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Last Activity: 2010-03-11

Country: United States

Industry: Chemicals-Specialty

Transactions: Currently showing holdings/transactions Filed between 2009-12-11 and 2010-03-11

Prices: Currenty using base stock prices on Filing Date compared to stock prices on 2010-03-16

Hypotheticals

Hypotheticals use the owners holdings and changes reported as a model portfolio combining with stock price changes between the base price date and end price date. All results/returns are hypothetical and are not actual results!

Contact Information

3100 Central Expressway,Santa Clara, Ca 95051,,United States Phone: 408-764-2000 Fax: 408-748-0745 Website: HTTP://WWW.SYMYX.COM

ISIN International Securities Identification Number

US87155S1087

CUSIP Committee on Uniform Securities Identification Procedures

87155S108

Stock Symbols and Exchanges
Exchange Symbol	Reuters	Bloomberg	Exchange Name	MICR	ACCR	City	Country	Website
smmx	smmx	smmx:us	Nasdaq	xnas	nasdaq	New York	United States	WWW.NASDAQ.COM

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Owners Summary
Owners:	163	Owners Buying:	58	Buying Pct.:	35.58 %	Owners Netrual:	28	Neutral Pct.:	17.17 %	Owners Selling:	73	Selling Pct.:	44.78 %
Score:	2.78	Brand New:	18	Increase Existing:	40	No Change:	28	Sold Some:	47	Dumped All:	26	No Comparison:	4

Owners Reporting Options
Use 'As-Of/On' instead of 'Filed' for dates:		Begin date:		End date:
A begin price of 1900-01-01 will use the date filed for begin price:		Begin Price date:		End Price date:
- report date span limited to 100 days, all dates in format of yyyy-mm-dd, all fields required!

Show/Hide Columns
Filed	As Of/On	Form	Name
Fundclass	Shares	Activity	Shares Change
Shares Change Pct.	Hypothetical Old Value	Hypothetical New Value	Hypothetical Value Change
Hypothetical Return	Hypothetical Results	Director	Ten Pct
Other	Officer	Officer Title	History

Holdings/Transactions

Filed	As-Of/On	Form	Fullname	Fund Class	Shares	Activity	Shares Change	Shares Pct. Change	Hypothetical Old Value	Hypothetical New Value	Hypothetical Value Chg.	Hypotheticals Return	Hypotheticals Results	Director	Other	Ten Pct	Officer	Officer Title	History
2010-03-11	2009-12-31	N-CSR	Advanced Series Trust - Ast Global Allocation Portfolio	Global Flex Port		Sold All	-33,200	-100 %				2.89 %	$-4,316						History of Advanced Series Trust - Ast Global Allocation Portfolio Ownership Of Symyx Technologies
2010-03-11	2009-12-31	N-CSR	Advanced Series Trust - Ast Western Asset Core Plus Bond Portfolio	No Data		Sold All	-11,300	-100 %				2.89 %	$-1,469						History of Advanced Series Trust - Ast Western Asset Core Plus Bond Portfolio Ownership Of Symyx Technologies
2010-03-11	2009-12-31	N-CSR	Wilshire Mutual Funds Inc - Wilshire Small Company Growth Portfolio	Small-Cap Growth	300	No Change	0	0 %	$1,347	$1,386	$39	2.89 %	$0						History of Wilshire Mutual Funds Inc - Wilshire Small Company Growth Portfolio Ownership Of Symyx Technologies
2010-03-11	2009-12-31	N-CSR	Wilshire Mutual Funds Inc - Wilshire Small Company Value Portfolio	Small-Cap Value	324	Sold Some	-100	-23.58 %	$1,455	$1,497	$42	2.89 %	$-13						History of Wilshire Mutual Funds Inc - Wilshire Small Company Value Portfolio Ownership Of Symyx Technologies
2010-03-10	2009-12-31	N-CSR	Jnl Series Trust - Jnlmcm Small Cap Index Fund A	Small-Cap Core	16	No Compare			$72	$74	$2	2.43 %							History of Jnl Series Trust - Jnlmcm Small Cap Index Fund A Ownership Of Symyx Technologies
2010-03-10	2009-12-31	N-CSR	Rydex Dynamic Funds - Dow 2x Strategy Master Fund	Specialty & Misc	676	New Holding	676	100 %	$3,049	$3,123	$74	2.43 %	$74						History of Rydex Dynamic Funds - Dow 2x Strategy Master Fund Ownership Of Symyx Technologies
2010-03-10	2009-12-31	N-CSR	Rydex Series Funds - Banking Fund	Financial Services	588	Sold Some	-160	-21.39 %	$2,652	$2,717	$65	2.43 %	$-18						History of Rydex Series Funds - Banking Fund Ownership Of Symyx Technologies
2010-03-10	2009-12-31	N-CSR	Rydex Variable Trust - Biotechnology Fund	Health/Biotech	368	Sold Some	-12	-3.15 %	$1,660	$1,700	$40	2.43 %	$-1						History of Rydex Variable Trust - Biotechnology Fund Ownership Of Symyx Technologies
2010-03-09	2009-12-31	N-CSR	Pacific Select Fund - Pd Small-Cap Growth Index Portfolio	No Data	606	Added More	51	9.18 %	$2,769	$2,800	$30	1.09 %	$3						History of Pacific Select Fund - Pd Small-Cap Growth Index Portfolio Ownership Of Symyx Technologies
2010-03-09	2009-12-31	N-CSR	Pacific Select Fund - Pd Small-Cap Value Index Portfolio	No Data	186	Added More	34	22.36 %	$850	$859	$9	1.09 %	$2						History of Pacific Select Fund - Pd Small-Cap Value Index Portfolio Ownership Of Symyx Technologies
2010-03-09	2009-12-31	N-CSR	Pacific Select Fund - Small-Cap Index Portfolio	No Data	17,447	Sold Some	-600	-3.32 %	$79,733	$80,605	$872	1.09 %	$-30						History of Pacific Select Fund - Small-Cap Index Portfolio Ownership Of Symyx Technologies
2010-03-09	2009-12-31	N-CSR	Summit Mutual Funds Inc - Zenith Portfolio	Specialty & Misc	2,680	New Holding	2,680	100 %	$12,248	$12,382	$134	1.09 %	$134						History of Summit Mutual Funds Inc - Zenith Portfolio Ownership Of Symyx Technologies
2010-03-08	2009-12-31	N-CSR	Massmutual Select Funds - Massmutual Select Small Company Value Fund	Small-Cap Core	84,700	Sold Some	-1,200	-1.39 %	$381,997	$391,314	$9,317	2.43 %	$-132						History of Massmutual Select Funds - Massmutual Select Small Company Value Fund Ownership Of Symyx Technologies
2010-03-08	2009-12-31	N-CSR	Mml Series Investment Fund - Mml Small Company Value Fund	No Data	35,500	No Change	0	0 %	$160,105	$164,010	$3,905	2.43 %	$0						History of Mml Series Investment Fund - Mml Small Company Value Fund Ownership Of Symyx Technologies
2010-03-08	2009-12-31	N-CSR	Profunds - Bull Profund	Large-Cap Core	1,080	Sold Some	-1,480	-57.81 %	$4,871	$4,990	$119	2.43 %	$-163						History of Profunds - Bull Profund Ownership Of Symyx Technologies
2010-03-05	2009-12-31	N-CSR	Axa Premier Vip Trust - Axa Aggressive Allocation Portfolio	Specialty & Misc	1,400	No Compare			$6,314	$6,468	$154	2.43 %							History of Axa Premier Vip Trust - Axa Aggressive Allocation Portfolio Ownership Of Symyx Technologies
2010-03-05	2009-12-31	N-CSR	Axa Premier Vip Trust - Multimanager Small Cap Growth Portfolio	Small-Cap Growth	26,500	Added More	4,400	19.90 %	$119,515	$122,430	$2,915	2.43 %	$484						History of Axa Premier Vip Trust - Multimanager Small Cap Growth Portfolio Ownership Of Symyx Technologies
2010-03-05	2009-12-31	N-CSR	Axa Premier Vip Trust - Multimanager Small Cap Value Portfolio	Small-Cap Value	8,900	No Change	0	0 %	$40,139	$41,118	$979	2.43 %	$0						History of Axa Premier Vip Trust - Multimanager Small Cap Value Portfolio Ownership Of Symyx Technologies
2010-03-05	2009-12-31	13F-HR/A	Royce And Associates Llc	Institution	3,865,700	No Change	0	0 %	$17,434,307	$17,859,534	$425,227	2.43 %	$0						History of Royce And Associates Llc Ownership Of Symyx Technologies
2010-03-04	2009-12-31	N-CSR	Ancora Trust - Ancora Microcap Fund	No Data	8,000	Added More	5,000	166.66 %	$34,320	$36,960	$2,640	7.69 %	$1,650						History of Ancora Trust - Ancora Microcap Fund Ownership Of Symyx Technologies
2010-03-04	2009-12-31	N-CSR	Direxion Insurance Trust - Dynamic Vp Hy Bond Fund	Specialty & Misc		Sold All	-4,613	-100 %				7.69 %	$-1,522						History of Direxion Insurance Trust - Dynamic Vp Hy Bond Fund Ownership Of Symyx Technologies
2010-03-04	2009-12-31	N-CSR	Eq Advisors Trust - Eqalliancebernstein Small Cap Growth Portfolio	Small-Cap Growth	25,200	No Change	0	0 %	$108,108	$116,424	$8,316	7.69 %	$0						History of Eq Advisors Trust - Eqalliancebernstein Small Cap Growth Portfolio Ownership Of Symyx Technologies
2010-03-04	2009-12-31	N-CSR	Eq Advisors Trust - Eqalliancebernstein Value Portfolio	Multi-Cap Value	6,050	No Change	0	0 %	$25,955	$27,951	$1,997	7.69 %	$0						History of Eq Advisors Trust - Eqalliancebernstein Value Portfolio Ownership Of Symyx Technologies
2010-03-04	2009-12-31	N-CSR	Eq Advisors Trust - Eqbond Index Portfolio	Specialty & Misc	470	Sold Some	-35,816	-98.70 %	$2,016	$2,171	$155	7.69 %	$-11,819						History of Eq Advisors Trust - Eqbond Index Portfolio Ownership Of Symyx Technologies
2010-03-04	2009-12-31	N-CSR	Eq Advisors Trust - Eqmutual Shares Portfolio	Specialty & Misc	26,408	New Holding	26,408	100 %	$113,290	$122,005	$8,715	7.69 %	$8,715						History of Eq Advisors Trust - Eqmutual Shares Portfolio Ownership Of Symyx Technologies
2010-03-04	2009-12-31	N-CSRS	Streettracks Series Trust - Spdr Dividend Etf	Specialty & Misc		Sold All	-5,317	-100 %				7.69 %	$-1,755						History of Streettracks Series Trust - Spdr Dividend Etf Ownership Of Symyx Technologies
2010-03-04	2009-12-31	N-CSR	Vanguard Balanced Index Funds - Vanguard Balanced Index Fund	Mixed-Asset Target Allocation Growth	22,358	New Holding	22,358	100 %	$95,916	$103,294	$7,378	7.69 %	$7,378						History of Vanguard Balanced Index Funds - Vanguard Balanced Index Fund Ownership Of Symyx Technologies
2010-03-03	2009-12-31	N-CSR	Tiaa Cref Life Fund - Stock Index Fund	Specialty & Misc	299	No Change	0	0 %	$1,277	$1,381	$105	8.19 %	$0						History of Tiaa Cref Life Fund - Stock Index Fund Ownership Of Symyx Technologies
2010-03-03	2009-12-31	N-CSR	Tiaa Separate Account Va 1 - Stock Index Account	Specialty & Misc		Sold All	-1,956	-100 %				8.19 %	$-685						History of Tiaa Separate Account Va 1 - Stock Index Account Ownership Of Symyx Technologies
2010-03-03	2009-12-31	13F-HR/A	Vanguard Group Inc	Institution	1,606,518	Added More	98,699	6.54 %	$6,859,832	$7,422,113	$562,281	8.19 %	$34,545						History of Vanguard Group Inc Ownership Of Symyx Technologies
2010-03-03	2009-12-31	N-CSR	Vanguard Index Funds - Vanguard 500 Index Fund	S&P 500 Index		Sold All	-281,986	-100 %				8.19 %	$-98,695						History of Vanguard Index Funds - Vanguard 500 Index Fund Ownership Of Symyx Technologies
2010-03-03	2009-12-31	N-CSR	Vanguard Institutional Index Funds - Vanguard Institutional Index Fund	Specialty & Misc	11,194	Added More	819	7.89 %	$47,798	$51,716	$3,918	8.19 %	$287						History of Vanguard Institutional Index Funds - Vanguard Institutional Index Fund Ownership Of Symyx Technologies
2010-03-02	2009-12-31	N-Q/A	Assetmark Funds - Assetmark Fundamental Index Small Company Growth Fund	Small-Cap Growth	1,044	New Holding	1,044	100 %	$4,614	$4,823	$209	4.52 %	$209						History of Assetmark Funds - Assetmark Fundamental Index Small Company Growth Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Ge Funds - Ge Value Equity Fund	Large-Cap Core	7,800	Sold Some	-800	-9.30 %	$34,710	$36,036	$1,326	3.82 %	$-136						History of Ge Funds - Ge Value Equity Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Ge Institutional Funds - Income Fund	Equity Income	131,400	No Change	0	0 %	$584,730	$607,068	$22,338	3.82 %	$0						History of Ge Institutional Funds - Income Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Ge Institutional Funds - Premier Growth Equity Fund	Multi-Cap Growth		Sold All	-112,900	-100 %				3.82 %	$-19,193						History of Ge Institutional Funds - Premier Growth Equity Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Ishares Trust - Ishares Russell 2000 Growth Index Fund	Multi-Cap Growth	196,561	Sold Some	-5,620	-2.77 %	$874,696	$908,112	$33,415	3.82 %	$-955						History of Ishares Trust - Ishares Russell 2000 Growth Index Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Ishares Trust - Ishares Russell 2000 Index Fund	Specialty & Misc	473,983	Sold Some	-13,806	-2.83 %	$2,109,224	$2,189,801	$80,577	3.82 %	$-2,347						History of Ishares Trust - Ishares Russell 2000 Index Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Ishares Trust - Ishares Russell 2000 Value Index Fund	Multi-Cap Value	51,280	Sold Some	-9,900	-16.18 %	$228,196	$236,914	$8,718	3.82 %	$-1,683						History of Ishares Trust - Ishares Russell 2000 Value Index Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Ishares Trust - Ishares Russell 3000 Growth Index Fund	Multi-Cap Growth	1,608	Sold Some	-90	-5.30 %	$7,156	$7,429	$273	3.82 %	$-15						History of Ishares Trust - Ishares Russell 3000 Growth Index Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Ishares Trust - Ishares Russell 3000 Index Fund	Specialty & Misc	7,784	Sold Some	-504	-6.08 %	$34,639	$35,962	$1,323	3.82 %	$-86						History of Ishares Trust - Ishares Russell 3000 Index Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Ishares Trust - Ishares Russell 3000 Value Index Fund	Multi-Cap Value	334	Sold Some	-33	-8.99 %	$1,486	$1,543	$57	3.82 %	$-6						History of Ishares Trust - Ishares Russell 3000 Value Index Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Ishares Trust - Ishares Russell Microcap Index Fund	Specialty & Misc	50,936	Sold Some	-5,352	-9.50 %	$226,665	$235,324	$8,659	3.82 %	$-910						History of Ishares Trust - Ishares Russell Microcap Index Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Rydex Series Funds - Russell 2000 Fund	Specialty & Misc	360	New Holding	360	100 %	$1,602	$1,663	$61	3.82 %	$61						History of Rydex Series Funds - Russell 2000 Fund Ownership Of Symyx Technologies
2010-03-01	2009-12-31	N-Q	Tiaa Cref Institutional Mutual Funds - Equity Index Fund	Specialty & Misc	23,056	No Change	0	0 %	$102,599	$106,519	$3,920	3.82 %	$0						History of Tiaa Cref Institutional Mutual Funds - Equity Index Fund Ownership Of Symyx Technologies
2010-02-26	2009-12-31	N-Q	Usaa Mutual Funds Trust - Growth Fund	Multi-Cap Growth		Sold All	-700	-100 %				5.96 %	$-182						History of Usaa Mutual Funds Trust - Growth Fund Ownership Of Symyx Technologies
2010-02-25	2009-12-31	N-Q	Lotsoff Capital Management Investment Trust - Lotsoff Capital Management Micro Cap Fund	Specialty & Misc	12,400	New Holding	12,400	100 %	$54,932	$57,288	$2,356	4.28 %	$2,356						History of Lotsoff Capital Management Investment Trust - Lotsoff Capital Management Micro Cap Fund Ownership Of Symyx Technologies
2010-02-25	2009-12-31	13F-HR/A	Northern Trust Corp	Institution	687,015	Added More	5,544	0.81 %	$3,043,476	$3,174,009	$130,533	4.28 %	$1,053						History of Northern Trust Corp Ownership Of Symyx Technologies
2010-02-18	2009-12-31	13F-HR/A	American International Group Inc	Institution	27,836	Added More	245	0.88 %	$128,046	$128,602	$557	0.43 %	$5						History of American International Group Inc Ownership Of Symyx Technologies
2010-02-17	2009-12-31	13F-HR	Barclays Plc	Institution	24,297	Added More	14,083	137.87 %	$112,009	$112,252	$243	0.21 %	$141						History of Barclays Plc Ownership Of Symyx Technologies
2010-02-17	2009-12-31	13F-HR/A	Credit Suisse	Institution		Sold All	-100	-100 %				0.21 %	$-1						History of Credit Suisse Ownership Of Symyx Technologies
2010-02-17	2009-12-31	13F-HR	Us Bancorp De	Institution	2,447	No Change	0	0 %	$11,281	$11,305	$24	0.21 %	$0						History of Us Bancorp De Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Amvescap Plc	Institution	631,835	Added More	61,875	10.85 %	$2,906,441	$2,919,078	$12,637	0.43 %	$1,238						History of Amvescap Plc Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Ancora Advisors Llc	Institution	31,300	Sold Some	-23,000	-42.35 %	$143,980	$144,606	$626	0.43 %	$-460						History of Ancora Advisors Llc Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Bogle Investment Management L P	Institution	39,449	Sold Some	-1,855	-4.49 %	$181,465	$182,254	$789	0.43 %	$-37						History of Bogle Investment Management L P Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Brown Investment Advisory And Trust Co	Institution		Sold All	-18,100	-100 %				0.43 %	$-362						History of Brown Investment Advisory And Trust Co Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Conus Partners Inc	Institution	1,647,595	Added More	394,287	31.45 %	$7,578,937	$7,611,889	$32,952	0.43 %	$7,886						History of Conus Partners Inc Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Credit Suisse First Boston	Institution	70,507	Added More	59,668	550.49 %	$324,332	$325,742	$1,410	0.43 %	$1,193						History of Credit Suisse First Boston Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Forward Management Llc	Institution	35,772	Sold Some	-2,763	-7.17 %	$164,551	$165,267	$715	0.43 %	$-55						History of Forward Management Llc Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Goldman Sachs Group Inc	Institution	891,734	Sold Some	-632,788	-41.50 %	$4,101,976	$4,119,811	$17,835	0.43 %	$-12,656						History of Goldman Sachs Group Inc Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Ing Groep Nv	Institution	24,920	Added More	10,250	69.87 %	$114,632	$115,130	$498	0.43 %	$205						History of Ing Groep Nv Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Mfc Global Investment Management Usa Ltd	Institution	37,405	Added More	1,951	5.50 %	$172,063	$172,811	$748	0.43 %	$39						History of Mfc Global Investment Management Usa Ltd Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Morgan Stanley	Institution	35,453	Sold Some	-13,491	-27.56 %	$163,084	$163,793	$709	0.43 %	$-270						History of Morgan Stanley Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Principal Financial Group Inc	Institution	16,507	New Holding	16,507	100 %	$75,932	$76,262	$330	0.43 %	$330						History of Principal Financial Group Inc Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Prudential Financial Inc	Institution	35,700	Added More	7,100	24.82 %	$164,220	$164,934	$714	0.43 %	$142						History of Prudential Financial Inc Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Shaw D E And Co Inc	Institution	63,639	New Holding	63,639	100 %	$292,739	$294,012	$1,273	0.43 %	$1,273						History of Shaw D E And Co Inc Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Two Sigma Investments Llc	Institution	16,300	New Holding	16,300	100 %	$74,980	$75,306	$326	0.43 %	$326						History of Two Sigma Investments Llc Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Ubs Ag	Institution	65,439	Added More	12,225	22.97 %	$301,019	$302,328	$1,309	0.43 %	$245						History of Ubs Ag Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Wells Fargo And Co	Institution	2,972,168	Added More	76,600	2.64 %	$13,671,973	$13,731,416	$59,443	0.43 %	$1,532						History of Wells Fargo And Co Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Wexford Capital Llc	Institution	43,700	New Holding	43,700	100 %	$201,020	$201,894	$874	0.43 %	$874						History of Wexford Capital Llc Ownership Of Symyx Technologies
2010-02-16	2009-12-31	13F-HR	Zebra Capital Management Llc	Institution	8,934	Added More	8,330	1379.13 %	$41,096	$41,275	$179	0.43 %	$167						History of Zebra Capital Management Llc Ownership Of Symyx Technologies
2010-02-16	2009-09-30	13F-HR/A	Ubs Ag	Institution	53,214	Added More	4,488	9.21 %	$244,784	$245,849	$1,064	0.43 %	$90						History of Ubs Ag Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Algert Coldiron Investors Llc	Institution	22,909	Added More	2,600	12.80 %	$108,818	$105,840	$-2,978	-2.73 %	$-338						History of Algert Coldiron Investors Llc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Ameriprise Financial Inc	Institution	2,000	No Change	0	0 %	$9,500	$9,240	$-260	-2.73 %	$0						History of Ameriprise Financial Inc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Axa	Institution	89,121	Sold Some	-19,016	-17.58 %	$423,325	$411,739	$-11,586	-2.73 %	$2,472						History of Axa Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Barclays Global Investors Na Ca	Institution	1,230,823	Added More	168,301	15.83 %	$5,846,409	$5,686,402	$-160,007	-2.73 %	$-21,879						History of Barclays Global Investors Na Ca Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Blackrock Fund Advisors	No Data	789,914	No Compare			$3,752,092	$3,649,403	$-102,689	-2.73 %							History of Blackrock Fund Advisors Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Blackrock Group Ltd	Institution	3,448	Sold Some	-5,900	-63.11 %	$16,378	$15,930	$-448	-2.73 %	$767						History of Blackrock Group Ltd Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Blackrock Investment Management Llc	Institution	94,831	Sold Some	-11,057	-10.44 %	$450,447	$438,119	$-12,328	-2.73 %	$1,437						History of Blackrock Investment Management Llc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Falcon Investment Management Llc	Institution		Sold All	-73,747	-100 %				-2.73 %	$9,587						History of Falcon Investment Management Llc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Geode Capital Management Llc	Institution	73,100	No Change	0	0 %	$347,225	$337,722	$-9,503	-2.73 %	$0						History of Geode Capital Management Llc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Jacobs Levy Equity Management Inc	Institution	109,900	Sold Some	-2,600	-2.31 %	$522,025	$507,738	$-14,287	-2.73 %	$338						History of Jacobs Levy Equity Management Inc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Liberty Mutual Insurance Co	Institution	23,100	No Change	0	0 %	$109,725	$106,722	$-3,003	-2.73 %	$0						History of Liberty Mutual Insurance Co Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Madison Square Investors Llc	No Data	62,358	Added More	39,661	174.74 %	$296,201	$288,094	$-8,107	-2.73 %	$-5,156						History of Madison Square Investors Llc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Mason Street Advisors Llc	Institution	113,400	No Change	0	0 %	$538,650	$523,908	$-14,742	-2.73 %	$0						History of Mason Street Advisors Llc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Nomura Holdings Inc	Institution	16,025	New Holding	16,025	100 %	$76,119	$74,036	$-2,083	-2.73 %	$-2,083						History of Nomura Holdings Inc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Oppenheimer And Co Inc	Institution	38,432	Sold Some	-3,334	-7.98 %	$182,552	$177,556	$-4,996	-2.73 %	$433						History of Oppenheimer And Co Inc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Oppenheimer Funds Inc	Institution	12,100	Sold Some	-8,300	-40.68 %	$57,475	$55,902	$-1,573	-2.73 %	$1,079						History of Oppenheimer Funds Inc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Pergamon Offshore Advisors L P	Institution		Sold All	-103,737	-100 %				-2.73 %	$13,486						History of Pergamon Offshore Advisors L P Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Price T Rowe Associates Inc	Institution	2,353,713	Sold Some	-456,988	-16.25 %	$11,180,137	$10,874,154	$-305,983	-2.73 %	$59,408						History of Price T Rowe Associates Inc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Renaissance Technologies Corp	Institution	663,576	Added More	52,261	8.54 %	$3,151,986	$3,065,721	$-86,265	-2.73 %	$-6,794						History of Renaissance Technologies Corp Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Schwab Charles Investment Management Inc	Institution	9,410	Sold Some	-2,600	-21.64 %	$44,698	$43,474	$-1,223	-2.73 %	$338						History of Schwab Charles Investment Management Inc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Spark Lp	Institution	15,200	Sold Some	-5,500	-26.57 %	$72,200	$70,224	$-1,976	-2.73 %	$715						History of Spark Lp Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Stafford Asset Management Llc	No Data	17,550	New Holding	17,550	100 %	$83,363	$81,081	$-2,282	-2.73 %	$-2,282						History of Stafford Asset Management Llc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Technical Financial Services Llc	Institution		Sold All	-18,022	-100 %				-2.73 %	$2,343						History of Technical Financial Services Llc Ownership Of Symyx Technologies
2010-02-12	2009-12-31	13F-HR	Wellington Management Co Llp	Institution	420,444	Sold Some	-3,800	-0.89 %	$1,997,109	$1,942,451	$-54,658	-2.73 %	$494						History of Wellington Management Co Llp Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	American Century Companies Inc	Institution	16,855	Sold Some	-5,102	-23.23 %	$85,792	$77,870	$-7,922	-9.23 %	$2,398						History of American Century Companies Inc Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Bank Of America Corp	Institution	5,507	Sold Some	-21,253	-79.42 %	$28,031	$25,442	$-2,588	-9.23 %	$9,989						History of Bank Of America Corp Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Highbridge Capital Management Llc	Institution		Sold All	-38,813	-100 %				-9.23 %	$18,242						History of Highbridge Capital Management Llc Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Ing Investment Management Co	Institution	24,920	Added More	10,250	69.87 %	$126,843	$115,130	$-11,712	-9.23 %	$-4,818						History of Ing Investment Management Co Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Metropolitan Life Insurance Co	Institution	34,519	Added More	2,986	9.46 %	$175,702	$159,478	$-16,224	-9.23 %	$-1,403						History of Metropolitan Life Insurance Co Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Padco Advisors Ii Inc	Institution	1,188	Sold Some	-12	-1.00 %	$6,047	$5,489	$-558	-9.23 %	$6						History of Padco Advisors Ii Inc Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Padco Advisors Inc	Institution	1,624	Added More	100	6.56 %	$8,266	$7,503	$-763	-9.23 %	$-47						History of Padco Advisors Inc Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Rockefeller Financial Services Inc	Institution	1,566	No Change	0	0 %	$7,971	$7,235	$-736	-9.23 %	$0						History of Rockefeller Financial Services Inc Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Russell Frank Co	Institution	25,400	No Change	0	0 %	$129,286	$117,348	$-11,938	-9.23 %	$0						History of Russell Frank Co Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Systematic Financial Management Lp	Institution	6,290	New Holding	6,290	100 %	$32,016	$29,060	$-2,956	-9.23 %	$-2,956						History of Systematic Financial Management Lp Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Teachers Advisors Inc	Institution	29,886	No Change	0	0 %	$152,120	$138,073	$-14,046	-9.23 %	$0						History of Teachers Advisors Inc Ownership Of Symyx Technologies
2010-02-11	2009-12-31	13F-HR	Tiaa Cref Investment Management Llc	Institution	228,227	Added More	24,374	11.95 %	$1,161,675	$1,054,409	$-107,267	-9.23 %	$-11,456						History of Tiaa Cref Investment Management Llc Ownership Of Symyx Technologies
2010-02-10	2009-12-31	13F-HR	Dimensional Fund Advisors Inc	Institution	1,368,346	Added More	628,710	85.00 %	$6,978,565	$6,321,759	$-656,806	-9.41 %	$-301,781						History of Dimensional Fund Advisors Inc Ownership Of Symyx Technologies
2010-02-10	2009-12-31	13F-HR	Globeflex Capital L P	Institution	533,400	Sold Some	-126,635	-19.18 %	$2,720,340	$2,464,308	$-256,032	-9.41 %	$60,785						History of Globeflex Capital L P Ownership Of Symyx Technologies
2010-02-10	2009-12-31	13F-HR	Panagora Asset Management Inc	Institution	500	No Change	0	0 %	$2,550	$2,310	$-240	-9.41 %	$0						History of Panagora Asset Management Inc Ownership Of Symyx Technologies
2010-02-10	2009-12-31	13F-HR	Parametric Portfolio Associates	Institution	23,122	Added More	6,245	37.00 %	$117,922	$106,824	$-11,099	-9.41 %	$-2,998						History of Parametric Portfolio Associates Ownership Of Symyx Technologies
2010-02-09	2009-12-31	13F-HR	Bnp Paribas Arbitrage Sa	Institution		Sold All	-12,017	-100 %				-9.58 %	$5,888						History of Bnp Paribas Arbitrage Sa Ownership Of Symyx Technologies
2010-02-09	2009-12-31	13F-HR	California Public Employees Retirement System	Institution	88,216	New Holding	88,216	100 %	$450,784	$407,558	$-43,226	-9.58 %	$-43,226						History of California Public Employees Retirement System Ownership Of Symyx Technologies
2010-02-09	2009-12-31	13F-HR	New York State Common Retirement Fund	Institution	1,098,536	Added More	568,165	107.12 %	$5,613,519	$5,075,236	$-538,283	-9.58 %	$-278,401						History of New York State Common Retirement Fund Ownership Of Symyx Technologies
2010-02-09	2009-12-31	13F-HR	Oxford Asset Management	Institution	21,606	Sold Some	-3,482	-13.87 %	$110,407	$99,820	$-10,587	-9.58 %	$1,706						History of Oxford Asset Management Ownership Of Symyx Technologies
2010-02-09	2009-12-31	13F-HR	Prescott Group Capital Management Llc	Institution	707,700	No Change	0	0 %	$3,616,347	$3,269,574	$-346,773	-9.58 %	$0						History of Prescott Group Capital Management Llc Ownership Of Symyx Technologies
2010-02-08	2009-12-31	13F-HR	Los Angeles Capital Management And Equity Research Inc	Institution	101,142	Sold Some	-7,000	-6.47 %	$506,721	$467,276	$-39,445	-7.78 %	$2,730						History of Los Angeles Capital Management And Equity Research Inc Ownership Of Symyx Technologies
2010-02-05	2009-12-31	13F-HR	Evercore Wealth Management Llc	No Data	27,300	No Compare			$139,776	$126,126	$-13,650	-9.76 %							History of Evercore Wealth Management Llc Ownership Of Symyx Technologies
2010-02-05	2009-12-31	13F-HR	Gartmore Mutual Fund Capital Trust	Institution	144	Sold Some	-45	-23.80 %	$737	$665	$-72	-9.76 %	$23						History of Gartmore Mutual Fund Capital Trust Ownership Of Symyx Technologies
2010-02-05	2009-12-31	13F-HR	Pnc Financial Services Group Inc	Institution	21,702	Sold Some	-7,223	-24.97 %	$111,114	$100,263	$-10,851	-9.76 %	$3,612						History of Pnc Financial Services Group Inc Ownership Of Symyx Technologies
2010-02-05	2009-12-31	13F-HR	Research Affiliates Llc	Institution		Sold All	-10,027	-100 %				-9.76 %	$5,014						History of Research Affiliates Llc Ownership Of Symyx Technologies
2010-02-05	2009-12-31	13F-HR	Rhumbline Advisers	Institution	53,175	Sold Some	-2,400	-4.31 %	$272,256	$245,669	$-26,588	-9.76 %	$1,200						History of Rhumbline Advisers Ownership Of Symyx Technologies
2010-02-05	2009-11-30	N-CSRS	Sei Institutional Investments Trust - Siit Small Cap Fund	Small-Cap Core		Sold All	-92,475	-100 %				-9.76 %	$46,238						History of Sei Institutional Investments Trust - Siit Small Cap Fund Ownership Of Symyx Technologies
2010-02-05	2009-11-30	N-CSRS	Valic Co I - Health Sciences Fund	Health/Biotech		Sold All	-14,500	-100 %				-9.76 %	$7,250						History of Valic Co I - Health Sciences Fund Ownership Of Symyx Technologies
2010-02-05	2009-11-30	N-CSRS	Valic Co I - Small Cap Index Fund	Small-Cap Core		Sold All	-27,591	-100 %				-9.76 %	$13,796						History of Valic Co I - Small Cap Index Fund Ownership Of Symyx Technologies
2010-02-04	2009-12-31	13F-HR	Clarivest Asset Management Llc	Institution	94,900	Added More	20,800	28.07 %	$475,449	$438,438	$-37,011	-7.78 %	$-8,112						History of Clarivest Asset Management Llc Ownership Of Symyx Technologies
2010-02-04	2009-12-31	13F-HR	Comerica Bank	Institution	12,167	Added More	631	5.46 %	$60,957	$56,212	$-4,745	-7.78 %	$-246						History of Comerica Bank Ownership Of Symyx Technologies
2010-02-04	2009-12-31	13F-HR	Gagnon Securities Llc	Institution	317,798	Sold Some	-53,587	-14.42 %	$1,592,168	$1,468,227	$-123,941	-7.78 %	$20,899						History of Gagnon Securities Llc Ownership Of Symyx Technologies
2010-02-03	2009-12-31	13F-HR	Engemann Asset Management	Institution		Sold All	-96	-100 %				-7.96 %	$38						History of Engemann Asset Management Ownership Of Symyx Technologies
2010-02-02	2009-12-31	13F-HR	Public Employees Retirement Association Of Colorado	Institution	21,500	No Change	0	0 %	$108,575	$99,330	$-9,245	-8.51 %	$0						History of Public Employees Retirement Association Of Colorado Ownership Of Symyx Technologies
2010-02-02	2009-11-30	N-CSRS	Usaa Mutual Funds Trust - Cornerstone Strategy Fund	Specialty & Misc	3,100	No Change	0	0 %	$15,655	$14,322	$-1,333	-8.51 %	$0						History of Usaa Mutual Funds Trust - Cornerstone Strategy Fund Ownership Of Symyx Technologies
2010-01-28	2009-12-31	13F-HR	Regents Of The University Of California	Institution	13,417	No Change	0	0 %	$66,280	$61,987	$-4,293	-6.47 %	$0						History of Regents Of The University Of California Ownership Of Symyx Technologies
2010-01-28	2009-12-31	13F-HR	State Board Of Administration Of Florida Retirement System	Institution	58,760	Added More	1,400	2.44 %	$290,274	$271,471	$-18,803	-6.47 %	$-448						History of State Board Of Administration Of Florida Retirement System Ownership Of Symyx Technologies
2010-01-27	2009-12-31	13F-HR	Brown Capital Management Inc	Institution	5,031,079	Added More	2,464,899	96.05 %	$25,859,746	$23,243,585	$-2,616,161	-10.11 %	$-1,281,747						History of Brown Capital Management Inc Ownership Of Symyx Technologies
2010-01-27	2009-12-31	13F-HR	Tocqueville Asset Management Lp	Institution	306,820	Sold Some	-1,637,610	-84.22 %	$1,577,055	$1,417,508	$-159,546	-10.11 %	$851,557						History of Tocqueville Asset Management Lp Ownership Of Symyx Technologies
2010-01-27	2009-12-31	13F-HR	Tocqueville Asset Management Lp	Institution	306,820	Sold Some	-1,632,234	-84.17 %	$1,577,055	$1,417,508	$-159,546	-10.11 %	$848,762						History of Tocqueville Asset Management Lp Ownership Of Symyx Technologies
2010-01-27	2009-11-30	N-CSR	Fidelity Commonwealth Trust - Fidelity Nasdaq Composite Index Fund	Specialty & Misc	2,794	Sold Some	-231	-7.63 %	$14,361	$12,908	$-1,453	-10.11 %	$120						History of Fidelity Commonwealth Trust - Fidelity Nasdaq Composite Index Fund Ownership Of Symyx Technologies
2010-01-25	2009-12-31	13F-HR	Thomson Horstmann And Bryant Inc	Institution		Sold All	-594,500	-100 %				-5.32 %	$154,570						History of Thomson Horstmann And Bryant Inc Ownership Of Symyx Technologies
2010-01-22	2009-12-31	13F-HR	Strs Ohio	Institution		Sold All	-83,000	-100 %				-7.22 %	$29,880						History of Strs Ohio Ownership Of Symyx Technologies
2010-01-19	2009-12-31	13F-HR	Bank Of New York Mellon Corp	Institution	169,949	Added More	15,565	10.08 %	$931,321	$785,164	$-146,156	-15.69 %	$-13,386						History of Bank Of New York Mellon Corp Ownership Of Symyx Technologies
2010-01-15	2009-12-31	13F-HR	Wagner Investment Management Inc	Institution	100	No Change	0	0 %	$514	$462	$-52	-10.11 %	$0						History of Wagner Investment Management Inc Ownership Of Symyx Technologies
2010-01-14	2009-12-31	13F-HR	Public Employees Retirement System Of Ohio	Institution	41,574	Sold Some	-49,000	-54.09 %	$228,657	$192,072	$-36,585	-16.00 %	$43,120						History of Public Employees Retirement System Of Ohio Ownership Of Symyx Technologies
2010-01-12	2009-09-30	13F-HR/A	Ing Investment Management Co	Institution	14,670	Added More	2,620	21.74 %	$77,018	$67,775	$-9,242	-12.00 %	$-1,651						History of Ing Investment Management Co Ownership Of Symyx Technologies
2010-01-11	2009-10-31	N-CSR	Tocqueville Trust - The Tocqueville Fund	Specialty & Misc		Sold All	-82,800	-100 %				-16.15 %	$73,692						History of Tocqueville Trust - The Tocqueville Fund Ownership Of Symyx Technologies
2010-01-08	2009-10-31	N-CSR	Dfa Investment Dimensions Group Inc - International Core Equity Portfolio	International Small-Mid-Cap Value	155,773	Added More	95,385	157.95 %	$872,329	$719,671	$-152,658	-17.50 %	$-93,477						History of Dfa Investment Dimensions Group Inc - International Core Equity Portfolio Ownership Of Symyx Technologies
2010-01-08	2009-10-31	N-CSR	Dfa Investment Dimensions Group Inc - International Vector Equity Portfolio	No Data	27,296	No Change	0	0 %	$152,858	$126,108	$-26,750	-17.50 %	$0						History of Dfa Investment Dimensions Group Inc - International Vector Equity Portfolio Ownership Of Symyx Technologies
2010-01-08	2009-10-31	N-CSR	Dfa Investment Dimensions Group Inc - Us Sustainability Core 1 Portfolio	No Data	800	No Change	0	0 %	$4,480	$3,696	$-784	-17.50 %	$0						History of Dfa Investment Dimensions Group Inc - Us Sustainability Core 1 Portfolio Ownership Of Symyx Technologies
2010-01-08	2009-10-31	N-CSR	Dfa Investment Dimensions Group Inc - Va Small Value Portfolio	Small-Cap Value		Sold All	-37,339	-100 %				-17.50 %	$36,592						History of Dfa Investment Dimensions Group Inc - Va Small Value Portfolio Ownership Of Symyx Technologies
2010-01-08	2009-10-31	N-CSR	Dfa Investment Trust Co - International Value Series	Multi-Cap Value	40,492	No Change	0	0 %	$226,755	$187,073	$-39,682	-17.50 %	$0						History of Dfa Investment Trust Co - International Value Series Ownership Of Symyx Technologies
2010-01-08	2009-10-31	N-CSRS	Powershares Exchange Traded Fund Trust - Powershares Dividend Achievers Portfolio	Specialty & Misc		Sold All	-2,350,758	-100 %				-17.50 %	$2,303,743						History of Powershares Exchange Traded Fund Trust - Powershares Dividend Achievers Portfolio Ownership Of Symyx Technologies
2010-01-07	2009-10-31	N-CSR	Old Westbury Funds Inc - International Fund	International Multi-Cap Core	8,700	No Change	0	0 %	$47,067	$40,194	$-6,873	-14.60 %	$0						History of Old Westbury Funds Inc - International Fund Ownership Of Symyx Technologies
2010-01-07	2009-10-31	N-CSR	Russell Investment Co - International Fund	International Multi-Cap Core	10,100	No Change	0	0 %	$54,641	$46,662	$-7,979	-14.60 %	$0						History of Russell Investment Co - International Fund Ownership Of Symyx Technologies
2010-01-05	2009-12-31	4	Heritage Trevor	Insider	930	Sold Some	-6,670	-87.76 %	$5,069	$4,297	$-772	-15.22 %	$5,536		X			Pres Symyx Software	History of Heritage Trevor Ownership Of Symyx Technologies
2010-01-05	2009-12-31	4	Heritage Trevor	Insider	7,600	New Holding	7,600	100 %	$41,420	$35,112	$-6,308	-15.22 %	$-6,308		X			Pres Symyx Software	History of Heritage Trevor Ownership Of Symyx Technologies
2010-01-04	2009-09-30	13F-HR/A	California Public Employees Retirement System	Institution		Sold All	-93,716	-100 %				-16.60 %	$86,219						History of California Public Employees Retirement System Ownership Of Symyx Technologies
2009-12-31	2009-09-30	N-Q/A	Rydex Dynamic Funds - Dynamic Russell 2000 Fund	No Data	776	Added More	210	37.10 %	$4,268	$3,585	$-683	-16.00 %	$-185						History of Rydex Dynamic Funds - Dynamic Russell 2000 Fund Ownership Of Symyx Technologies
2009-12-31	2009-09-30	N-Q/A	Rydex Variable Trust - Biotechnology Fund	Health/Biotech	380	Sold Some	-64	-14.41 %	$2,090	$1,756	$-334	-16.00 %	$56						History of Rydex Variable Trust - Biotechnology Fund Ownership Of Symyx Technologies
2009-12-30	2009-10-31	N-Q	Usaa Mutual Funds Trust - Growth Fund	Multi-Cap Growth	700	New Holding	700	100 %	$3,745	$3,234	$-511	-13.64 %	$-511						History of Usaa Mutual Funds Trust - Growth Fund Ownership Of Symyx Technologies
2009-12-29	2009-10-31	N-CSR	Goldman Sachs Trust - Goldman Sachs Structured Small Cap Growth Fund	Gold Oriented	20,871	Sold Some	-2,482	-10.62 %		$96,424		- %							History of Goldman Sachs Trust - Goldman Sachs Structured Small Cap Growth Fund Ownership Of Symyx Technologies
2009-12-29	2009-10-31	N-CSR	Goldman Sachs Trust - Goldman Sachs Structured Small Cap Value Fund	Gold Oriented	78,151	New Holding	78,151	100 %		$361,058		- %							History of Goldman Sachs Trust - Goldman Sachs Structured Small Cap Value Fund Ownership Of Symyx Technologies
2009-12-29	2009-10-31	N-Q	Profunds - Bull Profund	Large-Cap Core	2,560	Added More	1,140	80.28 %		$11,827		- %							History of Profunds - Bull Profund Ownership Of Symyx Technologies
2009-12-15	2009-09-30	13F-HR/A	Forward Management Llc	Institution	38,535	Added More	130	0.33 %	$173,408	$178,032	$4,624	2.66 %	$16						History of Forward Management Llc Ownership Of Symyx Technologies

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