Multi-Cap Core | | Sold All | -1,000 | -100 % | | | | -7.55 % | $1,100 | | | | | | News Article | History of Mtb Group Of Funds-Mtb Multi Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-25 | 2009-07-31 | N-Q | Mtb Group Of Funds-Mtb Small Cap Growth Fund | Small-Cap Growth | | Sold All | -65,324 | -100 % | | | | -7.55 % | $71,856 | | | | | | News Article | History of Mtb Group Of Funds-Mtb Small Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-17 | 2009-07-31 | N-Q | Rydex Etf Trust-Rydex Inverse Russell 2000 Etf | Specialty & Misc | 2,000 | New Holding | 2,000 | 100 % | $30,460 | $26,920 | $-3,540 | -11.62 % | $-3,540 | | | | | | News Article | History of Rydex Etf Trust-Rydex Inverse Russell 2000 Etf Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-15 | 2009-06-30 | N-CSRS/A | Wilshire Mutual Funds Inc-Wilshire Small Company Growth Portfolio | Small-Cap Growth | | Sold All | -129 | -100 % | | | | -13.27 % | $266 | | | | | | News Article | History of Wilshire Mutual Funds Inc-Wilshire Small Company Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-08 | 2009-06-30 | N-CSRS | Allianz Variable Insurance Products Trust-Azl Lmp Small Cap Growth Fund | Small-Cap Growth | | Sold All | -15,730 | -100 % | | | | -12.76 % | $30,988 | | | | | | News Article | History of Allianz Variable Insurance Products Trust-Azl Lmp Small Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-08 | 2009-06-30 | N-CSRS | Allianz Variable Insurance Products Trust-Azl Occ Opportunity Fund | Specialty & Misc | 71,100 | Added More | 10,975 | 18.25 % | $1,097,073 | $957,006 | $-140,067 | -12.76 % | $-21,621 | | | | | | News Article | History of Allianz Variable Insurance Products Trust-Azl Occ Opportunity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-08 | 2009-06-30 | N-CSRS | Rydex Series Funds-Banking Fund | Financial Services | 2,491 | Sold Some | -414 | -14.25 % | $38,436 | $33,529 | $-4,907 | -12.76 % | $816 | | | | | | News Article | History of Rydex Series Funds-Banking Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-08 | 2009-06-30 | N-CSRS | Rydex Variable Trust-Biotechnology Fund | Health/Biotech | 19,008 | Sold Some | -14,524 | -43.31 % | $293,293 | $255,848 | $-37,446 | -12.76 % | $28,612 | | | | | | News Article | History of Rydex Variable Trust-Biotechnology Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-08 | 2009-06-30 | N-CSRS | Timothy Plan-Timothy Aggressive Growth Fund | Multi-Cap Growth | | Sold All | -4,500 | -100 % | | | | -12.76 % | $8,865 | | | | | | News Article | History of Timothy Plan-Timothy Aggressive Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Advanced Series Trust-Ast Federated Aggressive Growth Portfolio | Multi-Cap Growth | 146,500 | Added More | 23,100 | 18.71 % | $2,267,820 | $1,971,890 | $-295,930 | -13.04 % | $-46,662 | | | | | | News Article | History of Advanced Series Trust-Ast Federated Aggressive Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Advanced Series Trust-Ast Pimco Total Return Bond Portfolio | Specialty & Misc | | Sold All | -27,300 | -100 % | | | | -13.04 % | $55,146 | | | | | | News Article | History of Advanced Series Trust-Ast Pimco Total Return Bond Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Advanced Series Trust-Ast Western Asset Core Plus Bond Portfolio | No Data | | Sold All | -7,700 | -100 % | | | | -13.04 % | $15,554 | | | | | | News Article | History of Advanced Series Trust-Ast Western Asset Core Plus Bond Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Axa Premier Vip Trust-Multimanager Small Cap Growth Portfolio | Small-Cap Growth | 51,500 | Sold Some | -16,800 | -24.59 % | $797,220 | $693,190 | $-104,030 | -13.04 % | $33,936 | | | | | | News Article | History of Axa Premier Vip Trust-Multimanager Small Cap Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Eq Advisors Trust-Eqalliancebernstein Small Cap Growth Portfolio | Small-Cap Growth | 59,600 | No Change | 0 | 0 % | $922,608 | $802,216 | $-120,392 | -13.04 % | $0 | | | | | | News Article | History of Eq Advisors Trust-Eqalliancebernstein Small Cap Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Eq Advisors Trust-Eqalliancebernstein Value Portfolio | Multi-Cap Value | 16,610 | New Holding | 16,610 | 100 % | $257,123 | $223,571 | $-33,552 | -13.04 % | $-33,552 | | | | | | News Article | History of Eq Advisors Trust-Eqalliancebernstein Value Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Eq Advisors Trust-Eqbond Index Portfolio | Specialty & Misc | 311,880 | Added More | 193,480 | 163.41 % | $4,827,902 | $4,197,905 | $-629,998 | -13.04 % | $-390,830 | | | | | | News Article | History of Eq Advisors Trust-Eqbond Index Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSR | Frontegra Funds Inc-Frontegra Ironbridge Smid Fund | Mid-Cap Core | | Sold All | -134,217 | -100 % | | | | -13.04 % | $271,118 | | | | | | News Article | History of Frontegra Funds Inc-Frontegra Ironbridge Smid Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSR | Jpmorgan Trust I-Jpmorgan Small Cap Core Fund | Small-Cap Core | 49 | New Holding | 49 | 100 % | $759 | $660 | $-99 | -13.04 % | $-99 | | | | | | News Article | History of Jpmorgan Trust I-Jpmorgan Small Cap Core Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSR | Jpmorgan Trust Ii-Jpmorgan Core Bond Fund | Multi-Cap Core | 49 | New Holding | 49 | 100 % | $759 | $660 | $-99 | -13.04 % | $-99 | | | | | | News Article | History of Jpmorgan Trust Ii-Jpmorgan Core Bond Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Profunds-Bull Profund | Large-Cap Core | 1,712 | Sold Some | -2,800 | -62.05 % | $26,502 | $23,044 | $-3,458 | -13.04 % | $5,656 | | | | | | News Article | History of Profunds-Bull Profund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Profunds-Profund Vp Biotechnology | Health/Biotech | 5,508 | New Holding | 5,508 | 100 % | $85,264 | $74,138 | $-11,126 | -13.04 % | $-11,126 | | | | | | News Article | History of Profunds-Profund Vp Biotechnology Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Profunds-Profund Vp Health Care | Health/Biotech | 3,024 | Added More | 1,534 | 102.95 % | $46,812 | $40,703 | $-6,108 | -13.04 % | $-3,099 | | | | | | News Article | History of Profunds-Profund Vp Health Care Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Un Capital Advisers Trust-Sc Aim Small Cap Growth Fund | No Data | 3,966 | Added More | 1,866 | 88.85 % | $61,394 | $53,382 | $-8,011 | -13.04 % | $-3,769 | | | | | | News Article | History of Un Capital Advisers Trust-Sc Aim Small Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Un Capital Advisers Trust-Sc Oppenheimer Main Street Small Cap Fund | Small-Cap Core | 4,780 | Added More | 3,580 | 298.33 % | $73,994 | $64,339 | $-9,656 | -13.04 % | $-7,232 | | | | | | News Article | History of Un Capital Advisers Trust-Sc Oppenheimer Main Street Small Cap Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Vanguard Institutional Index Funds-Vanguard Institutional Index Fund | Specialty & Misc | 84,307 | New Holding | 84,307 | 100 % | $1,305,072 | $1,134,772 | $-170,300 | -13.04 % | $-170,300 | | | | | | News Article | History of Vanguard Institutional Index Funds-Vanguard Institutional Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-04 | 2009-06-30 | N-CSRS | Vanguard Variable Insurance Funds-Small Company Growth Portfolio | Small-Cap Growth | 264,750 | New Holding | 264,750 | 100 % | $4,098,330 | $3,563,535 | $-534,795 | -13.04 % | $-534,795 | | | | | | News Article | History of Vanguard Variable Insurance Funds-Small Company Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSR | American Century Quantitative Equity Funds Inc-Utilities Fund | Utility | | Sold All | -35,321 | -100 % | | | | - % | | | | | | | News Article | History of American Century Quantitative Equity Funds Inc-Utilities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSRS | Jnl Variable Fund Llc-Jnlmcm Healthcare Sector Fund | Health/Biotech | 9 | No Change | 0 | 0 % | | $121 | | - % | | | | | | | News Article | History of Jnl Variable Fund Llc-Jnlmcm Healthcare Sector Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSRS | Mml Series Investment Fund Ii-Mml Small Cap Equity Fund | Small-Cap Core | 3,930 | Added More | 3,160 | 410.38 % | | $52,898 | | - % | | | | | | | News Article | History of Mml Series Investment Fund Ii-Mml Small Cap Equity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSRS | Ohio National Fund Inc-Bryton Growth Portfolio | Multi-Cap Growth | | Sold All | -45,000 | -100 % | | | | - % | | | | | | | News Article | History of Ohio National Fund Inc-Bryton Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSRS | Pacific Select Fund-Pd Small-Cap Growth Index Portfolio | No Data | 3,218 | No Compare | | | | $43,314 | | - % | | | | | | | News Article | History of Pacific Select Fund-Pd Small-Cap Growth Index Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-03 | 2009-06-30 | N-CSR | Treettracks Series Trust-Spdr Dividend Etf | Specialty & Misc | | Sold All | -1,392,533 | -100 % | | | | - % | | | | | | | News Article | History of Treettracks Series Trust-Spdr Dividend Etf Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-02 | 2009-06-30 | N-CSRS | Met Investors Series Trust-Metaim Small Cap Growth Portfolio | Small-Cap Growth | 220,683 | Added More | 44,283 | 25.10 % | $3,427,207 | $2,970,393 | $-456,814 | -13.32 % | $-91,666 | | | | | | News Article | History of Met Investors Series Trust-Metaim Small Cap Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-09-01 | 2009-06-30 | N-Q/A | Rydex Series Funds-Biotechnology Fund | Health/Biotech | 116,772 | Added More | 11,009 | 10.40 % | $1,832,153 | $1,571,751 | $-260,402 | -14.21 % | $-24,550 | | | | | | News Article | History of Rydex Series Funds-Biotechnology Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-31 | 2009-06-30 | N-Q | Ei Institutional Managed Trust-Large Cap Diversified Alpha Fund | Large-Cap Core | 9,900 | New Holding | 9,900 | 100 % | $159,786 | $133,254 | $-26,532 | -16.60 % | $-26,532 | | | | | | News Article | History of Ei Institutional Managed Trust-Large Cap Diversified Alpha Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-31 | 2009-06-30 | N-CSRS | Mutual Of America Investment Corp-Bond Fund | Specialty & Misc | 45,913 | Added More | 393 | 0.86 % | $741,036 | $617,989 | $-123,047 | -16.60 % | $-1,053 | | | | | | News Article | History of Mutual Of America Investment Corp-Bond Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-31 | 2009-06-30 | N-CSRS | Tiaa Cref Life Fund-Stock Index Fund | Specialty & Misc | 1,170 | No Change | 0 | 0 % | $18,884 | $15,748 | $-3,136 | -16.60 % | $0 | | | | | | News Article | History of Tiaa Cref Life Fund-Stock Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-CSR | Allianz Funds-Occ Value | Large-Cap Value | 114,650 | Added More | 15,975 | 16.18 % | $1,851,598 | $1,543,189 | $-308,409 | -16.65 % | $-42,973 | | | | | | News Article | History of Allianz Funds-Occ Value Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Calvert Social Investment Fund-Equity Portfolio | Multi-Cap Core | 1,800 | New Holding | 1,800 | 100 % | $29,070 | $24,228 | $-4,842 | -16.65 % | $-4,842 | | | | | | News Article | History of Calvert Social Investment Fund-Equity Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-CSRS | Columbia Funds Variable Insurance Trust-Columbia Asset Allocation Fund Variable Serie | Specialty & Misc | 790 | New Holding | 790 | 100 % | $12,759 | $10,633 | $-2,125 | -16.65 % | $-2,125 | | | | | | News Article | History of Columbia Funds Variable Insurance Trust-Columbia Asset Allocation Fund Variable Serie Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-CSRS | Columbia Funds Variable Insurance Trust-Columbia Small Company Growth Fund Variable Serie | Small-Cap Growth | 13,900 | New Holding | 13,900 | 100 % | $224,485 | $187,094 | $-37,391 | -16.65 % | $-37,391 | | | | | | News Article | History of Columbia Funds Variable Insurance Trust-Columbia Small Company Growth Fund Variable Serie Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-CSRS | Dws Variable Series Ii-Dws Balanced Vip | Flexible Portfolio | | Sold All | -11,000 | -100 % | | | | -16.65 % | $29,590 | | | | | | News Article | History of Dws Variable Series Ii-Dws Balanced Vip Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-CSRS | Dws Variable Series Ii-Dws Blue Chip Vip | Specialty & Misc | | Sold All | -2,200 | -100 % | | | | -16.65 % | $5,918 | | | | | | News Article | History of Dws Variable Series Ii-Dws Blue Chip Vip Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Easons Series Trust-Stock Portfolio | Multi-Cap Core | 2,033 | New Holding | 2,033 | 100 % | $32,833 | $27,364 | $-5,469 | -16.65 % | $-5,469 | | | | | | News Article | History of Easons Series Trust-Stock Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ishares Trust-Ishares Nasdaq Biotechnology Index Fund | Health/Biotech | 835,965 | Sold Some | -44,222 | -5.02 % | $13,500,835 | $11,252,089 | $-2,248,746 | -16.65 % | $118,957 | | | | | | News Article | History of Ishares Trust-Ishares Nasdaq Biotechnology Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ishares Trust-Ishares Russell 2000 Growth Index Fund | Multi-Cap Growth | 659,658 | Added More | 46,218 | 7.53 % | $10,653,477 | $8,878,997 | $-1,774,480 | -16.65 % | $-124,326 | | | | | | News Article | History of Ishares Trust-Ishares Russell 2000 Growth Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ishares Trust-Ishares Russell 2000 Index Fund | Specialty & Misc | 1,123,453 | Added More | 6,401 | 0.57 % | $18,143,766 | $15,121,677 | $-3,022,089 | -16.65 % | $-17,219 | | | | | | News Article | History of Ishares Trust-Ishares Russell 2000 Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ishares Trust-Ishares Russell 3000 Growth Index Fund | Multi-Cap Growth | 5,887 | Sold Some | -319 | -5.14 % | $95,075 | $79,239 | $-15,836 | -16.65 % | $858 | | | | | | News Article | History of Ishares Trust-Ishares Russell 3000 Growth Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ishares Trust-Ishares Russell 3000 Index Fund | Specialty & Misc | 26,394 | Added More | 1,560 | 6.28 % | $426,263 | $355,263 | $-71,000 | -16.65 % | $-4,196 | | | | | | News Article | History of Ishares Trust-Ishares Russell 3000 Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Loomis Sayles Funds I-Loomis Sayles Bond Fund | Specialty & Misc | | Sold All | -49,143 | -100 % | | | | -16.65 % | $132,195 | | | | | | News Article | History of Loomis Sayles Funds I-Loomis Sayles Bond Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Loomis Sayles Funds Ii-Loomis Sayles Small Cap Growth Fund | Small-Cap Growth | 48,621 | Sold Some | -522 | -1.06 % | $785,229 | $654,439 | $-130,790 | -16.65 % | $1,404 | | | | | | News Article | History of Loomis Sayles Funds Ii-Loomis Sayles Small Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Riversource Strategic Allocation Series Inc-Riversource Strategic Allocation Fund | Flexible Portfolio | 25,688 | New Holding | 25,688 | 100 % | $414,861 | $345,760 | $-69,101 | -16.65 % | $-69,101 | | | | | | News Article | History of Riversource Strategic Allocation Series Inc-Riversource Strategic Allocation Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Riversource Strategy Series Inc-Riversource Small Cap Growth Fund | Small-Cap Growth | 12,100 | New Holding | 12,100 | 100 % | $195,415 | $162,866 | $-32,549 | -16.65 % | $-32,549 | | | | | | News Article | History of Riversource Strategy Series Inc-Riversource Small Cap Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2009-06-30 | N-Q | Ti Classic Funds-Small Cap Growth Stock Fund | Small-Cap Growth | 137,990 | Sold Some | -5,280 | -3.68 % | $2,228,539 | $1,857,345 | $-371,193 | -16.65 % | $14,203 | | | | | | News Article | History of Ti Classic Funds-Small Cap Growth Stock Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2008-06-30 | N-Q | Vanguard Horizon Funds-Vanguard Strategic Equity Fund | Specialty & Misc | 1,525,802 | New Holding | 1,525,802 | 100 % | $24,641,702 | $20,537,295 | $-4,104,407 | -16.65 % | $-4,104,407 | | | | | | News Article | History of Vanguard Horizon Funds-Vanguard Strategic Equity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-28 | 2008-06-30 | N-Q | Vanguard Horizon Funds-Vanguard Strategic Small-Cap Equity Fund | Small-Cap Core | 52,000 | New Holding | 52,000 | 100 % | $839,800 | $699,920 | $-139,880 | -16.65 % | $-139,880 | | | | | | News Article | History of Vanguard Horizon Funds-Vanguard Strategic Small-Cap Equity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Dws Advisor Funds-Dws Lifecycle Long Range Fund | Mixed-Asset Target Allocation Moderate | 3,800 | New Holding | 3,800 | 100 % | $62,586 | $51,148 | $-11,438 | -18.27 % | $-11,438 | | | | | | News Article | History of Dws Advisor Funds-Dws Lifecycle Long Range Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Ivy Funds Inc-Ivy Science And Technology Fund | Science & Tech | 483 | Added More | 182 | 60.46 % | $7,955 | $6,501 | $-1,454 | -18.27 % | $-548 | | | | | | News Article | History of Ivy Funds Inc-Ivy Science And Technology Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Leuthold Funds Inc-Leuthold Core Investment Fund | Flexible Portfolio | 273,520 | Added More | 72,650 | 36.16 % | $4,504,874 | $3,681,579 | $-823,295 | -18.27 % | $-218,677 | | | | | | News Article | History of Leuthold Funds Inc-Leuthold Core Investment Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Leuthold Funds Inc-Leuthold Select Industries Fund | Specialty Dvsfd Eq | 14,808 | Added More | 3,095 | 26.42 % | $243,888 | $199,316 | $-44,572 | -18.27 % | $-9,316 | | | | | | News Article | History of Leuthold Funds Inc-Leuthold Select Industries Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Old Mutual Advisor Funds Ii-Old Mutual Strategic Small Company Fund | Small-Cap Core | | Sold All | -8,560 | -100 % | | | | -18.27 % | $25,766 | | | | | | News Article | History of Old Mutual Advisor Funds Ii-Old Mutual Strategic Small Company Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Tiaa Cref Institutional Mutual Funds-Equity Index Fund | Specialty & Misc | 62,921 | Added More | 40,598 | 181.86 % | $1,036,309 | $846,917 | $-189,392 | -18.27 % | $-122,200 | | | | | | News Article | History of Tiaa Cref Institutional Mutual Funds-Equity Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-Q | Tiaa Cref Institutional Mutual Funds-Growth Equity Fund | Multi-Cap Growth | | Sold All | -32,113 | -100 % | | | | -18.27 % | $96,660 | | | | | | News Article | History of Tiaa Cref Institutional Mutual Funds-Growth Equity Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-CSRS | Vanguard Index Funds-Vanguard Extended Market Index Fund | Mid-Cap Core | 596,740 | New Holding | 596,740 | 100 % | $9,828,308 | $8,032,120 | $-1,796,187 | -18.27 % | $-1,796,187 | | | | | | News Article | History of Vanguard Index Funds-Vanguard Extended Market Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-CSRS | Vanguard Index Funds-Vanguard Growth Index Fund | Large-Cap Growth | 715,561 | New Holding | 715,561 | 100 % | $11,785,290 | $9,631,451 | $-2,153,839 | -18.27 % | $-2,153,839 | | | | | | News Article | History of Vanguard Index Funds-Vanguard Growth Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2009-06-30 | N-CSRS | Vanguard Index Funds-Vanguard Total Stock Market Index Fund | Multi-Cap Core | 894,367 | New Holding | 894,367 | 100 % | $14,730,224 | $12,038,180 | $-2,692,045 | -18.27 % | $-2,692,045 | | | | | | News Article | History of Vanguard Index Funds-Vanguard Total Stock Market Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2008-06-30 | N-CSRS | Vanguard Balanced Index Funds-Vanguard Balanced Index Fund | Mixed-Asset Target Allocation Growth | 36,225 | Added More | 2,725 | 8.13 % | $596,626 | $487,589 | $-109,037 | -18.27 % | $-8,202 | | | | | | News Article | History of Vanguard Balanced Index Funds-Vanguard Balanced Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-27 | 2008-06-30 | N-CSRS | Vanguard Balanced Index Funds-Vanguard Balanced Index Fund | Mixed-Asset Target Allocation Growth | 43,625 | Added More | 10,125 | 30.22 % | $718,504 | $587,193 | $-131,311 | -18.27 % | $-30,476 | | | | | | News Article | History of Vanguard Balanced Index Funds-Vanguard Balanced Index Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-26 | 2009-06-30 | N-Q | Vanguard Quantitative Funds-Vanguard Structured Broad Market | Multi-Cap Core | | Sold All | -20,030 | -100 % | | | | -17.27 % | $56,284 | | | | | | News Article | History of Vanguard Quantitative Funds-Vanguard Structured Broad Market Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-25 | 2009-06-30 | N-CSRS | Maxim Series Fund Inc-Maxim Small-Cap Growth Portfolio | No Data | 30,600 | New Holding | 30,600 | 100 % | $489,600 | $411,876 | $-77,724 | -15.87 % | $-77,724 | | | | | | News Article | History of Maxim Series Fund Inc-Maxim Small-Cap Growth Portfolio Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-25 | 2009-06-30 | N-Q | Oppenheimer Global Opportunities Fund-Oppenheimer Global Opportunities Fund | Global Flex Port | | Sold All | -3,000,000 | -100 % | | | | -15.87 % | $7,620,000 | | | | | | News Article | History of Oppenheimer Global Opportunities Fund-Oppenheimer Global Opportunities Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-24 | 2009-06-30 | N-CSRS | Genworth Variable Insurance Trust-Genworth Legg Mason Partners Aggressive Growth Fund | No Data | 14,620 | No Compare | | | $233,920 | $196,785 | $-37,135 | -15.87 % | | | | | | | News Article | History of Genworth Variable Insurance Trust-Genworth Legg Mason Partners Aggressive Growth Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-24 | 2009-06-30 | N-CSRS | Oppenheimer Variable Account Funds-Oppenheimer Main Street Fundva | Specialty & Misc | 23,600 | New Holding | 23,600 | 100 % | $377,600 | $317,656 | $-59,944 | -15.87 % | $-59,944 | | | | | | News Article | History of Oppenheimer Variable Account Funds-Oppenheimer Main Street Fundva Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-21 | 2009-06-30 | N-CSRS | Dws Variable Series I-Dws Bond Vip | Specialty & Misc | | Sold All | -2,000 | -100 % | | | | -15.45 % | $4,920 | | | | | | News Article | History of Dws Variable Series I-Dws Bond Vip Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-21 | 2009-06-30 | N-CSR | Oppenheimer Main Street Small Cap Fund-Oppenheimer Main Street Small Cap Fund | Small-Cap Core | 100,640 | New Holding | 100,640 | 100 % | $1,602,189 | $1,354,614 | $-247,574 | -15.45 % | $-247,574 | | | | | | News Article | History of Oppenheimer Main Street Small Cap Fund-Oppenheimer Main Street Small Cap Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-19 | 2009-06-30 | N-CSRS | Mutual Of America Institutional Funds Inc-Bond Fund | Specialty & Misc | 859 | Added More | 43 | 5.26 % | $13,332 | $11,562 | $-1,770 | -13.27 % | $-89 | | | | | | News Article | History of Mutual Of America Institutional Funds Inc-Bond Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-18 | 2009-06-30 | 13F-HR/A | Barclays Global Investors Uk Holdings Ltd | Institution | 5,254,572 | Added More | 329,801 | 6.69 % | $80,342,406 | $70,726,539 | $-9,615,867 | -11.96 % | $-603,536 | | | | | | News Article | History of Barclays Global Investors Uk Holdings Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-18 | 2009-06-30 | 13F-HR | Us Bancorp De | Institution | 400 | No Change | 0 | 0 % | $6,116 | $5,384 | $-732 | -11.96 % | $0 | | | | | | News Article | History of Us Bancorp De Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-17 | 2009-06-30 | 13F-HR | Boston Trust And Investment Management Co | Institution | | Sold All | -522 | -100 % | | | | -12.14 % | $971 | | | | | | News Article | History of Boston Trust And Investment Management Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-17 | 2009-06-30 | 13F-HR | Garrison Bradford And Associates Inc | Institution | 30,500 | Sold Some | -3,000 | -8.95 % | $467,260 | $410,530 | $-56,730 | -12.14 % | $5,580 | | | | | | News Article | History of Garrison Bradford And Associates Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-17 | 2009-06-30 | 13F-HR | Madison Square Investors Llc | No Data | 84,257 | Added More | 23,120 | 37.81 % | $1,290,817 | $1,134,099 | $-156,718 | -12.14 % | $-43,003 | | | | | | News Article | History of Madison Square Investors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-17 | 2009-06-30 | 13F-HR | Morgan Stanley | Institution | 1,002,930 | Sold Some | -337,523 | -25.17 % | $15,364,888 | $13,499,438 | $-1,865,450 | -12.14 % | $627,793 | | | | | | News Article | History of Morgan Stanley Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | American International Group Inc | Institution | 76,889 | Added More | 2,249 | 3.01 % | $1,205,620 | $1,034,926 | $-170,694 | -14.15 % | $-4,993 | | | | | | News Article | History of American International Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Axa | Institution | 573,185 | Added More | 129,271 | 29.12 % | $8,987,541 | $7,715,070 | $-1,272,471 | -14.15 % | $-286,982 | | | | | | News Article | History of Axa Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Bam Management Llc | No Data | 30,050 | New Holding | 30,050 | 100 % | $471,184 | $404,473 | $-66,711 | -14.15 % | $-66,711 | | | | | | News Article | History of Bam Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Batterymarch Financial Management Inc | Institution | 228,909 | Sold Some | -12,320 | -5.10 % | $3,589,293 | $3,081,115 | $-508,178 | -14.15 % | $27,350 | | | | | | News Article | History of Batterymarch Financial Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Bnp Paribas Arbitrage Sa | Institution | 13,606 | Sold Some | -8,951 | -39.68 % | $213,342 | $183,137 | $-30,205 | -14.15 % | $19,871 | | | | | | News Article | History of Bnp Paribas Arbitrage Sa Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Caxton Associates Llc | Institution | 22,836 | Sold Some | -5,673 | -19.89 % | $358,068 | $307,373 | $-50,696 | -14.15 % | $12,594 | | | | | | News Article | History of Caxton Associates Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Citadel L P | Institution | 747 | Sold Some | -265,845 | -99.71 % | $11,713 | $10,055 | $-1,658 | -14.15 % | $590,176 | | | | | | News Article | History of Citadel L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Citigroup Inc | Institution | 256,870 | Sold Some | -22,404 | -8.02 % | $4,027,722 | $3,457,470 | $-570,251 | -14.15 % | $49,737 | | | | | | News Article | History of Citigroup Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Clearbridge Advisors Llc | Institution | 2,349,252 | Sold Some | -122,186 | -4.94 % | $36,836,271 | $31,620,932 | $-5,215,339 | -14.15 % | $271,253 | | | | | | News Article | History of Clearbridge Advisors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Dekabank Deutsche Girozentrale | No Data | 177,000 | New Holding | 177,000 | 100 % | $2,775,360 | $2,382,420 | $-392,940 | -14.15 % | $-392,940 | | | | | | News Article | History of Dekabank Deutsche Girozentrale Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Diker Management Llc | Institution | 603,209 | Sold Some | -172,946 | -22.28 % | $9,458,317 | $8,119,193 | $-1,339,124 | -14.15 % | $383,940 | | | | | | News Article | History of Diker Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Ei Trust Co | Institution | 4,540 | Added More | 1,210 | 36.33 % | $71,187 | $61,108 | $-10,079 | -14.15 % | $-2,686 | | | | | | News Article | History of Ei Trust Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Employees Retirement System Of Texa | Institution | 204,400 | Sold Some | -13,000 | -5.97 % | $3,204,992 | $2,751,224 | $-453,768 | -14.15 % | $28,860 | | | | | | News Article | History of Employees Retirement System Of Texa Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Fidelity International Ltd | Institution | 3,580 | New Holding | 3,580 | 100 % | $56,134 | $48,187 | $-7,948 | -14.15 % | $-7,948 | | | | | | News Article | History of Fidelity International Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Fifth Third Bancorp | Institution | 251 | No Change | 0 | 0 % | $3,936 | $3,378 | $-557 | -14.15 % | $0 | | | | | | News Article | History of Fifth Third Bancorp Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Fmr Corp | Institution | 14,715,972 | Added More | 439,215 | 3.07 % | $230,746,441 | $198,076,983 | $-32,669,458 | -14.15 % | $-975,057 | | | | | | News Article | History of Fmr Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Geode Capital Management Llc | Institution | 358,725 | Sold Some | -21,495 | -5.65 % | $5,624,808 | $4,828,439 | $-796,370 | -14.15 % | $47,719 | | | | | | News Article | History of Geode Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Goldman Sachs Group Inc | Institution | 856,231 | Added More | 381,360 | 80.30 % | $13,425,702 | $11,524,869 | $-1,900,833 | -14.15 % | $-846,619 | | | | | | News Article | History of Goldman Sachs Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Haw D E And Co Inc | Institution | 275,076 | Added More | 181,079 | 192.64 % | $4,313,192 | $3,702,523 | $-610,669 | -14.15 % | $-401,995 | | | | | | News Article | History of Haw D E And Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Ing Groep Nv | Institution | 87,200 | Sold Some | -86,000 | -49.65 % | $1,367,296 | $1,173,712 | $-193,584 | -14.15 % | $190,920 | | | | | | News Article | History of Ing Groep Nv Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Jacobs Levy Equity Management Inc | Institution | 649,993 | Added More | 455,397 | 234.02 % | $10,191,890 | $8,748,906 | $-1,442,984 | -14.15 % | $-1,010,981 | | | | | | News Article | History of Jacobs Levy Equity Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Jane Street Holding Llc | Institution | 13,192 | New Holding | 13,192 | 100 % | $206,851 | $177,564 | $-29,286 | -14.15 % | $-29,286 | | | | | | News Article | History of Jane Street Holding Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Jefferies Group Inc | Institution | | Sold All | -13,700 | -100 % | | | | -14.15 % | $30,414 | | | | | | News Article | History of Jefferies Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Kbc Group Nv | Institution | 24,380 | Sold Some | -6,727 | -21.62 % | $382,278 | $328,155 | $-54,124 | -14.15 % | $14,934 | | | | | | News Article | History of Kbc Group Nv Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Labranche And Co Inc | Institution | | Sold All | -26,486 | -100 % | | | | -14.15 % | $58,799 | | | | | | News Article | History of Labranche And Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Leuthold Weeden Capital Management Llc | Institution | 456,979 | Added More | 108,969 | 31.31 % | $7,165,431 | $6,150,937 | $-1,014,493 | -14.15 % | $-241,911 | | | | | | News Article | History of Leuthold Weeden Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Loomis Sayles And Co L P | Institution | 145,715 | Sold Some | -13,774 | -8.63 % | $2,284,811 | $1,961,324 | $-323,487 | -14.15 % | $30,578 | | | | | | News Article | History of Loomis Sayles And Co L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Managed Account Advisors Llc | Institution | 455 | New Holding | 455 | 100 % | $7,134 | $6,124 | $-1,010 | -14.15 % | $-1,010 | | | | | | News Article | History of Managed Account Advisors Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Martingale Asset Management L P | Institution | 76,900 | Added More | 1,000 | 1.31 % | $1,205,792 | $1,035,074 | $-170,718 | -14.15 % | $-2,220 | | | | | | News Article | History of Martingale Asset Management L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Merrill Lynch And Co Inc | Institution | 185,061 | New Holding | 185,061 | 100 % | $2,901,756 | $2,490,921 | $-410,835 | -14.15 % | $-410,835 | | | | | | News Article | History of Merrill Lynch And Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | New York State Common Retirement Fund | Institution | 30,780 | Sold Some | -6,900 | -18.31 % | $482,630 | $414,299 | $-68,332 | -14.15 % | $15,318 | | | | | | News Article | History of New York State Common Retirement Fund Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Nomura Asset Management Co Ltd | Institution | 349,500 | Added More | 238,000 | 213.45 % | $5,480,160 | $4,704,270 | $-775,890 | -14.15 % | $-528,360 | | | | | | News Article | History of Nomura Asset Management Co Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Northern Trust Co Of Connecticut | Institution | 40,575 | Sold Some | -21,561 | -34.69 % | $636,216 | $546,140 | $-90,077 | -14.15 % | $47,865 | | | | | | News Article | History of Northern Trust Co Of Connecticut Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Northern Trust Corp | Institution | 1,056,385 | Added More | 178,969 | 20.39 % | $16,564,117 | $14,218,942 | $-2,345,175 | -14.15 % | $-397,311 | | | | | | News Article | History of Northern Trust Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Oppenheimer Funds Inc | Institution | 3,151,460 | Added More | 72,330 | 2.34 % | $49,414,893 | $42,418,652 | $-6,996,241 | -14.15 % | $-160,573 | | | | | | News Article | History of Oppenheimer Funds Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Pergamon Offshore Advisors L P | Institution | 66,065 | Sold Some | -3,451 | -4.96 % | $1,035,899 | $889,235 | $-146,664 | -14.15 % | $7,661 | | | | | | News Article | History of Pergamon Offshore Advisors L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Perimeter Capital Partners Llc | Institution | 281,000 | New Holding | 281,000 | 100 % | $4,406,080 | $3,782,260 | $-623,820 | -14.15 % | $-623,820 | | | | | | News Article | History of Perimeter Capital Partners Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Price T Rowe Associates Inc | Institution | 49,485 | Added More | 4,400 | 9.75 % | $775,925 | $666,068 | $-109,857 | -14.15 % | $-9,768 | | | | | | News Article | History of Price T Rowe Associates Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Principal Financial Group Inc | Institution | 369,790 | Sold Some | -210 | -0.05 % | $5,798,307 | $4,977,373 | $-820,934 | -14.15 % | $466 | | | | | | News Article | History of Principal Financial Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Rbc Dain Rauscher Inc | Institution | 232,363 | Sold Some | -5,079 | -2.13 % | $3,643,452 | $3,127,606 | $-515,846 | -14.15 % | $11,275 | | | | | | News Article | History of Rbc Dain Rauscher Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Rothschild Asset Management Inc | Institution | 806,207 | Sold Some | -46,582 | -5.46 % | $12,641,326 | $10,851,546 | $-1,789,780 | -14.15 % | $103,412 | | | | | | News Article | History of Rothschild Asset Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Royal Bank Of Canada | Institution | 500 | New Holding | 500 | 100 % | $7,840 | $6,730 | $-1,110 | -14.15 % | $-1,110 | | | | | | News Article | History of Royal Bank Of Canada Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Russell Frank Co | Institution | 210,999 | Added More | 63,886 | 43.42 % | $3,308,464 | $2,840,047 | $-468,418 | -14.15 % | $-141,827 | | | | | | News Article | History of Russell Frank Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Thales Fund Management Llc | Institution | | Sold All | -600 | -100 % | | | | -14.15 % | $1,332 | | | | | | News Article | History of Thales Fund Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Trategic Investment Management | Institution | 22,884 | Sold Some | -8,426 | -26.91 % | $358,821 | $308,019 | $-50,802 | -14.15 % | $18,706 | | | | | | News Article | History of Trategic Investment Management Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Two Sigma Investments Llc | Institution | | Sold All | -21,680 | -100 % | | | | -14.15 % | $48,130 | | | | | | News Article | History of Two Sigma Investments Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Vanguard Group Inc | Institution | 5,671,182 | Added More | 274,225 | 5.08 % | $88,924,134 | $76,334,110 | $-12,590,024 | -14.15 % | $-608,780 | | | | | | News Article | History of Vanguard Group Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-14 | 2009-06-30 | 13F-HR | Zebra Capital Management Llc | Institution | | Sold All | -200 | -100 % | | | | -14.15 % | $444 | | | | | | News Article | History of Zebra Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Allstate Insurance Co | Institution | 90,000 | Sold Some | -43,620 | -32.64 % | $1,442,700 | $1,211,400 | $-231,300 | -16.03 % | $112,103 | | | | | | News Article | History of Allstate Insurance Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Allstate Retirement Plan | Institution | | Sold All | -22,730 | -100 % | | | | -16.03 % | $58,416 | | | | | | News Article | History of Allstate Retirement Plan Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Ameriprise Financial Inc | Institution | 158,548 | Added More | 25,768 | 19.40 % | $2,541,524 | $2,134,056 | $-407,468 | -16.03 % | $-66,224 | | | | | | News Article | History of Ameriprise Financial Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Bank Of New York Mellon Corp | Institution | 742,758 | Added More | 110,963 | 17.56 % | $11,906,411 | $9,997,523 | $-1,908,888 | -16.03 % | $-285,175 | | | | | | News Article | History of Bank Of New York Mellon Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Barclays Plc | Institution | 121,783 | Sold Some | -3,120 | -2.49 % | $1,952,181 | $1,639,199 | $-312,982 | -16.03 % | $8,018 | | | | | | News Article | History of Barclays Plc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Federated Investors Inc | Institution | 7,631,777 | Sold Some | -15,136 | -0.19 % | $122,337,385 | $102,723,718 | $-19,613,667 | -16.03 % | $38,900 | | | | | | News Article | History of Federated Investors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Fortis Investments Management Usa Inc | Institution | 53,317 | Sold Some | -70,209 | -56.83 % | $854,672 | $717,647 | $-137,025 | -16.03 % | $180,437 | | | | | | News Article | History of Fortis Investments Management Usa Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Ing Investment Management Co | Institution | 87,200 | Sold Some | -86,000 | -49.65 % | $1,397,816 | $1,173,712 | $-224,104 | -16.03 % | $221,020 | | | | | | News Article | History of Ing Investment Management Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR/A | Ironbridge Capital Management Llc | Institution | 1,046,581 | Sold Some | -16,191 | -1.52 % | $16,776,693 | $14,086,980 | $-2,689,713 | -16.03 % | $41,611 | | | | | | News Article | History of Ironbridge Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | J P Morgan Chase And Co | Institution | 387,789 | Added More | 352,930 | 1012.45 % | $6,216,258 | $5,219,640 | $-996,618 | -16.03 % | $-907,030 | | | | | | News Article | History of J P Morgan Chase And Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Renaissance Technologies Corp | Institution | 10,600 | Sold Some | -12,014 | -53.12 % | $169,918 | $142,676 | $-27,242 | -16.03 % | $30,876 | | | | | | News Article | History of Renaissance Technologies Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Ubs Ag | Institution | 49,346 | Added More | 633 | 1.29 % | $791,016 | $664,197 | $-126,819 | -16.03 % | $-1,627 | | | | | | News Article | History of Ubs Ag Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Untrust Banks Inc | Institution | 184,809 | Sold Some | -2,448 | -1.30 % | $2,962,488 | $2,487,529 | $-474,959 | -16.03 % | $6,291 | | | | | | News Article | History of Untrust Banks Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Wells Fargo And Co | Institution | 505,056 | Sold Some | -18,807 | -3.59 % | $8,096,048 | $6,798,054 | $-1,297,994 | -16.03 % | $48,334 | | | | | | News Article | History of Wells Fargo And Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Wexford Capital Llc | Institution | | Sold All | -38,423 | -100 % | | | | -16.03 % | $98,747 | | | | | | News Article | History of Wexford Capital Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | William Harris Investors Inc | Institution | 611,134 | Sold Some | -20,000 | -3.16 % | $9,796,478 | $8,225,864 | $-1,570,614 | -16.03 % | $51,400 | | | | | | News Article | History of William Harris Investors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-13 | 2009-06-30 | 13F-HR | Zacks Investment Management | Institution | | Sold All | -41,729 | -100 % | | | | -16.03 % | $107,244 | | | | | | News Article | History of Zacks Investment Management Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Allianz Global Investors Of America L P | Institution | 391,939 | Sold Some | -686 | -0.17 % | $6,184,797 | $5,275,499 | $-909,298 | -14.70 % | $1,592 | | | | | | News Article | History of Allianz Global Investors Of America L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Cadence Capital Management Llc | Institution | 346,230 | New Holding | 346,230 | 100 % | $5,463,509 | $4,660,256 | $-803,254 | -14.70 % | $-803,254 | | | | | | News Article | History of Cadence Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR/A | Cookson Peirce And Co Inc | Institution | 304,551 | Sold Some | -11,795 | -3.72 % | $4,805,815 | $4,099,256 | $-706,558 | -14.70 % | $27,364 | | | | | | News Article | History of Cookson Peirce And Co Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Credit Suisse First Boston | Institution | 138,258 | Added More | 60,896 | 78.71 % | $2,181,711 | $1,860,953 | $-320,759 | -14.70 % | $-141,279 | | | | | | News Article | History of Credit Suisse First Boston Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Dafna Capital Management Llc | Institution | 689,477 | Sold Some | -128,100 | -15.66 % | $10,879,947 | $9,280,360 | $-1,599,587 | -14.70 % | $297,192 | | | | | | News Article | History of Dafna Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | First Quadrant L P | Institution | 23,400 | No Change | 0 | 0 % | $369,252 | $314,964 | $-54,288 | -14.70 % | $0 | | | | | | News Article | History of First Quadrant L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Fortaleza Asset Management Inc | Institution | 68,420 | Sold Some | -43,675 | -38.96 % | $1,079,668 | $920,933 | $-158,734 | -14.70 % | $101,326 | | | | | | News Article | History of Fortaleza Asset Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Franklin Resources Inc | Institution | 358,013 | Added More | 229,703 | 179.02 % | $5,649,445 | $4,818,855 | $-830,590 | -14.70 % | $-532,911 | | | | | | News Article | History of Franklin Resources Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Ghp Investment Advisors Inc | Institution | 250 | New Holding | 250 | 100 % | $3,945 | $3,365 | $-580 | -14.70 % | $-580 | | | | | | News Article | History of Ghp Investment Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Lee Munder Investments Ltd | Institution | 100,333 | Added More | 11,191 | 12.55 % | $1,583,255 | $1,350,482 | $-232,773 | -14.70 % | $-25,963 | | | | | | News Article | History of Lee Munder Investments Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Rbc Asset Management Inc | Institution | | Sold All | -3,900 | -100 % | | | | -14.70 % | $9,048 | | | | | | News Article | History of Rbc Asset Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Stafford Asset Management Llc | No Data | | Sold All | -14,925 | -100 % | | | | -14.70 % | $34,626 | | | | | | News Article | History of Stafford Asset Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Usquehanna International Group Llp | Institution | 30,287 | Sold Some | -22,188 | -42.28 % | $477,929 | $407,663 | $-70,266 | -14.70 % | $51,476 | | | | | | News Article | History of Usquehanna International Group Llp Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | Virginia Retirement Systems Et Al | Institution | 38,100 | No Change | 0 | 0 % | $601,218 | $512,826 | $-88,392 | -14.70 % | $0 | | | | | | News Article | History of Virginia Retirement Systems Et Al Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-12 | 2009-06-30 | 13F-HR | World Asset Management Inc | Institution | 11,845 | No Change | 0 | 0 % | $186,914 | $159,434 | $-27,480 | -14.70 % | $0 | | | | | | News Article | History of World Asset Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | American Century Companies Inc | Institution | 324,655 | Sold Some | -29,265 | -8.26 % | $5,152,275 | $4,369,856 | $-782,419 | -15.18 % | $70,529 | | | | | | News Article | History of American Century Companies Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Amvescap Plc | Institution | 961,547 | Sold Some | -378,257 | -28.23 % | $15,259,751 | $12,942,423 | $-2,317,328 | -15.18 % | $911,599 | | | | | | News Article | History of Amvescap Plc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Blackrock Inc | No Data | 28,967 | New Holding | 28,967 | 100 % | $459,706 | $389,896 | $-69,810 | -15.18 % | $-69,810 | | | | | | News Article | History of Blackrock Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Chilton Capital Management Advisors Inc | Institution | 67,590 | Sold Some | -23,380 | -25.70 % | $1,072,653 | $909,761 | $-162,892 | -15.18 % | $56,346 | | | | | | News Article | History of Chilton Capital Management Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Chilton Capital Management L P | Institution | 124,595 | Sold Some | -67,226 | -35.04 % | $1,977,323 | $1,677,049 | $-300,274 | -15.18 % | $162,015 | | | | | | News Article | History of Chilton Capital Management L P Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Cumberland Associates Llc | Institution | 210,000 | Sold Some | -490,000 | -70.00 % | $3,332,700 | $2,826,600 | $-506,100 | -15.18 % | $1,180,900 | | | | | | News Article | History of Cumberland Associates Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Ectoral Asset Management Inc | Institution | 2,474,188 | Added More | 307,500 | 14.19 % | $39,265,364 | $33,302,570 | $-5,962,793 | -15.18 % | $-741,075 | | | | | | News Article | History of Ectoral Asset Management Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | First National Trust Co | Institution | | Sold All | -1,394 | -100 % | | | | -15.18 % | $3,360 | | | | | | News Article | History of First National Trust Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Johnston Asset Management Corp | Institution | 800,276 | Added More | 16,470 | 2.10 % | $12,700,380 | $10,771,715 | $-1,928,665 | -15.18 % | $-39,693 | | | | | | News Article | History of Johnston Asset Management Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Neuberger Berman Group Llc | No Data | 18,773 | No Compare | | | $297,928 | $252,685 | $-45,243 | -15.18 % | | | | | | | News Article | History of Neuberger Berman Group Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Old Mutual Asset Managers Uk Ltd | Institution | 118,028 | New Holding | 118,028 | 100 % | $1,873,104 | $1,588,657 | $-284,447 | -15.18 % | $-284,447 | | | | | | News Article | History of Old Mutual Asset Managers Uk Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Padco Advisors Ii Inc | Institution | 20,868 | Sold Some | -14,604 | -41.17 % | $331,175 | $280,883 | $-50,292 | -15.18 % | $35,196 | | | | | | News Article | History of Padco Advisors Ii Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Padco Advisors Inc | Institution | 119,263 | Added More | 9,069 | 8.23 % | $1,892,704 | $1,605,280 | $-287,424 | -15.18 % | $-21,856 | | | | | | News Article | History of Padco Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Ubs Global Asset Management Americas Inc | Institution | 504,000 | Sold Some | -250,153 | -33.17 % | $7,998,480 | $6,783,840 | $-1,214,640 | -15.18 % | $602,869 | | | | | | News Article | History of Ubs Global Asset Management Americas Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-11 | 2009-06-30 | 13F-HR | Ymphony Asset Management Llc | Institution | 352,292 | Added More | 131,290 | 59.40 % | $5,590,874 | $4,741,850 | $-849,024 | -15.18 % | $-316,409 | | | | | | News Article | History of Ymphony Asset Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR | Chicago Equity Partners Llc | Institution | 27,650 | New Holding | 27,650 | 100 % | $455,672 | $372,169 | $-83,503 | -18.32 % | $-83,503 | | | | | | News Article | History of Chicago Equity Partners Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR | Comerica Bank | Institution | 59,077 | Added More | 29,638 | 100.67 % | $973,589 | $795,176 | $-178,413 | -18.32 % | $-89,507 | | | | | | News Article | History of Comerica Bank Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR | Davenport And Co Llc | Institution | 1,202,025 | Added More | 104,043 | 9.47 % | $19,809,372 | $16,179,257 | $-3,630,116 | -18.32 % | $-314,210 | | | | | | News Article | History of Davenport And Co Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR | Dimensional Fund Advisors Inc | Institution | 713,468 | Sold Some | -15,961 | -2.18 % | $11,757,953 | $9,603,279 | $-2,154,673 | -18.32 % | $48,202 | | | | | | News Article | History of Dimensional Fund Advisors Inc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR | G Americas Securities Llc | Institution | | Sold All | -14,730 | -100 % | | | | -18.32 % | $44,485 | | | | | | News Article | History of G Americas Securities Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR/A | Green Square Capital Management Llc | Institution | 20,100 | No Change | 0 | 0 % | $331,248 | $270,546 | $-60,702 | -18.32 % | $0 | | | | | | News Article | History of Green Square Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR | Hartford Investment Management Co | Institution | 253,526 | Added More | 56,825 | 28.88 % | $4,178,108 | $3,412,460 | $-765,649 | -18.32 % | $-171,612 | | | | | | News Article | History of Hartford Investment Management Co Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR | Lazard Asset Management Llc | Institution | | Sold All | -25,000 | -100 % | | | | -18.32 % | $75,500 | | | | | | News Article | History of Lazard Asset Management Llc Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR | Mfc Global Investment Management Usa Ltd | Institution | 83,920 | Sold Some | -12,560 | -13.01 % | $1,383,002 | $1,129,563 | $-253,438 | -18.32 % | $37,931 | | | | | | News Article | History of Mfc Global Investment Management Usa Ltd Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR | Overeign Asset Management Corp | Institution | 116,225 | Sold Some | -35,454 | -23.37 % | $1,915,388 | $1,564,389 | $-351,000 | -18.32 % | $107,071 | | | | | | News Article | History of Overeign Asset Management Corp Ownership Of Isis Pharmaceuticals Inc |
| 2009-08-10 | 2009-06-30 | 13F-HR | Uffolk Capital Management Llc | Institution | 45,000 | Sold Some | -16,000 | -26.22 % | $741,600 | $605,700 | $-135,900 | -18.32 % | $48,320 | | | | | | News Article | History of Uffolk Capital Management Llc Ownership Of Isis Pharmaceuticals Inc |
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